Biological responses to hydroxyapatite surfaces deposited via a co-incident microblasting technique

O’Hare, Peter; Meenan, Brian J.; Burke, George; Byrne, G.; Dowling, Denis P.; Hunt, John A.

doi:10.1016/j.biomaterials.2009.09.067

Cited by 125 publications

(110 citation statements)

References 27 publications

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“…While the CoBlast process has been reported to operate at gauge pressures of 90 psig (0.62 MPa) and at a jet height of 20 mm from the surface [11,13,14]. The corresponding shot preening process typically runs at lower gauge pressures of 40 -60 psig (0.28-0.41 MPa) and at nozzle orifice to substrate heights of up to 200 mm [15,16].…”

Section: Resultsmentioning

confidence: 99%

“…All surface blasting was carried out using a Comco Standard Lathe as described previously [11,13,14]. The processing utilised twin nozzles, one for the HA stream and a separate nozzle for the abrasive/shot peen flow ( Figure 2).…”

Section: Sample Preparationmentioning

confidence: 99%

“…As shown in Figure 8, the Shot Peen treated alloy surface appears to be relatively homogeneous and smooth, while the CoBlast surface reveals a series of deep gouges, cracks and other features derived from the impact of the abrasive particles on the surface. This abrasion is associated with the removal of the outer titanium oxide layer and its replacement with a HA mechano-chemically bonded coating [11].…”

Section: Coating Chemistry and Topographymentioning

confidence: 99%

“…Ishikawa et al produced a coating by simply blasting HA at a metal implant, but this did not gain market favour, possibly due to low adhesion [10,11].…”

Section: Introductionmentioning

confidence: 99%

“…This technique which is called CoBlast TM has been shown to successfully deposit coatings which offer promising biological responses both in-vitro and in-vivo [11,13,14].…”

mentioning

confidence: 99%

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Comparison between shot peening and abrasive blasting processes as deposition methods for hydroxyapatite coatings onto a titanium alloy

Byrne

O’Neill

Twomey

et al. 2013

Surface and Coatings Technology

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HighlightsComparison of two low temperature deposition methods for HA Combining silica shot with a flow of HA powder worked effectively Replacing the silica with alumina abrasive produced a more adherent coating AbstractRecent studies have shown that combining a compressed air jet with entrained hydroxyapatite (HA) particles with a jet of abrasive particles can be used to deposit a well adhered crystalline HA coatings onto titanium substrates. A similar particle bombardment process utilising a flow of shot peen particles and a flow of suitable powder particles has been used to deposit a range of coatings, though the deposition of bioceramic powders have not yet been reported by this method. In this study a direct comparison between the shot peen and abrasive bombardment processes has been undertaken to determine which technique yields coatings exhibiting higher levels of adhesion on titanium alloy substrates. Both processes were shown to effectively deposit a layer of crystalline apatite onto the titanium substrates over a range of pressures and jet to substrate heights. It was observed that for both processes that an increase in particle kinetic energy producing corresponding enhancements in both deposition rate and surface roughness. The shot peen process however produced a smooth layer of laminar apatite, which was readily removed from the surface using a scratch adhesion test technique.In contrast the combination of a jet of HA and abrasive powders resulted in an increase in surface abrasion and increased mechanical interlocking of the HA into the metal surface was observed. The mechano-chemical affect achieved resulted in a better adhered HA layer. The surface morphology obtained using the two treatments was significantly different with an increase in the average roughness (R a ) of ≈ 70 and 80 % for samples treated with abrasive particles over shot peen. This difference in surface treatment is further highlighted by the removal of the HA using an acid etch. The roughness (R a ) of the underlying titanium layer after this removal is, on average, >175 % higher for the surface treated with the abrasive particles during HA deposition.

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Section: Resultsmentioning

confidence: 99%

Section: Sample Preparationmentioning

confidence: 99%

Section: Coating Chemistry and Topographymentioning

confidence: 99%

“…Ishikawa et al produced a coating by simply blasting HA at a metal implant, but this did not gain market favour, possibly due to low adhesion [10,11].…”

Section: Introductionmentioning

confidence: 99%

“…This technique which is called CoBlast TM has been shown to successfully deposit coatings which offer promising biological responses both in-vitro and in-vivo [11,13,14].…”

mentioning

confidence: 99%

See 3 more Smart Citations

Comparison between shot peening and abrasive blasting processes as deposition methods for hydroxyapatite coatings onto a titanium alloy

Byrne

O’Neill

Twomey

et al. 2013

Surface and Coatings Technology

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Osteoconductivity and growth factor production by MG63 osteoblastic cells on bioglass‐coated orthopedic implants

Tan

Naciri

Al‐Rubeai

2010

Biotech & Bioengineering

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We have produced Bioglass coatings for Orthopedic implants by using a novel coating technique, CoBlast. The two resultant surfaces, designated BG and hydroxyapatite (HA)/BG, were compared with their HA counterpart, OsteoZip in terms of osteoblastic cell attachment, adhesion, proliferation, differentiation, and growth factor production. BG and HA/BG were demonstrated by goniometry to be more hydrophilic than OsteoZip. This corresponded to enhanced protein adsorption, cell attachment, and cell adhesion documented by both quantitative and qualitative assessments. BG and HA/BG surfaces had a significant initial release of Si and Ca ions, and this was consistent with elevated cell proliferation and basic fibroblast growth factor levels. However, OsteoZip, being similar to HA/BG, exhibited better osteogenic differentiation than BG did, shown by augmented differentiation marker activity at both protein and mRNA levels. Sandwich ELISA was used to quantify angiopoietin and inducible nitric oxide synthase which are involved in peri-prosthetic angiogenesis and aseptic loosening of total hip replacement, respectively. Both Bioglass-derived coatings provide superior initial osteoconductivity to OsteoZip, and HA/Bioglass composite coating outruns in long-term osteogenic differentiation and prognostic bioprocesses. The novel coatings discovered in this study have significant potential in providing both orthopedic and therapeutic functions.

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Synthesis and Characterization of Hydroxyapatite Using Ammonium Hydroxide and Ethylenediaminetetraacetic Acid

Park

Kim

Choi³

et al. 2015

Bulletin Korean Chem Soc

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Biological responses to hydroxyapatite surfaces deposited via a co-incident microblasting technique

Cited by 125 publications

References 27 publications

Comparison between shot peening and abrasive blasting processes as deposition methods for hydroxyapatite coatings onto a titanium alloy

Comparison between shot peening and abrasive blasting processes as deposition methods for hydroxyapatite coatings onto a titanium alloy

Osteoconductivity and growth factor production by MG63 osteoblastic cells on bioglass‐coated orthopedic implants

Synthesis and Characterization of Hydroxyapatite Using Ammonium Hydroxide and Ethylenediaminetetraacetic Acid

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