Biokompatibilität

Wintermantel, E.; Shah-Derler, Brigitte; Bruinink, A.; Petitmermet, M.; Blum, J.; Ha, Suk-Woo

doi:10.1007/978-3-540-74925-7_3

Cited by 3 publications

(1 citation statement)

References 32 publications

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“…With respect to the mechanical properties, the material should present a high resistance to external forces like bending, compression, and traction, while simultaneously having Young's modulus similar to the surrounding bone tissue (cortical bone: 13.8 GPa, spongy bone: 1.38 GPa [ 5 ] ). [ 3,6 ] Nowadays, titanium is one of the most implanted materials because of its bioinertness, high fatigue strength, nontoxicity, [ 7 ] and osseointegration ability. [ 8 ] However, the high Young's modulus of titanium (110 GPa) leads to “stress shielding,” [ 9 ] an inhomogeneous stress transfer between the implant and the surrounding bone, which can lead to implant loosening.…”

Section: Introductionmentioning

confidence: 99%

Plasma surface modification and three‐dimensional structuring of additively manufactured polyetheretherketone implants for improvement of osseointegration

Strauss,

Bruyas,

Gonzalez

et al. 2023

Plasma Processes & Polymers

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Osseointegration is highly desirable for implants used for bone replacement. Polyetheretherketone (PEEK) is an attractive material due to its characteristics such as high biocompatibility and Young's modulus similar to human bones. However, PEEK is bioinert, meaning cells do not adhere and proliferate on its surface. This problem is addressed in this study, with the goal of enhancing osseointegration of additively manufactured PEEK. The influences of surface modifications and porous structures on cellular behavior were assessed by wettability and in vitro tests with subclone of the human osteosarcoma cell line‐2 osteoblasts. Overall, the combination of surface modification, type of plasma process used, atmospheric pressure versus vacuum‐based, and surface structuring, especially gyroid structures, improve the cellular proliferation on PEEK. Therefore, its ability to enhance osseointegration is highly promising.

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