Biological activity exerted by omega-3 fatty acids on body mass index, glucose, total cholesterol and blood pressure in obese children

Abstract

Background: Obesity is risk factor to development cardiovascular diseases. There are several studies which indicate that fatty acids can exert changes in body fat in children. However, the results found relatively are few and have generally been conducted over short time periods with small sample sizes, making it difficult to draw definitive conclusions.Objective: In this study the effect induced by omega-3 fatty acids on some biological parameters such as glucose, total cholesterol and body mass index levels in obese children were evaluated.Methods: A dietary intake of gummies with omega-3 fatty acids at dose (100-350 mg) was administered to obese children. Then, glucose, total cholesterol and body mass index levels were determinate using an apparatus (accutrend pluss) and enzyme-immunoassay techniques. Results:The results showed that dietary intake of gummies with omega-3 fatty acids induces significantly changes on total cholesterol and body mass index levels in obese girls compared with obese boys. Conclusions:All these data suggest that dietary intakes of omega-3 fatty acids could be used for the treatment of degree of obesity in obese girls. However, it is important to mention that it is also necessary to evaluate the beneficial effect of omega-3 fatty acids on other biological parameters involved in the degree of obesity as well as the possible toxicity involved in its administration.great controversy about the effect exerted by intake dietary of omega-3 fatty acids against obesity. Therefore, in this study the effect produced by omega-3 fatty acids on some factors associated with obesity such as glucose, body mass index, total cholesterol, and blood pressure levels was evaluated on obese children. Material and MethodsFifth and sixth graders (n=300) in two San Francisco de Campeche Mexico schools were invited to participate in a dietary intake gummy with omega-3 fatty acids at dose of 100 to 350 mg. The parents were informed about the nature and the purpose of this study, and a consent form was signed by parents. In addition, the protocol of this research was previously approved by the ethical committee at the University Autonomous of Campeche.

Expanding the Role of Sub-Exploited DOE-High Energy Extraction and Metabolomic Profiling towards Agro-Byproduct Valorization: The Case of Carotenoid-Rich Apricot Pulp

“…Furthermore, extracts of Group 2 (Table S5), mostly obtained by UAE at a high US power and solvent/material ratio, can result in an extract with combined biological activities due to their significant content of carotenoids (improving eye health, immune-modulating properties, anti-allergic, anti-aging, and sun-protective activity) [13,54], choline (enhancing brain health and cognitive function, affecting detoxification pathways and organs, such as the liver and kidneys) [55][56][57], myo-inositol (promoting female fertility, treating polycystic ovary syndrome, reducing anxiety, and restoring insulin resistance) [58][59][60], and unsaturated fatty acids (health-promoting agents against fat burning, affecting inflammation, steroid signaling, and membrane-bound protein functions, participating in glucose/lipid metabolism) [61][62][63].…”

Omega-3 gantz-azidoen propietate onuragarriak zenbait egoera klinikotan

“…Obesitatea eta intsulinarekiko erresistentzia zeuzkaten umeekin egindako entseguetan adiponektinaren maila igotzea eta inflamazio egoera nahiz intsulinarekiko erresistentzia jaistea lortu zen omega-3 gantz gehigarrien bidez [82]. Omega-3-en bidez gorputz-masa, tentsio arteriala eta kolesterol maila jaisten dira [83]. Gainera, omega-3 GAk aktibitate fisikoarekin konbinatzen zituzten umeek triglizerido eta intsulinarekiko erresistentzia ebaluatzeko probaren (HOMA) mailak aktibitate fisikoa egiten zutenek baino gehiago jaistea lortu zuten [84].…”

Dyslipidemia in Childhood Obesity: A Review

“…Garcia-Cervera et al in their study showed that intake diet of omega-3 polyunsaturated fatty acids decreased body mass index and cholesterol in a dose-dependent approach. 50 Preliminary data suggests that Fibrates may also be potentially useful to decrease dyslipidemia. 51 Niacin is the most effective HDL enhancer and is suggested only as adjunctive therapy in children under supervision of a lipid specialist.…”