Biological synthesis of 2,5-bis(hydroxymethyl)furan from biomass-derived 5-hydroxymethylfurfural by E. coli CCZU-K14 whole cells

Biotransformation of 5-hydroxymethylfurfural into 2,5-dihydroxymethylfuran by Ganoderma sessile and toxicological assessment of both compounds

“…S1 represented ectoenzyme and S2 represented endoenzyme to DHMF using whole resting cells through a new highly tolerant yeast strain-Meyerozyma guilliermondii SC1103 with a yield of 86% (Li et al 2017). Moreover, DHMF was biologically synthesized from 5-HMF with E. coli CCZU-K14 cells (He et al 2018). Given that the biocatalysis might come from relevant enzyme of G. sessile, the crude enzymes were extracted from fermented G. sessile and applied to biotransform 5-HMF.…”

“…In fact, selective hydrogenation of 5-HMF and selective of catalysts are the key on the chemical synthesis of DHMF (Fulignati et al 2019). Meanwhile, there are also studies showing that this transformation can be accomplished through biotransformation (He et al 2018;Li et al 2017).…”

Biocatalytic Transformation of 5-Hydroxymethylfurfural into 2,5-di(hydroxymethyl)furan by a Newly Isolated Fusarium striatum Strain

“…The biocatalytic preparation of DHMF remains an attractive alternative to the current chemical pathways due to its higher selectivity, mild conditions and environmental friendliness [14]. However, the toxicity of HMF towards microorganisms poses a hard challenge for its biotransformation into DHMF with whole cells, and literature is still limited in spite of all the significant advances performed in the last years using yeast and bacteria as biocatalysts [15][16][17][18][19][20]. This becomes apparent in literature regarding this biotransformation when performed with filamentous fungi, as it is scarce and focused on the biodetoxification of lignocellulosic material in the bioethanol production process.…”

Highly efficient production of 2,5-dihydroxymethylfuran from biomass-derived 5-hydroxymethylfurfural over an amorphous and mesoporous zirconium phosphonate catalyst

“…To achieve this goal, designing and developing an appropriate catalytic hydrogenation system is particularly significant. Gratifyingly, many biocatalytic hydrogenation systems [15][16][17] and chemocatalytic hydrogenation systems (such as traditional hydrogenation system [18] , transfer hydrogenation system [19] , photocatalytic hydrogenation system [20] , electrocatalytic hydrogenation system [21] , photoelectrocatalytic hydrogenation system [22] and disproportionation reaction system [23] ) have been gradually explored and employed in recent years. Among these catalytic hydrogenation systems, the catalytic transfer hydrogenation system via Meerwein-Ponndorf-Verley (MPV) reduction reaction, which is highly selective for the hydrogenation of C = O in carbonyl compounds by using alcohols as the insitu hydrogen donors and reaction solvents [24] , has currently received increasing concerns.…”