2019
DOI: 10.23736/s1120-4826.19.02555-2
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Diagnosis of Helicobacter pylori infection: a look into molecular aspects of urea breath test

Abstract: Helicobacter pylori (H. pylori) is a bacterium that selectively colonizes gastric epithelium in more than 50% people over the world. The infection is usually acquired in early childhood and rarely resolved spontaneously; transmission is mostly person to person, and occurs by fecal-oral or oraloral modality. Diagnosis and antibiotic treatment may lead to eradication of H. pylori, improving the prevention and the outcome of gastric and extragastric diseases. Many tests are currently available for the diagnosis o… Show more

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Cited by 12 publications
(1 citation statement)
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“…Since the human stomach is an unfriendly place for microbial survival, H. pylori has developed a repertoire of acid resistance mechanisms which allow the microorganism to overcome the mucous layer. In particular, via the enzyme urease, the bacterium creates a cloud of acid neutralizing chemicals around it, offering protection from the acid [ 14 ]. H. pylori infection is accepted as the most important cause of gastritis and PUD in humans.…”
Section: Dyspepsia: Definition and Clinical Classificationmentioning
confidence: 99%
“…Since the human stomach is an unfriendly place for microbial survival, H. pylori has developed a repertoire of acid resistance mechanisms which allow the microorganism to overcome the mucous layer. In particular, via the enzyme urease, the bacterium creates a cloud of acid neutralizing chemicals around it, offering protection from the acid [ 14 ]. H. pylori infection is accepted as the most important cause of gastritis and PUD in humans.…”
Section: Dyspepsia: Definition and Clinical Classificationmentioning
confidence: 99%