Biologically active compounds from the rhizomes of iris hungarica

Мykhailenko, Olha; Kovalyov, Volodumyr; Kovalyov, S. V.; Krechun, A. V.

doi:10.24959/ophcj.16.903

Cited by 5 publications

(3 citation statements)

References 4 publications

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“…Similar polyphenolic compounds were detected in the extracts of I. pallida, I. hungarica, I. sibirica , and I. variegata rhizomes as demonstrated by HPLC-DAD and UPLC–MS/MS analyses. Compound identification was based on their co-elution with reference compounds previously isolated from the rhizomes of I. pseudacorus [ 45 ] and I. hungarica [ 13 , 46 , 47 ], as well as based on the UV/MS spectroscopic data. For the qualitative analysis of phenolic compounds, a more selective and sensitive negative ionization mode method was selected for the crude plants [ 48 ].…”

Section: Resultsmentioning

confidence: 99%

“…Previous chemical and pharmacological studies on Iris sp. indicated that the plants contain several classes of secondary metabolites such as flavonoids, isoflavones, and their glycosides, C -glucosylxanthones, quinones, triterpenoids, and stilbene glycosides [ 12 , 13 , 14 ]. These compounds contribute to the observed immunomodulatory [ 15 , 16 ], estrogenic [ 17 , 18 ], antioxidative [ 19 , 20 , 21 ], antibacterial [ 22 , 23 ] and anticholinesterase [ 24 ], cytotoxic [ 11 , 25 ], and anti-osteoporotic activities [ 26 ].…”

Section: Introductionmentioning

confidence: 99%

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Qualitative and Quantitative Analysis of Ukrainian Iris Species: A Fresh Look on Their Antioxidant Content and Biological Activities

et al. 2020

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The major groups of antioxidant compounds (isoflavonoids, xanthones, hydroxycinnamic acids) in the rhizome methanol extracts of four Ukrainian Iris sp. (Iris pallida, Iris hungarica, Iris sibirica, and Iris variegata) were qualitatively and quantitatively analyzed using HPLC-DAD and UPLC-MS/MS. Gallic acid, caffeic acid, mangiferin, tectoridin, irigenin, iristectorigenin B, irisolidone, 5,6-dihydroxy-7,8,3′,5′-tetramethoxyisoflavone, irisolidone-7-O-β-d-glucopyranoside, germanaism B, and nigricin were recognized by comparing their UV/MS spectra, chromatographic retention time (tR) with those of standard reference compounds. I. hungarica and I. variegata showed the highest total amount of phenolic compounds. Germanaism B was the most abundant component in the rhizomes of I. variegata (7.089 ± 0.032 mg/g) and I. hungarica (6.285 ± 0.030 mg/g). The compound analyses showed good calibration curve linearity (r2 > 0.999) and low detection and quantifications limit. These results validated the method for its use in the simultaneous quantitative evaluation of phenolic compounds in the studied Iris sp. I. hungarica and I. variegata rhizomes exhibited antioxidant activity, as demonstrated by the HPLC-ABTS system and NRF2 expression assay and anti-inflammatory activity on respiratory burst in human neutrophils. Moreover, the extracts showed anti-allergic and cytotoxic effects against cancer cells. Anti-coronavirus 229E and lipid formation activities were also evaluated. In summary, potent antioxidant marker compounds were identified in the examined Iris sp.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Qualitative and Quantitative Analysis of Ukrainian Iris Species: A Fresh Look on Their Antioxidant Content and Biological Activities

et al. 2020

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“…According to the results of the previous studies, in the raw material of Iris hungarica the following components were identified: isoflavones (daidzein, formononetin, genistein), flavonols (quercetin), hydroxycinnamic acids (cinnamic, hydroxycinnamic, ferulic, chlorogenic), phenolic acids (galic), xanthones (magniferine, isomangiferine) [14]. The substances of phenolic nature, such as tectorigenin, tectoridin, irigenin, iristectorigenin B, iristectorin B, daidzein, genistein, formononetin, kaempferol, quercetin, mangiferine were also isolated [15,16].…”

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The study of the elemental composition of Iris hungarica and varieties of irises

et al. 2018

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The study of the elemental composition of Iris hungarica and varieties of irises Aim. To determine the elemental composition of leaves and rhizomes of Iris hungarica and dwarf bearded irises. Materials and methods. The objects of the study were leaves and rhizomes of Iris hungarica Waldst et Kit. and 5 varieties of standard dwarf bearded irises (Iridaceae). The content of macro-and microelements in the leaves and rhizomes of irises was determined by atomic emission spectrometry.Results and discussion. For the first time the quantitative content of the mineral complex of Iris hungarica and dwarf bearded irises has been determined by atomic emission spectrometry. In total, 19 elements have been identified; among them there are 5 macroelements (K, Ca, Mg, Na, P), 10 microelements elements (Fe, Si, Al, Mn, Pl, Ni, Mo, Cu, Zn, Sr), 4 ultramicroelements (Co, Cd, As, Hg). The content of heavy, toxic elements are within the permissible limits. The experimental data will be further used to standardize the raw material of irises.Conclusions. The quantitative content of the mineral complex of Iris hungarica and dwarf bearded irises has been identified. According to the research results the raw material of irises can be recommended as an additional source of macro-and microelements. Дослідження елементного складу Iris hungarica та сортів півниківМета. Встановити елементний склад листя та кореневищ півників угорських та карликових бородатих півників. Матеріали та методи. Об'єктами дослідження були листя та кореневища півників угорських (Iris hungarica Waldst et Kit.) та 5 сортів стандартних карликових бородатих півників (Iridaceae). Вміст макро-та мікроелементів у листі та кореневищах півників встановлювали методом атомно-емісійної спектрометрії.Результати та їх обговорення. Вперше кількісний вміст мінерального комплексу півників угорських та карликових півників був встановлений методом атомно-емісійної спектрометрії. Були ідентифіковані 19 елементів, серед яких 5 -макроелементи (K, Ca, Mg, Na, P), 10 -мікроелементи (Fe, Si, Al, Mn, Pb, Ni, Mo, Cu, Zn, Sr), 4 -ультрамікроелементи (Co, Cd, As, Hg). Вміст важких, токсичних елементів знаходиться у допустимих межах. Дані експерименту будуть використані для стандартизації сировини півників.Висновки. Встановлений кількісний вміст мінерального комплексу півників угорських та карликових бородатих півників. Результати досліджень можуть рекомендувати сировину півників як додаткове джерело макрота мікроелементів. Ключові слова: півники; листя; кореневище; елементний склад; атомно-емісійна спектрометрія В. Н. Ковалев, А. В. Кречун, О. А. Михайленко, Е. В. Гришина Исследование элементного состава Iris hungarica и сортов ирисовЦель. Установить элементный состав листьев и корневищ ириса венгерского и карликовых бородатых ирисов методом атомно-эмиссионной спектрометрии с дуговым возбуждением спектра.Материалы и методы. Объектами исследования были листья и корневища ириса венгерского (Iris hungarica Waldst et Kit.) и 5 сортов стандартных карликовых бородатых ирисов (Iridaceae). Содержание мак...

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