Biological synthesis of titanium dioxide nanoparticles from plants and microorganisms and their potential biomedical applications

Ilyas, Muhammad; Waris, Abdul; Khan, Atta Ullah; Zamel, Doaa; Yar, Lubna; Baset, Abdul; Muhaymin, Abdul; Khan, Sulaiman; Ali, Asmat

doi:10.1016/j.inoche.2021.108968

Cited by 30 publications

(6 citation statements)

References 138 publications

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“…In plant science, gene delivery plays a vital part in the growth of new plant varieties and the development of drought-resistant, pest-resistant, high-yield plants [ 215 ]. The main inherent obstacle to gene delivery in plants is the biomolecule movement within cells through the rigid and multilayered cell wall.…”

Section: Gene Therapymentioning

confidence: 99%

Review on Nanoparticles and Nanostructured Materials: Bioimaging, Biosensing, Drug Delivery, Tissue Engineering, Antimicrobial, and Agro-Food Applications

et al. 2022

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In the last few decades, the vast potential of nanomaterials for biomedical and healthcare applications has been extensively investigated. Several case studies demonstrated that nanomaterials can offer solutions to the current challenges of raw materials in the biomedical and healthcare fields. This review describes the different nanoparticles and nanostructured material synthesis approaches and presents some emerging biomedical, healthcare, and agro-food applications. This review focuses on various nanomaterial types (e.g., spherical, nanorods, nanotubes, nanosheets, nanofibers, core-shell, and mesoporous) that can be synthesized from different raw materials and their emerging applications in bioimaging, biosensing, drug delivery, tissue engineering, antimicrobial, and agro-foods. Depending on their morphology (e.g., size, aspect ratio, geometry, porosity), nanomaterials can be used as formulation modifiers, moisturizers, nanofillers, additives, membranes, and films. As toxicological assessment depends on sizes and morphologies, stringent regulation is needed from the testing of efficient nanomaterials dosages. The challenges and perspectives for an industrial breakthrough of nanomaterials are related to the optimization of production and processing conditions.

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Section: Gene Therapymentioning

confidence: 99%

Review on Nanoparticles and Nanostructured Materials: Bioimaging, Biosensing, Drug Delivery, Tissue Engineering, Antimicrobial, and Agro-Food Applications

et al. 2022

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“…Metallic nanoparticles have shown their outstanding role in biomedical applications [13,[33][34][35]. Currently, these materials can be manufactured and functionalized with groups that facilitate their conjugation with antibodies, drugs, and ligands-these modifications and functionalization open new avenues of potential applications in magnetic separation, biotechnology, and drug delivery.…”

Section: Metallic Nanoparticlesmentioning

confidence: 99%

“…Moreover, metal nanoparticles can be manufactured while modulating their size and morphology as well as functionalization with other ligands, which widen their applications and increase their efficiencies [32,40]. Additionally, biodegradable biomaterials that Metallic nanoparticles have shown their outstanding role in biomedical applications [13,[33][34][35]. Currently, these materials can be manufactured and functionalized with groups that facilitate their conjugation with antibodies, drugs, and ligands-these modifications and functionalization open new avenues of potential applications in magnetic separation, biotechnology, and drug delivery.…”

Section: Metallic Nanoparticlesmentioning

confidence: 99%

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Applications of Various Types of Nanomaterials for the Treatment of Neurological Disorders

et al. 2022

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Neurological disorders (NDs) are recognized as one of the major health concerns globally. According to the World Health Organization (WHO), neurological disorders are one of the main causes of mortality worldwide. Neurological disorders include Alzheimer’s disease, Parkinson′s disease, Huntington′s disease, Amyotrophic lateral sclerosis, Frontotemporal dementia, Prion disease, Brain tumor, Spinal cord injury, and Stroke. These diseases are considered incurable diseases because no specific therapies are available to cross the blood-brain barrier (BBB) and reach the brain in a significant amount for the pharmacological effect in the brain. There is a need for the development of strategies that can improve the efficacy of drugs and circumvent BBB. One of the promising approaches is the use of different types of nano-scale materials. These nano-based drugs have the ability to increase the therapeutic effect, reduce toxicity, exhibit good stability, targeted delivery, and drug loading capacity. Different types and shapes of nanomaterials have been widely used for the treatment of neurological disorders, including quantum dots, dendrimers, metallic nanoparticles, polymeric nanoparticles, carbon nanotubes, liposomes, and micelles. These nanoparticles have unique characteristics, including sensitivity, selectivity, and the ability to cross the BBB when used in nano-sized particles, and are widely used for imaging studies and treatment of NDs. In this review, we briefly summarized the recent literature on the use of various nanomaterials and their mechanism of action for the treatment of various types of neurological disorders.

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“…These approaches are divided into three categories: physical, biological, and chemical processes [57]. However, among the three procedures, biological procedures offer many advantages because the processes are not complicated, harmless, and cost-effective [58]. Reducing and capping agents play an important role in AgNPs synthesis.…”

Section: Fig 2 Variations Of Nanoparticles Shape ■ Green Synthesis (B...mentioning

confidence: 99%

A Review on Green Synthesis, Antimicrobial Applications and Toxicity of Silver Nanoparticles Mediated by Plant Extract

Salnus¹,

Wahab

Arfah

et al. 2022

Indones. J. Chem.

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Nanotechnology explores nanoscale materials that can be used in a wide range of industries such as biotechnology, cosmetics, drug delivery, nanomedicine, and biosensors. Nanoparticles in diverse shapes and sizes can be prepared through physical, chemical, and biological methods. The employment of reducing agents, which will change their form, size range, level of stability, and interaction, is a crucial part thus employing a biological approach is necessary. Chemically generated metal oxide nanoparticles raise considerable issues owing to the usage of hazardous and poisonous chemicals, as well as the potential for conservational impairment. In contrast, the production of silver nanoparticles using the principal method of green synthesis has found a special place in research that is considered more environmentally approachable requiring the use to produce non-toxic nanomaterials. Plants and polymer materials have received a lot of interest in the preparation of nanoparticles since they are renewable and affordable. In this review, we present a comprehensive overview of more ecologically friendly synthesis techniques that use plant extracts to make silver nanoparticles and their application as antibacterial agents, as well as toxicity features based on the shape, size range, and phytochemical mechanism of plants.

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Biological synthesis of titanium dioxide nanoparticles from plants and microorganisms and their potential biomedical applications

Cited by 30 publications

References 138 publications

Review on Nanoparticles and Nanostructured Materials: Bioimaging, Biosensing, Drug Delivery, Tissue Engineering, Antimicrobial, and Agro-Food Applications

Review on Nanoparticles and Nanostructured Materials: Bioimaging, Biosensing, Drug Delivery, Tissue Engineering, Antimicrobial, and Agro-Food Applications

Applications of Various Types of Nanomaterials for the Treatment of Neurological Disorders

A Review on Green Synthesis, Antimicrobial Applications and Toxicity of Silver Nanoparticles Mediated by Plant Extract

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