Biological activity of mannosylerythritol lipids on the mammalian cells

Coelho, Ana Letícia Silva; Feuser, Paulo Emílio; Carciofi, Bruno Augusto Mattar; Oliveira, Débora de

doi:10.1007/s00253-020-10857-9

Cited by 7 publications

(3 citation statements)

References 57 publications

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“…Lipids were an important constitution in food science, which plays multiple functions on food, nutrient, and human being health (Brahe et al, 2013). Lipid molecules imply massive biological matrices, lipids are an essential nutrient and flavour substances in icewine (Coelho et al, 2020). No qualitative and quantitative studies on lipids in icewine are available.…”

Section: Discussionmentioning

confidence: 99%

Determination of icewine lipids by Ultra High Performance Liquid Tandem Chromatography Quadrupole Time-of-Flight Mass Spectrometry

Yang¹,

Qu²,

Wan³

et al. 2023

Food Sci. Technol (Campinas)

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Backgroud: Icewine is a unique food in the world. Lipids in icewine are nutritious and healthy for humans. However, limited studies are available on the qualitative and quantitative analysis of icewine. Method: UPLC-QTOF-MS approach to study lipids in icewine. Bioinformatics strategies will expand the applications of lipidomics in food science,OPLS-DA) was performed to visualise group separation and recognized significantly transform metabolites. Results: In the present study, lipid molecules belonging to 5 classes were qualitatively and quantitatively analysed. The lipids studied were as track: 102 triacylglycerols (TAG), 18 free fatty acids (FFA), 5 diacylglycerols (DAG), 6 ceramides and sphingosine-1-phosphate (Cer), and 1 N-palmitoyl-D-erythro-sphingosylphosphorylcholine (SM). The Shangri-La icewine has higher TAG and FFA content than the Canadian icewine. However, in Canadian icewine samples, the DAG (16:0/16:1) content (398.26 μg/mL) was higher than that of Shangri-La icewine specimens (522.43 μg/mL). The SM (14:0) content in Canadian icewine was higher than that of Shangri-La icewine. Conclusion:UPLC-QTOF-MS is an effective method for detecting lipids in icewine samples. The primary fundamental lipids in icewine samples were TAG, FFA, DAG, Cer, and SM. Therefore, Shangri-La icewine is more nutritious for human health than Canadian icewine.

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Section: Discussionmentioning

confidence: 99%

Determination of icewine lipids by Ultra High Performance Liquid Tandem Chromatography Quadrupole Time-of-Flight Mass Spectrometry

Yang¹,

Qu²,

Wan³

et al. 2023

Food Sci. Technol (Campinas)

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“…MELs are chemically composed of mannose, erythritol residue, and two fatty acids chains. Their chemical structures vary based on the number and position of the acetyl group on mannose and erythritol, as well as the length and saturation degree of fatty acid chains [10,15,16]. According to the degree of acetylation at C 4 and C 6 positions on mannose, MELs are classified into four typical homologues including MEL-A (diacetylated at mannosyl C-4 ′ and C-6 ′ ), MEL-B (monoacetylated at mannosyl C-6 ′ ), MEL-C (monoacetylated at mannosyl C-4 ′ ), and MEL-D (deacetylated) (Figure 1) [10,12,[15][16][17].…”

Section: Introductionmentioning

confidence: 99%

“…Their chemical structures vary based on the number and position of the acetyl group on mannose and erythritol, as well as the length and saturation degree of fatty acid chains [10,15,16]. According to the degree of acetylation at C 4 and C 6 positions on mannose, MELs are classified into four typical homologues including MEL-A (diacetylated at mannosyl C-4 ′ and C-6 ′ ), MEL-B (monoacetylated at mannosyl C-6 ′ ), MEL-C (monoacetylated at mannosyl C-4 ′ ), and MEL-D (deacetylated) (Figure 1) [10,12,[15][16][17]. The unique structures and features of different MELs expand their applications in various industries such as nanomaterials, bioscience, macromolecular chemistry, cosmetics, and medicines.…”

Section: Introductionmentioning

confidence: 99%

Promising Application, Efficient Production, and Genetic Basis of Mannosylerythritol Lipids

Liu,

Liu

2024

Biomolecules

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Mannosylerythritol lipids (MELs) are a class of glycolipids that have been receiving increasing attention in recent years due to their diverse biological activities. MELs are produced by certain fungi and display a range of bioactivities, making them attractive candidates for various applications in medicine, agriculture, and biotechnology. Despite their remarkable qualities, industrial-scale production of MELs remains a challenge for fungal strains. Excellent fungal strains and fermentation processes are essential for the efficient production of MELs, so efforts have been made to improve the fermentation yield by screening high-yielding strains, optimizing fermentation conditions, and improving product purification processes. The availability of the genome sequence is pivotal for elucidating the genetic basis of fungal MEL biosynthesis. This review aims to shed light on the applications of MELs and provide insights into the genetic basis for efficient MEL production. Additionally, this review offers new perspectives on optimizing MEL production, contributing to the advancement of sustainable biosurfactant technologies.

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