Bioethical issues and legal frameworks of surrogacy: A global perspective about the right to health and dignity

Frati, Paola; Russa, Raffaele La; Santurro, Alessandro; Fineschi, Benedetta; Paolo, Marco Di; Scopetti, Matteo; Turillazzi, Emanuela; Fineschi, Vittorio

doi:10.1016/j.ejogrb.2020.12.020

Cited by 20 publications

(14 citation statements)

References 89 publications

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“…For patients presenting absolute uterine-factor infertility who have functional ovaries, such as is the case for MRKH patients, and for patients having undergone a partial or total hysterectomy, the only assisted fertility treatment option available is in vitro fertilisation followed by surrogacy to carry the foetus to term. This treatment comes with a plethora of ethical and legal barriers, where availability depends on the surrogacy laws and socioeconomic barriers of each country [ 71 ]. Surrogacy can be quite costly to individuals and carries cultural and religious barriers.…”

Section: Tissue Engineering In Gynecologymentioning

confidence: 99%

Tissue Engineering in Gynecology

Brownell

Chabaud

Bolduc

2022

IJMS

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Female gynecological organ dysfunction can cause infertility and psychological distress, decreasing the quality of life of affected women. Incidence is constantly increasing due to growing rates of cancer and increase of childbearing age in the developed world. Current treatments are often unable to restore organ function, and occasionally are the cause of female infertility. Alternative treatment options are currently being developed in order to face the inadequacy of current practices. In this review, pathologies and current treatments of gynecological organs (ovaries, uterus, and vagina) are described. State-of-the-art of tissue engineering alternatives to common practices are evaluated with a focus on in vivo models. Tissue engineering is an ever-expanding field, integrating various domains of modern science to create sophisticated tissue substitutes in the hope of repairing or replacing dysfunctional organs using autologous cells. Its application to gynecology has the potential of restoring female fertility and sexual wellbeing.

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Section: Tissue Engineering In Gynecologymentioning

confidence: 99%

Tissue Engineering in Gynecology

Brownell

Chabaud

Bolduc

2022

IJMS

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“…The gratuity is not resolved in the pure and simple lack or renunciation of a pecuniary compensation, but it is characterized by the intent of solidarity and the achievement of a predetermined result not left to the free determination of the donor. Moreover, gratuitousness constitutes a guarantee of the freedom of consent, removed from the constraints of economic necessity[ 71 ].…”

Section: Ethical Issuesmentioning

confidence: 99%

Pancreatic transplant surgery and stem cell therapy: Finding the balance between therapeutic advances and ethical principles

Padovano¹,

Scopetti²,

Manetti³

et al. 2022

WJSC

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The latest achievements in the field of pancreas transplantation and stem cell therapy require an effort by the scientific community to clarify the ethical implications of pioneering treatments, often characterized by high complexity from a surgical point of view, due to transplantation of multiple organs at the same time or at different times, and from an immunological point of view for stem cell therapy. The fundamental value in the field of organ transplants is, of course, a solidarity principle, namely that of protecting the health and life of people for whom transplantation is a condition of functional recovery, or even of survival. The nature of this value is that of a concept to which the legal discipline of transplants entrusts its own ethical dignity and for which it has ensured a constitutional recognition in different systems. The general principle of respect for human life, both of the donor and of the recipient, evokes the need not to put oneself and one’s neighbor in dangerous conditions. The present ethical reflection aims to find a balance between the latest therapeutic advances and several concepts including the idea of the person, the respect due to the dead, the voluntary nature of the donation and the consent to the same, the gratuitousness of the donation, the scientific progress and the development of surgical techniques, and the policies of health promotion.

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“…the only assisted fertility treatment option available is in vitro fertilisation followed by surrogacy to carry the foetus to term. This treatment comes with a plethora of ethical and legal barriers, where availability depends on a surrogacy laws and socioeconomic barriers in each country [66]. Surrogacy can be quite costly to individuals and carry cultural and religious barriers.…”

Section: Current Treatmentmentioning

confidence: 99%

Tissue Engineering in Gynecology

Brownell¹,

Chabaud²,

Bolduc³

2022

Preprint

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Female gynecological organ dysfunction can cause infertility and psychological distress, decreasing quality of life of affected women. Incidence is constantly increasing due to growing rates of cancer and delaying of childbearing age in the developed world. Current treatments are often unable to restore organ function, and occasionally are the cause for female infertility. Alternative treatment options are currently being developed in order to face the inadequacy of current practices. In this review, pathologies and current treatments of gynecological organs (ovaries, uterus, and vagina) will be described. The state-of-the-art of tissue engineering alternatives to common practices are evaluated with a focus on in vivo models. Tissue engineering is an ever-expanding field, integrating various domains of modern science to create sophisticated tissue substitutes in the hopes of repairing or replacing dysfunctional organs using autologous cells. Application to gynecology has the potential of restoring female fertility and sexual wellbeing.

show abstract

Bioethical issues and legal frameworks of surrogacy: A global perspective about the right to health and dignity

Cited by 20 publications

References 89 publications

Tissue Engineering in Gynecology

Tissue Engineering in Gynecology

Pancreatic transplant surgery and stem cell therapy: Finding the balance between therapeutic advances and ethical principles

Tissue Engineering in Gynecology

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