Biological Values of Six Partially-Purified Proteins

Protein Requirements of Man: Variations in Obligatory Urinary and Fecal Nitrogen Losses in Young Men

“…Previous studies (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14) have presented data for relatively few individuals, usually under the confining and protective condi tions of the metabolic ward. In the present study the number of individuals is large and the subjects were exposed to the ordinary activities and stresses of everyday living.…”

“…Moreover, the coeffi cient of variation of 10% accepted for BMR (16) was applied to the presumed variation in obligatory urinary N losses. The fact that the data on human subjects (7,9,10) fell below the regression line derived from the other species was merely noted. No quantitative justification was given for further application of the 10% coefficient of variation figure to the sum of the various obligatory N losses.…”

The nutritive value of proteins: general considerations

“…For the rat the biological value of egg proteins is close on IOO (Mitchell & Carman, 1926; Hawley, Murlin, Nasset & Szymanski, 1948;Henry & Kon, 1957) which shows that they are almost completely utilized. Thus the growth rate of rats on a diet containing 9% of egg proteins could not be improved by the addition of any individual amino-acid, save lysine that had a very slight effect, but increase in the proportion of egg proteins in the diet promoted further growth (Mitchell, 1950 Supplementary eflects and the time factor in protein utilization Maximum utilization of proteins can only take place when the energy needs are satisfied by fat and carbohydrate, and all the essential amino-acids are available simultaneously in the correct proportions, together with adequate quantities of nonessential acids, or of non-protein nitrogen.…”

The metabolic roles, pharmacology, and toxicology of lysine.

“…demonstrated both for animal growth [51] and adult human maintenance [52] early in the present century. Based on evaluation of the total knowledge of human protein and IAA requirements accumulated by 1989, the Joint FAOIWHO Expert Consultation on Protein Quality Evaluation [53], concluded that the IAA pattern proposed by the 1985 FAOIWHOI UNU Expert Consultation on Protein and Energy requirements for children of preschool age is currently the most suitable pattern for evaluating protein quality for all age groups above infancy, including adult humans [54].…”