2018
DOI: 10.23736/s1121-421x.18.02479-0
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Biological properties and pathogenicity factors of Helicobacter pylori

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Cited by 12 publications
(3 citation statements)
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“…Numerous studies have shown that H. pylori infection is the leading bacterial cause of both malignant and non-malignant gastroduodenal diseases and is also involved in extra-gastroduodenal disorders. Among these, the most common disorders are peptic and duodenal ulceration, acute and chronic gastritis (which may lead to atrophic gastritis), and gastric adenocarcinoma (B-cell gastric lymphoma and mucosa-associated lymphoid tissue (MALT) lymphoma) [10,11]. However, most of the risk reduction due to improved socio-economic status (even in the absence of specific preventive strategies) is thought to stem from reduced H. pylori infection rates [12].…”
Section: Introductionmentioning
confidence: 99%
“…Numerous studies have shown that H. pylori infection is the leading bacterial cause of both malignant and non-malignant gastroduodenal diseases and is also involved in extra-gastroduodenal disorders. Among these, the most common disorders are peptic and duodenal ulceration, acute and chronic gastritis (which may lead to atrophic gastritis), and gastric adenocarcinoma (B-cell gastric lymphoma and mucosa-associated lymphoid tissue (MALT) lymphoma) [10,11]. However, most of the risk reduction due to improved socio-economic status (even in the absence of specific preventive strategies) is thought to stem from reduced H. pylori infection rates [12].…”
Section: Introductionmentioning
confidence: 99%
“…Type 2 diabetes is high blood sugar levels caused by a lack of a hormone called insulin either the broken beta cells aren't making enough insulin or the insulin it makes doesn't work properly called insulin resistance, living with obesity or overweight, other factors include high blood pressure, age, lifestyle, family history, genetics and which is chronically observed in the patients with diabetes [9]. Diabetes may cause long-term damage to different organs, especially eyes, kidneys, nervous system, heart, and blood vessels [10]. At least 80% of the patients with diabetes will die due to the consequences of cardiac complications [11].…”
Section: Introductionmentioning
confidence: 99%
“…H. pylori genome has more than 30 genes which encode for OMPs, that can be divided into Helicobacter outer membrane proteins (Hop) subgroups. [26][27][28][29] Some of these proteins have been identified. Blood group antigen binding adhesin (BabA), the first discovered, is involved in binding with ABO group (Lewis antigen, expressed in stomach) and leads to the synthesis of proinflammatory cytokines.…”
mentioning
confidence: 99%