Bioinspired Zinc Oxide Nanoparticles Using Lycopersicon esculentum for Antimicrobial and Anticancer Applications

Vijayakumar, Sekar; Vaseeharan, Baskaralingam; Sudhakaran, R.; Jeyakandan, Jeyaraman; Ramasamy, Palaniappan; Sonawane, Avinash; Padhi, Avinash; Velusamy, Palaniyandi; Anbu, Periasamy; Faggio, Caterina

doi:10.1007/s10876-019-01590-z

Cited by 54 publications

(15 citation statements)

References 52 publications

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“…2 . The same diffraction value was noticed in ZnO-NPs using Lycopersicon esculentum and Cynara scolymus leaf extract [ 8 , 32 ]. In this study, the lattice planes clearly indicate that ZnO-NPs formation and its hexagonal phase and wurtzite structure of ZnO-NPs.…”

Section: Resultssupporting

confidence: 66%

“…The method was followed by Vijayakumar et al [ 8 ]. The solution was centrifuged at 10,000 rpm (10,956 g ) for 12 min.…”

Section: Methodsmentioning

confidence: 99%

“…The green synthesis method are more advantageous when compare to physical and chemical methods because of their eco-friendly, low cost, increase economic and large-scale synthesis. ZnO nanoparticles have been effectively orchestrated utilizing plants such as, Musa ornate and Zea mays [ 6 ], Drosophila melanogaster [ 7 ], Lycopersicon esculentum [ 8 ] and Murraya koenigii [ 9 ]. Medicinal plants have a rich source of secondary metabolites and also folkloric sacred texts reports a large number of medicinal plants for different therapeutic applications.…”

Section: Introductionmentioning

confidence: 99%

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Metal oxide nanoparticle synthesis (ZnO-NPs) of Knoxia sumatrensis (Retz.) DC. Aqueous leaf extract and It’s evaluation of their antioxidant, anti-proliferative and larvicidal activities

et al. 2021

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In around the world, mosquito control is considered a most important because of the incapable of synthetic insecticides and the ecological pollution about by them. In this manner, need the eco-friendly insecticides to efficient control the mosquito disease is the need of the hour. We synthesized the eco-friendly of zinc oxide nanoparticles (ZnO-NPs) using the Knoxia sumatrensis aqueous leaf extract ( Ks- ALE) as a reducing and stabilizing agent. The synthesis of ZnO-NPs was confirmed by UV with an absorption peak at 354 nm. ZnO-NPs crystal structure was analyzed by X-ray diffraction (XRD). Fourier transform infrared spectroscopy (FT-IR) spectra revealed the chloride, cyclic alcohols, sulfonamies, carboxylic acids, oximes, phosphines, alkenes and alcohol & phenol. Field emission-scanning electron microscopy (FE-SEM) showed that the NP’s are rod shaped with 50–80 nm size and also energy dispersive spectra (EDaX) spectra showed presence of zinc. Antioxidant assay showed superior activity and evidenced by DPPH, ABTS and H 2 O 2 radical assays. Furthermore, the ZnO-NPs exhibited strong activity in MCF-7 cell line with IC 50 value is 58.87 μg/mL. Mosquito larvicidal activity of ZnO-NPs produced significant activity and excellent larvicidal activity was noticed in Cx. quinquefasciatus with LC 50 0.08, mg/mL and LC 90 19.46 mg/mL. This study suggests that synthesized ZnO-NPs using Knoxia sumatrensis leaf extract have good biological activities and it makes them an ideal candidate for pharmacological studies.

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Section: Resultssupporting

confidence: 66%

“…The method was followed by Vijayakumar et al [ 8 ]. The solution was centrifuged at 10,000 rpm (10,956 g ) for 12 min.…”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Metal oxide nanoparticle synthesis (ZnO-NPs) of Knoxia sumatrensis (Retz.) DC. Aqueous leaf extract and It’s evaluation of their antioxidant, anti-proliferative and larvicidal activities

et al. 2021

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“…ZnO nanoparticles have enhanced antibacterial properties and efficiency, and effectively inhibit human pathogenic bacteria [ 12 ]. ZnONPs have great antibacterial effects against both Gram-positive (+ve) and Gram-negative (−ve) bacteria [ 13 ]. The antibacterial activity of ZnONPs increases concomitant to a decrease in particle size [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

Interactive Effects of Biosynthesized Nanocomposites and Their Antimicrobial and Cytotoxic Potentials

et al. 2021

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The present study investigated the biosynthesis of silver (AgNPs), zinc oxide (ZnONPs) and titanium dioxide (TiO2NPs) nanoparticles using Aspergillusoryzae, Aspergillusterreus and Fusariumoxysporum. Nanocomposites (NCs) were successfully synthesized by mixing nanoparticles using a Sonic Vibra-Cell VC/VCX processor. A number of analytical techniques were used to characterize the synthesized biological metal nanoparticles. Several experiments tested biologically synthesized metal nanoparticles and nanocomposites against two types of human pathogenic bacteria, including Gram-positive Staphylococcus aureusand methicillin-resistant Staphylococcus aureus (MRSA), and Gram-negative Escherichia coli and Pseudomonasaeruginosa. Additionally, the antitumor activity in HCT-116 cells (colonic carcinoma) was also evaluated. Significant antimicrobial effects of various synthesized forms of nanoparticles and nanocomposites against E. coli and P. aeruginosa bacteria were detected. Various synthesized biogenic forms of nanoparticles and nanocomposite (9.0 to 29 mm in diameter) had high antibacterial activity and high antitumor activity against HCT-116 cells (colonic carcinoma) with IC50 values of 0.7–100 µg/mL. Biosynthesized NPs are considered an alternative to large-scale biosynthesized metallic nanoparticles and nanocomposites, are simple and cost effective, and provide stable nanomaterials.

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“…Nanotechnology is one of the most advanced technologies that has emerged from the convergence of physics, chemistry, and biology sciences producing various types of materials including nanoparticles (NPs) with at least one dimension below 100 nm [ 1 , 2 , 3 , 4 , 5 , 6 ]. Metal oxide nanoparticles, as a very important class of NPs, are highly persistent in the environment and food chain [ 7 ] making them very dangerous for the environment and aquatic organisms.…”

Section: Introductionmentioning

confidence: 99%

Chemically and Green Synthesized ZnO Nanoparticles Alter Key Immunological Molecules in Common Carp (Cyprinus carpio) Skin Mucus

Rashidian

Lazado

Mahboub

et al. 2021

IJMS

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This study was conducted to compare the effects of commercially available (C) and green synthesized (GS) Zinc oxide nanoparticles (ZnO-NPs) on immunological responses of common carp (Cyprinus carpio) skin mucus. GS ZnO-NPs were generated using Thymus pubescent and characterized by UV–vis diffuse reflectance spectroscopy (DRS), Fourier-transform infrared spectroscopy (FTIR), X-ray powder diffraction (XRD), scanning electron microscope (SEM), and energy-dispersive X-ray spectroscopy (EDX). Fish (n = 150) were randomly allocated into five groups in triplicate and received a waterborne concentration of 0% (control), 25%, and 50% of LC50 96 h of commercially available (C1 and C2) and green synthesized ZnO-NPs (GS1 and GS2) for 21 days. Results from XRD displayed ZnO-NPs with 58 nm in size and UV-vis DRS, EDX, and FT-IR analysis showed that some functional groups from plant extract bonded to the surface of NPs. The SEM images showed that ZnO-NPs have conical morphology. Acute toxicity study showed a higher dose of LC5096h for green synthesized ZnO-NPs (78.9 mg.L−1) compared to the commercial source (59.95 mg.L−1). The highest activity of lysozyme and alternative complement activity (ACH50) were found in control and GS1 groups. A significant decrease in alkaline phosphatase activity (ALP) was found in C1 and C2 groups compared to other treatments. Protease activity (P) was significantly decreased in the C2 group compared to the control and GS groups. Total immunoglobulin (total Ig) content was the highest in the control. In addition, total Ig in the GS1 group was higher than GS2. The exposure to ZnO-NPs lowered total protein content in all experimental groups when compared to control. Present findings revealed lower induced immunosuppressive effects by green synthesized ZnO-NPs on key parameters of fish skin mucus.

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Bioinspired Zinc Oxide Nanoparticles Using Lycopersicon esculentum for Antimicrobial and Anticancer Applications

Cited by 54 publications

References 52 publications

Metal oxide nanoparticle synthesis (ZnO-NPs) of Knoxia sumatrensis (Retz.) DC. Aqueous leaf extract and It’s evaluation of their antioxidant, anti-proliferative and larvicidal activities

Metal oxide nanoparticle synthesis (ZnO-NPs) of Knoxia sumatrensis (Retz.) DC. Aqueous leaf extract and It’s evaluation of their antioxidant, anti-proliferative and larvicidal activities

Interactive Effects of Biosynthesized Nanocomposites and Their Antimicrobial and Cytotoxic Potentials

Chemically and Green Synthesized ZnO Nanoparticles Alter Key Immunological Molecules in Common Carp (Cyprinus carpio) Skin Mucus

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