Biological Effects Of Nuclear Radiation On The Monkey (Macaca Mulatta)

Dose- and ApoE Isoform-Dependent Cognitive Injury after Cranial56Fe Irradiation in Female Mice

“…Animals were subdivided into three dose groups, and the findings suggested that as doses increased, responses to a variety of tasks were degraded, with females generally showing better performance than males. Other examples of weapons test investigations, such as those by Pickering et al (1958) with estimated doses from 2.2 to 11.8 Gy, also measured acute radiation sickness and LD 50 but revealed the prompt onset of and sustained increase in nondirected visual activity (predominance of visual activity without apparent fixation), nondirected locomotor activity (e.g., bouncing, pacing, or swinging), object-directed activity (to cage parts or experimenter), and self-directed activity (responses to the subject's own bodies). These higher dose observations are less useful due to the associated severe morbidity.…”

Biological Effects of Nuclear Explosions (BENE) Domain Guide

“…from Hiroshima and Nagasaki survivors Pickering et al, 1958b Project 39.6, Biological Effects of Nuclear Radiation on the Monkey (Macaca Mulatta)…”