Bioinert ceramic biomaterials: advanced applications

Ivanova, Elena P.; Bazaka, Kateryna; Crawford, Russell J.

doi:10.1533/9781782422662.173

Cited by 6 publications

(7 citation statements)

References 37 publications

(27 reference statements)

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“…Compared to polymers and ceramic biomaterials, metals are characterized by higher electrical conductivity. As such, they have been used to deposit electrodes in artificial electronic organs [12].…”

Section: Methodsmentioning

confidence: 99%

“…• Ceramic materials, e.g., aluminum oxide, zirconium oxide, calcium phosphate, etc., are used as bone tissue substitutes. Ceramic biomaterials are non-metallic inorganic substances produced from powdered raw materials by a firing process, which gives them strength [1,12]. They are generally hard, have low electrical and thermal conductivity, low tensile strength, but high compressive strength.…”

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confidence: 99%

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Analysis of Biocompatible Metallic Materials used in Medicine

Gerhátová,

Paták,

Babincová

et al. 2024

J. Phys.: Conf. Ser.

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The paper presents the results of the analysis of two biocompatible materials, Kirschner wires of different thicknesses. Kirschner wires (K-wires) are stainless steel pins used in surgery to fix bone fragments and to provide an anchor for skeletal traction. The K-wires are produced in different diameters. In the present work, a scanning electron microscopy and light microscopy were employed to document the microstructure of two K-wires with different thicknesses. Before observation, the wires were prepared by a standard metallographic procedure (grinding and polishing) followed by electrolytic etching. The chemical composition was determined by studying the wires using quantitative energy-dispersive X-ray spectrometry. It has been found that the chemical composition of the materials corresponds to Cr-Ni stainless steel. In the thick Kirschner wire (sample no. 1) a deformed microstructure after drawing was observed. Sample no. 2 (thin Kirschner wire), on the other hand, consisted of polyhedral austenitic grains, which were formed after recrystallization annealing. Furthermore, isolated microparticles were observed and assigned to titanium nitride. A Vickers hardness test was also performed on the samples. It has been found that the hardness of sample no. 1 was 428.8 HV 0.5. The average hardness of sample no. 2 was 213.4 HV 0.5. It can be concluded that recrystallization annealing decreases the hardness of the material. The K-wires with smaller diameter are thus easier to bend which facilitates their fixation in human body.

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Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

Analysis of Biocompatible Metallic Materials used in Medicine

Gerhátová,

Paták,

Babincová

et al. 2024

J. Phys.: Conf. Ser.

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“…65,66 The bending and compressive strengths of dense HA ceramics are 20–80 MPa and 100–900 MPa, respectively, with Young’s modulus of 70–120 MPa and hardness of 500–800 HV. 67 Therefore, the deposition of calcium ions and the formation of a phosphate layer when exposed to simulated body fluids (SBF) are hypothesised to be crucial steps for the initiation of the growth of bone-like apatite on biocompatible implants. 68 Zhang et al.…”

Section: Surface Treatments Of Ti Alloysmentioning

confidence: 99%

Additively manufactured titanium alloys and effect of hydroxyapatite coating for biomedical applications: A review

Jaafar

Zainol

et al. 2020

Proceedings of the Institution of Mechanical Engineers, Part L:

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Metallic implants are extensively used to treat a spectrum of orthopaedic related disorders. Among the metals, titanium and its alloys are considered most excellent and indispensable material for the production of orthopaedic implants regarding their sterling mechanical properties and exceptional biocompatibility. Recently, rapid progress in developing non-toxic titanium-based alloys with modulus similar to that of human bone has inspired researchers globally. Thus, many studies have focused on titanium alloys, their heat treatment processes and several processing technologies. Additive manufacturing has been designed to enhance their mechanical properties tailored towards biomedical applications. Inarguably, the need to further improve on the implant’s biocompatibility with bodily environment for optimum service life is of great importance. Hence, hydroxyapatite coating provides an improvement as demonstrated by in vitro as well as in vivo studies. The present article critically reviews, based on recent scientific literatures, the progress made thus far in the development of titanium-based alloys, additive manufacturing processes and their heat and surface treatments tailored towards biomedical applications.

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“…Bioinert ceramics are copiously used in applications that require mechanically strong and resilient wear-and corrosion-resistant materials with excellent tribological properties, for example as femur heads and acetabular cups of hip endoprostheses but also as intervertebral parts, in knee arthroplasty, and as dental root implants. These properties have made aluminum oxide, zirconium oxide, titanium dioxide, silicon nitride, pyrolytic graphite and diamondlike carbon important contenders for parts of load-carrying implants [3]. However, the inherent brittleness of ceramics and their finite capability to integrate with tissues restrict their clinical application at present.…”

Section: Introductionmentioning

confidence: 99%

Silicon Nitride, a Close to Ideal Ceramic Material for Medical Application

Heimann¹

2021

Preprint

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This topical review describes the results of recent research into and development of silicon nitride, a ceramic material with unique properties. The outcome of this ongoing research strongly encourages the use of monolithic silicon nitride and coatings as contemporary and future biomaterial for a variety of medical applications. Crystallographic structure, synthesis and processing of monolithic structures and coatings, and examples of their medical applications are covered that relate to spinal, orthopedic and dental implants, bone grafts and scaffolds, platforms for intelligent synthetic neural circuits, antibacterial and antiviral particles and coatings, optical biosensors, and nano-photonic waveguides for sophisticated medical diagnostic devices. The examples provided show convincingly that silicon nitride is destined to become a leader to replace titanium and other entrenched biomaterials in many fields of medicine.

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Bioinert ceramic biomaterials: advanced applications

Cited by 6 publications

References 37 publications

Analysis of Biocompatible Metallic Materials used in Medicine

Analysis of Biocompatible Metallic Materials used in Medicine

Additively manufactured titanium alloys and effect of hydroxyapatite coating for biomedical applications: A review

Silicon Nitride, a Close to Ideal Ceramic Material for Medical Application

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