Biofilms of pathogenic bacteria in pig industry

Abstract

In the industrial pig farm for 26 thousand heads, the analysis of the influence of a forage factor on bacteria carriers of a uterine pig population in connection with mass morbidity of dairy piglets on anaerobic enterotoxemia is carried out. Actinobacillus pleuropneumonia, Pasteurella multocida, Clostridium perfringens, Neisseria spp., Candida albicans, Aspergillus niger which are able to form biofilms, were isolated from five samples of “SK-1” compound feed for pregnant sows and from the blood of animals (n=20) fed with this compound feed. The structural basis of the most stable biofilms in vitro were the aerobic fungi Aspergillus niger and Candida albicans. Biofilm-forming variants of these bacteria showed multidrug resistance to 30 antimicrobial drugs (synthetic penicillins, cephalosporins, fluoroquinolones, aminoglycosides, tetracyclines, combination drugs). Isolates of associative microflora isolated from the blood of sows were pathogenic for 30% of laboratory mice. It was found that probiotic agent No1 (composition based on Bischofite with probiotics) showed the universal bactericidal activity against the bacteria Actinobacillus pleuropneumonia, Pasteurella multocida, Clostridium perfringens, Neisseria spp.

Study of the toxicity and effectiveness of an antiparasitic agent based on tinidazole and fenbendazole

“…Only a scientifically grounded complex of veterinary, sanitary and technological measures ensures the conduct of animal husbandry at a high level (Tomley & Shirley, 2009;Shkromada et al, 2019a;Palii et al, 2020a). In turn, infectious (Stegniy et al, 2019;Kolchyk et al, 2020;Palii et al, 2020b) and parasitic (Majeed et al, 2015;Paliy et al, 2018b;Liu et al, 2020) animal diseases are a significant limiting factor in the development of many livestock industries. Invasive diseases cause tremendous harm to the animal's organism because parasites destroy organs and tissues, poison the whole body with their metabolic products, which cause hypovitaminosis, and weaken immunity, creating conditions for the occurrence of other diseases (Britton et al, 2011).…”

Conception of the 'feed’s chain' for porcine circovirus-bacterial infections in piggery

“…Паралельно, у тих же господарствах, упродовж 4 років також дослідили 637 проб зерна кормового ячменю (по 70-120 г зерна кожна проба) у 37 партіях зразків, відібраних з бурту/годівниці методом «конверту». Через можливу присутність у пробах зерна мікробних біоплівок, їхні екстракти досліджували у розведенні 1:30-1:50 [11].…”