Biological Monitoring of Fuel Stations Workers Occupationally Exposed to Petroleum Products

El-Said, Khaled; El-Noueam, Amr

doi:10.21608/jhiph.2010.20622

Cited by 4 publications

(3 citation statements)

References 4 publications

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“…The findings of the present research show that exposure to crude oil can cause notable changes in the renal and hepatic functions of study participants, especially when compared to study participants in the control group, Alahdab field workers had significantly higher levels of ALT, AST, urea, creatinine, and bilirubin. The significant rise in ALT and AST coincides with findings from studies carried out in Brazil, Egypt, Nigeria, India, and other countries [36][37][38].…”

Section: Discussionsupporting

confidence: 86%

Early Kidney and liver Dysfunction Associated with Exposure to Crude Oil in Al-Ahdab field

Alqurashy

2023

wjps

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Although the detrimental effects of crude oil on many types of plants and animals have been broadly studied, not enough research has been done on how exposure to oil affects human health. In the present work, we tried to inspect their effect on the liver and kidney functions of the Al-Ahdab field workers as well as the local population living close to the oil drilling sites (Fadak city). A randomly selected 150 subjects they don’t suffer from chronic diseases (50 subjects from workeres of Al-Ahdab field They have been working in the field for more than ten years and 50 subjects from Fadak city they don’t work in the Al-Ahdab field and 50 subjects from Al- kut city far from the Al-Ahdab field also they don’t work in the Al-Ahdab field as control) aged higher than 40 years were taken under consideration. The level of urea, creatinine, bilirubin, aspartate transaminase and alanine transaminase enzymes in serum were evaluated by spectrophotometer. Where it was found that the levels of urea, creatinine, liver enzymes, and bilirubin were higher among the Al-Ahdab field workers than the control. We also found that the residents of Fadak City, which is very close to the Al-Ahdab field oil extraction, were also high compared to the control but less than the Al-Ahdab field workers. The study reveals that long-term exposure to the pollutants produce from oil extraction may lead to harm effect to liver and kidney functions of workers in oil extraction field and populations living in polluted sites.

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Section: Discussionsupporting

confidence: 86%

Early Kidney and liver Dysfunction Associated with Exposure to Crude Oil in Al-Ahdab field

Alqurashy

2023

wjps

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“…Whereas, Total bilirubin had no significantly different between exposed and controls. The significantly increase in ALT and AST is in line with other studies conducted in Egypt, Nigeria, Turkey, Palestine, India, and Brazil [13,[30][31][32][33][34]. This observation may be due to the fact that hydrocarbons which are a major component of petroleum products that are metabolized in the liver by CYP450 2E1 oxidative pathways which contribute to the production of free radicals and quinine metabolites such as phenol, hydroquinone, benzoquinone;1,2,4 benzenetriol [17].…”

Section: Plos Onesupporting

confidence: 91%

“…Exposure to benzene, toluene, and xylenes are considered to be the most hazardous, predominantly benzene because of its carcinogenic potency [12,13]. The health impact of the exposed subjects are due to free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) [14].…”

Section: Introductionmentioning

confidence: 99%

Assessment of liver and renal function tests among gasoline exposed gas station workers in Mekelle city, Tigray region, Northern Ethiopia

et al. 2020

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Background Volatile organic compounds such as gasoline and other fuels are associated with a wide variety of deleterious health effects including liver and kidney diseases. Gasoline station workers are exposed to a mixture of hydrocarbons during dispensing. However, no published studies investigated the liver and renal function tests of gasoline station workers in Ethiopia. Therefore the aim of this study was to assess liver and renal function tests among gasoline station workers. Method A comparative cross sectional study was conduct from January 2018 to April 2018 at Mekelle city, Tigray region, Northern Ethiopia. Liver and renal function tests were analyzed on gasoline exposed (n = 43) and controls (n = 47) by Pentra C400 automated clinical chemistry analyzer. Student independent t-test and one way-ANOVA statistical methods were employed using SPSS Ver23. P-value < 0.05 was regarded as statistically significant. Result The mean level of ALT, AST, Urea, creatinine, and uric acid was significantly higher among gasoline stations workers when compared to control study participants. There was also a significant increase in ALT, AST, Urea, creatinine and uric acid among gasoline stations with above 6 years exposure when compared with those exposed for �2 and3-6years. Conclusion These findings suggest that increasing liver and renal parameters may be associated with exposure to gasoline and it is dependent on time of exposure to gasoline.

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The effect of occupational exposure to petrol on pulmonary function parameters: a review and meta-analysis

Moghadam

Afshari

Moosazadeh

et al. 2019

Reviews on Environmental Health

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Abstract Introduction Exposure to petrol and gasoline can have harmful effects on the lungs. This review aimed to summarize the reported effects of this exposure on pulmonary function parameters. Methods Relevant studies were identified by a comprehensive search in PubMed, Scopus, Science Direct and Google Scholar databases. Irrelevant studies were excluded. Quality assessment was performed using the Newcastle-Ottawa score (NOS). The standard mean difference of pulmonary parameters between exposed and unexposed petrol station attendants was pooled using random effects. Meta-regression was used to investigate factors probably related to heterogeneity. Studies affecting the total estimates were assessed during sensitivity analysis. The Egger test was performed to investigate any evidence of publication bias. Results Eventually, 26 studies entered the meta-analysis, and the pooled standard difference [95% confidence interval (CI)] of forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC, vital capacity (VC), peak expiratory flow (PEF), forced expiratory flow (FEF25-75) and maximum voluntary ventilation (MVV) in the exposed minus unexposed groups was −1.08 L (95% CI: −1.38, −0.78), −0.92 L (−1.15, −0.69), −0.65 (−1.01, −0.30), −0.51 L (−0.96, −0.06), −0.96 L/s (−1.21, −0.69), −0.78 L/s (1.14, −0.42) and −0.58 L/min (−0.90, −0.27), respectively, and showed a decrease in all pulmonary parameters in the exposed group. Conclusion Occupational exposure to petrol fumes is a risk factor for lung function and there is a reverse relation between lung function and the duration of exposure.

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Biological Monitoring of Fuel Stations Workers Occupationally Exposed to Petroleum Products

Cited by 4 publications

References 4 publications

Early Kidney and liver Dysfunction Associated with Exposure to Crude Oil in Al-Ahdab field

Early Kidney and liver Dysfunction Associated with Exposure to Crude Oil in Al-Ahdab field

Assessment of liver and renal function tests among gasoline exposed gas station workers in Mekelle city, Tigray region, Northern Ethiopia

The effect of occupational exposure to petrol on pulmonary function parameters: a review and meta-analysis

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