Biomarker responses in fish exposed to polycyclic aromatic hydrocarbons (PAHs): Systematic review and meta-analysis

Santana, Manuela S.; Sandrini-Neto, Leonardo; Neto, Francisco Filipak; Ribeiro, Ciro Alberto de Oliveira; Domênico, Maikon Di; Prodocimo, Maritana Mela

doi:10.1016/j.envpol.2018.07.004

Cited by 127 publications

(31 citation statements)

References 71 publications

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“…GSH binds with ROS to reduce their adverse effects 49 therefore, higher levels of GSH and high GSH/GSSG ratio are mandatory to overcome stress and maintain normal functioning of cells 50,51 . Persistent decline in the ratio of GSH/GSSG in the exposed hatchlings compared to control till end of recovery period hints towards prolonged oxidative stress of the selected sublethal concentrations of TCS in all the species.…”

Section: Discussionmentioning

confidence: 99%

Biomarkers for the toxicity of sublethal concentrations of triclosan to the early life stages of carps

Dar

Sharma

Singh

et al. 2020

Sci Rep

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Accumulation, contents of protein, non-enzymatic antioxidant glutathione (GSH and GSSG), lipid peroxidation product (melondialdehyde-MDA) and organic acids (fumarate, succinate, malate and citrate), and activities of neurological (acetylcholinesterase-AChE), detoxification (glutathione S-transferase-GST) and metabolic (lactate dehydrogenase-LDH, aspartate transaminase-AST and alanine transaminase-ALT) enzymes were recorded in the hatchlings of Cyprinus carpio, Ctenopharyngodon idella, Labeo rohita and Cirrhinus mrigala after 7 and 14 days exposure and 10 days post exposure (recovery period) to sublethal concentrations (0.005, 0.01, 0.02 and 0.05 mg/L) of triclosan, a highly toxic and persistent biocide used in personal care products. Accumulation was maximum between 7–14 days at 0.01 mg/L for C. carpio and L. rohita but at 0.005 mg/L for C. idella and C. mrigala. No triclosan was observed at 0.005 mg/L in C. carpio and C. mrigala after recovery. Significant decline in protein, glutathione and acetylcholinesterase but increase in glutathione S-transferase, lactate dehydrogenase, aspartate transaminase, alanine transaminase, melondialdehyde and organic acids over control during exposure continued till the end of recovery period. Integrated biomarker response (IBR) analysis depicted higher star plot area for glutathione and glutathione S-transferase during initial 7 days of exposure, thereafter, during 7–14 days of exposure and the recovery period, higher star plot area was observed for acetylcholinesterase, aspartate transaminase, alanine transaminase and organic acids. Higher star plot area was observed for protein in all the species throughout the study. The study shows that L. rohita is most sensitive and glutathione, acetylcholinesterase, aspartate transaminase and alanine transaminase are the biomarkers for the toxicity of sublethal concentrations of TCS.

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Section: Discussionmentioning

confidence: 99%

Biomarkers for the toxicity of sublethal concentrations of triclosan to the early life stages of carps

Dar

Sharma

Singh

et al. 2020

Sci Rep

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“…POPs interfere with organisms, compromising multiple physiological processes; they have immunosuppressive properties, are carcinogenic, mutagenic, and teratogenic, and some are known to be endocrine disruptors (Jimenez 1997;Matthiessen 2003;Mikula & Svobodova 2006; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans 2016; Centelleghe et al 2019;Marsili et al 2019). Even naturally occurring contaminants such as PAHs and heavy metals, which have been made more bioavailable by human activities, are known to be important stress factors for marine organisms (Marsili et al 2014(Marsili et al , 2016Scheuhammer et al 2015;Santana et al 2018;Cunningham et al 2019;Lee et al 2019). Furthermore, most studies have demonstrated the existence of pollutants in Chondrichthyans and their environments (Gelsleichter & Walker 2010), but few have examined the impact and effects of chemicals on these organisms (Fuentes-Rios et al 2005;Solé et al 2010aSolé et al , 2010bBarrera-García et al 2012, 2013Vélez-Alavez et al 2013;Alves et al 2016;Marsili et al 2016;Fossi et al 2017;Cullen et al 2019;Lyons & Wynne-Edwards 2019;Ehnert-Russo & Gelsleichter 2020).…”

Section: Introductionmentioning

confidence: 99%

Assessment of the conservation status of Chondrichthyans: underestimation of the pollution threat

Consales

Marsili

2021

The European Zoological Journal

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Cartilaginous fish include sharks, rays, skates, sawfish, and chimaeras. Their habitat ranges from shallow coastal waters to deep ocean floors, estuarine areas as well as rivers and inland waters. Overfishing is considered to be the main threat to their existence, but there are many more stressors that these species face. Pollution is an issue that concerns aquatic organisms at every level, and Chondrichthyans are no exception. Here, we looked at their IUCN Red List assessment, and noticed a lack of information regarding anthropogenic contamination for these species. Out of 1124 cartilaginous fish species assessed, only 17 Selachimorpha and 32 Batoidea species were considered to be facing a "pollution threat"; in most cases, the threat was assigned not from direct ecotoxicological studies of the specimens, but because the species inhabited areas likely to be contaminated. An update on the conservation status of these species is urgently needed. Further, there is a fundamental need to study the effects of contaminants on Chondrichthyans as they play a key role in aquatic ecosystems.

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“…Reactive oxygen species (ROS) are produced when fishes are susceptible to hydrocarbon pollution, and these ROS can lead to cellular damage. Histological indicators can be generated by ROS, and these indicators can be used as biological markers in fishes exposed to toxicants [6]. It is significant to research on effect of ROS on histology of fishes in order to understand if fish species are affected by exposure to contaminants.…”

mentioning

confidence: 99%

Histopathological Biomarkers of Exposure to Monocyclic Aromatic Hydrocarbons in Clarias Ggariepinus (African Catfish)

Doherty

Adeola

Aneyo

et al. 2019

JST

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Biomarker responses in fish exposed to polycyclic aromatic hydrocarbons (PAHs): Systematic review and meta-analysis

Cited by 127 publications

References 71 publications

Biomarkers for the toxicity of sublethal concentrations of triclosan to the early life stages of carps

Biomarkers for the toxicity of sublethal concentrations of triclosan to the early life stages of carps

Assessment of the conservation status of Chondrichthyans: underestimation of the pollution threat

Histopathological Biomarkers of Exposure to Monocyclic Aromatic Hydrocarbons in Clarias Ggariepinus (African Catfish)

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