Biological effects of long‐term exposure of rats to 970‐MHz radiofrequency radiation

Smialowicz, Ralph J.; Weil, Claude; Marsh, Philip; Riddle, Marie M.; Rogers, Ronald R.; Rehnberg, Blair F.

doi:10.1002/bem.2250020309

Cited by 16 publications

(8 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Beischer et al [1973] reported that serum triglycerides of blood samples decreased 14 h after supper when human subjects were exposed to a low-intensity magnetic field. However, higher serum levels of triglycerides were observed [Smialowicz et al, 1981] after rats were exposed to 970-MHz electromagnetic radiation.…”

Section: Discussionmentioning

confidence: 94%

Alimentary hyperlipemia of rabbits is affected by exposure to low‐intensity pulsed magnetic fields

Luo

Shen

Xie

et al. 2007

Bioelectromagnetics

View full text Add to dashboard Cite

An experimental study was carried out in rabbits to investigate the effects of exposing rabbits to low-intensity pulsed magnetic fields (PMFs) on alimentary hyperlipemia. Thirty female white big ear rabbits were randomly divided into three groups. The normal group was fed with a standard chow diet and the other two groups (hyperlipid and magnetic) were fed with the chow diet supplemented with cholesterol, yolk powder and lard. The magnetic group was exposed to 15 Hz pulsed magnetic fields. After 8 weeks, levels of blood lipid and indices of hemorheology were examined. In addition, histomorphologic changes of hepatic and myocardial tissues were compared across the groups respectively. Compared with the hyperlipid group, hemorheology indices of the magnetic group reduced significantly from 12.80% to 38.05% (P < 0.01) indicating lower blood viscosity. Similarly, compared with the hyperlipid group, the levels of total cholesterol and triglycerides in the magnetic group decreased 40.52% and 52.42% (P < 0.01). On the contrary, high density lipoprotein (HDL) value obviously increased 66.67% (P < 0.01). Furthermore, compared with the control group, the values of triglycerides and HDL of the magnetic group did not show statistical differences (P > 0.05). The deposit of fatty material on the inner lining of thoracic aorta wall of the magnetic group was significantly lighter than that of the hyperlipid group. Numerous aggregation of lipoids emerged among myocardial myofibrils in the hyperlipid group, while no notable change was found in both the magnetic and control group. The results indicate that low-intensity PMFs could be helpful for the treatment of alimentary hyperlipemia.

show abstract

Section: Discussionmentioning

confidence: 94%

Alimentary hyperlipemia of rabbits is affected by exposure to low‐intensity pulsed magnetic fields

Luo

Shen

Xie

et al. 2007

Bioelectromagnetics

View full text Add to dashboard Cite

show abstract

“…Nevertheless, the two studies also did not find statistically significant change for HDL-c level, which is inconsistent with our results. In addition, many animal studies also reported that exposure to EMF did not change the blood levels of TC (Celikozlu et al 2012;Kim et al 2006;Portet and Cabanes 1988;Smialowicz et al 1981;Torres-Duran et al 2007) or TG (Bahaoddini et al 2008;Elferchichi et al 2010;Hori et al 2012;Portet and Cabanes 1988;Torres-Duran et al 2007), while other studies found an increase in blood TC or TG (Smialowicz et al 1981), even a decrease in TC (Bahaoddini et al 2008;Bellossi et al 1998;Coskun and Comlekci 2010;Hori et al 2012;Luo et al 2007), TG (Bellossi et al 1998;Coskun and Comlekci 2010;Luo et al 2007) and HDL-c (Luo et al 2007). Methodological variations such as the difference of exposure conditions (e.g., resource type, frequency, intensity, duration, and continuity of EMF exposure), subjects' susceptibility, or detection methods may have given rise to such inconsistent findings across studies.…”

Section: Discussionmentioning

confidence: 99%

Effects of electromagnetic fields on serum lipids in workers of a power plant

Wang

Zheng

et al. 2015

Environ Sci Pollut Res

View full text Add to dashboard Cite

This study aimed to evaluate the effects of electromagnetic fields (EMF) exposure on levels of serum lipids in workers of an electric power plant. A cross-sectional study was carried out in an electric power plant in Zhejiang province, China, from August to September 2011. All participants were divided into two groups with high occupational EMF exposure and low occupational EMF exposure. The occupational EMF exposure included radiofrequency EMF and extremely low-frequency EMF. Occupational EMF exposure was associated with an increased level of low-density lipoprotein cholesterol (LDL-c; β = 0.17 mmol/L, P = 0.022). High EMF exposure group with longer employment duration, longer daily EMF exposure duration, and more mobile phone or electric fee per month had significantly higher levels of total cholesterol, LDL-c, or triglyceride than the corresponding reference group. However, significantly decreased level of high-density lipoprotein cholesterol was only observed in high EMF exposure group with more mobile phone fee per month. Similar results were also found in 544 participants with available data of serum lipids in 2010. The findings showed that chronic EMF exposure was associated with the change of serum lipid levels. EMF exposure might modulate the process of lipid metabolism.

show abstract

“…They also found that multiple exposures at levels below the threshold were cumulative if done within 1 h of one another, but not if spaced 24 h apart, even if the sum of the energy absorption values exceeded the threshold. Smialowicz et al [1981] exposed 16 rats almost continuously for 69-70 consecutive days to 970 MHz RFEMF at 2.5 W/kg. There were no significant differences between RFEMF exposed and sham exposed rats in erythrocyte count, total or differential leukocyte counts, mean cell volume of erythrocytes, hemoglobin concentration, or hematocrit.…”

Section: Effects On Immunological Functionmentioning

confidence: 99%

Radiofrequency (RF) effects on blood cells, cardiac, endocrine, and immunological functions

Black

Heynick

2003

Bioelectromagnetics

View full text Add to dashboard Cite

Effects of radiofrequency electromagnetic fields (RFEMF) on the pituitary adrenocortical (ACTH), growth (GH), and thyroid (TSH) hormones have been extensively studied, and there is coherent research on reproductive hormones (FSH and LH). Those effects which have been identified are clearly caused by heating. The exposure thresholds for these effects in living mammals, including primates, have been established. There is limited evidence that indicates no interaction between RFEMF and the pineal gland or an effect on prolactin from the pituitary gland. Studies of RFEMF exposed blood cells have shown that changes or damage do not occur unless the cells are heated. White cells (leukocytes) are much more sensitive than red cells (erythrocytes) but white cell effects remain consistent with normal physiological responses to systemic temperature fluctuation. Lifetime studies of RFEMF exposed animals show no cumulative adverse effects in their endocrine, hematological, or immune systems. Cardiovascular tissue is not directly affected adversely in the absence of significant RFEMF heating or electric currents. The regulation of blood pressure is not influenced by ultra high frequency (UHF) RFEMF at levels commonly encountered in the use of mobile communication devices. Bioelectromagnetics Supplement 6:S187-S195,

show abstract

Biological effects of long‐term exposure of rats to 970‐MHz radiofrequency radiation

Cited by 16 publications

References 6 publications

Alimentary hyperlipemia of rabbits is affected by exposure to low‐intensity pulsed magnetic fields

Alimentary hyperlipemia of rabbits is affected by exposure to low‐intensity pulsed magnetic fields

Effects of electromagnetic fields on serum lipids in workers of a power plant

Radiofrequency (RF) effects on blood cells, cardiac, endocrine, and immunological functions

Contact Info

Product

Resources

About