Biological Activities of three Nigerian Spices - <i>Laurus nobilis</i> Linn, <i>Murraya koenigii</i> (L) Spreng and <i>Thymus vulgaris</i> Linn

Abstract

Purpose: To evaluate the biological properties of polyphenol extracts of three spices -Laurus nobilis (bay), Murayya koenigii (curry) and Thymus vulgaris (thyme) from

New Tricks for Old Guys: Recent Developments in the Chemistry, Biochemistry, Applications and Exploitation of Selected Species from the Lamiaceae Family

“…The antibacterial potential of thyme is well recognized and documented; recently, Cheurfa and Allem [433] tested [434] obtaining excellent results as the extract of this herb had a high antiglycation effect with 50 % inhibitory concentration (IC 50 ) of 0.02 mg/mL. As already stated for essential oils (see previous paragraphs), the use of nanoconstructs can modulate and even ameliorate the bioactivities of vegetable matrices; Proks et al [435] conducted an experiment on four different cancer cell lines: (12), quercetin (30) and phloridzin (54).…”

“…The antibacterial potential of thyme is well recognized and documented; recently, Cheurfa and Allem tested the aqueous and hydro‐alcoholic extracts prepared from Thymus vulgaris and other vegetable matrices ( Aloysia triphylla , Pistacia lentiscus , Olea europaea leaves and Trigonella foenum‐graecum seeds) on a collection of pathogenic bacteria responsible for gastroenteritis, where some of them isolated from clinical samples ( Escherichia coli, Staphylococcus aureus, Citrobacter freundii, Pseudomonas aeruginosa, Proteus mirabilis, Proteus vulgaris and Salmonella typhimurium ), thus obtaining encouraging results against all the strains. The antidiabetic effect measured as in vitro antiglycation activity (ability of the extracts to inhibit the methyl glyoxal mediated development of fluorescence of bovine serum albumin BSA) of a 80 % acetone extract from Thymus vulgaris (thyme) was studied by Kazeem and others obtaining excellent results as the extract of this herb had a high antiglycation effect with 50 % inhibitory concentration (IC 50 ) of 0.02 mg/mL. As already stated for essential oils (see previous paragraphs), the use of nano‐constructs can modulate and even ameliorate the bioactivities of vegetable matrices; Proks et al .…”

In vitro evaluation of antioxidant, antineurodegenerative and antidiabetic activities of Ocimum basilicum L., Laurus nobilis L. leaves and Citrus reticulata Blanco peel extracts

“…The majority of data on the α-glucosidase inhibitory activity of L. nobilis is regarding to the essential oil, while the information on extracts is scarce. However, Kazeem et al (2016) tested acetone extracts of bay leaves which displayed high antiglycation and antioxidant potential. Indrianingsih et al (2015) have found that L. nobilis methanolic extract at the concentration of 0.2 mg/mL inhibited 47.26% α-glucosidase, which is in agreement with the results obtained in this study for the cultivated L. nobilis.…”

Phytochemicals and Biological Activities of Laurel Tree (Laurus nobilis)

“…However, the analysis of characteristic mass fragmentation pathways of proanthocyanidins has allowed a better accurate identification of them in laurel wood [88]. In this way, it was possible to achieve the tentative identification of four dimeric (170,174,175,177), five trimeric (168,169,171,172,176) and one tetrameric (173) proantho-cyanidins, establishing the kind of monomer that conform them, its relative position in the structure and the kind of bond established among monomers [88]. Moreover, four dimeric (178,179,181,182) and two trimeric proanthocyanidins (180,183) have also been isolated from laurel wood [88].…”

“…Other solvents have also been used for the extraction of antioxidants from laurel leaves: acetone [171,184,187], diethyl ether [177]; chloroform [86,177] and ethyl acetate [177]. Among all these solvents, acetone and ethyl acetate get the most active extracts [171,177].…”