Bioethical framework for the implementation of antimicrobial resistance control in Indonesia: a research protocol (Preprint)

Abstract

BACKGROUND Bioethics is an important aspect of theory and practice in biomedical sciences. Antimicrobial resistance is a global health issue that has inhibiting and supporting factors in its prevention strategy. The implementation of antimicrobial resistance control program in hospitals has been implemented. There are no data showing that bioethics is used as a principle in the implementation of antimicrobial resistance control program. In addition, there is no standardized bioethical framework to support the implementation of the antimicrobial resistance control program. OBJECTIVE This research protocol describes a conceptual model of a series of studies with the main objectives to develop a bioethical framework for the use of antibiotics and to design strategies to protect the public from the threat of antimicrobial resistance in hospital environments in Indonesia. METHODS Qualitative method approach will be applied to achieve the main objectives of this project. Five sub-studies will also be carried out in the form of literature review and field study. RESULTS A scoping review study is underway to see the implementation of antimicrobial resistance prevention based on bioethics principle. Data collection begin in April 2022. 773 articles identified through PubMed, Embase, ScienceDirect, Google Scholar, ProQuest and EBSCO. The search results from six databases will be included in the elimination process based on the inclusion and exclusion criteria. CONCLUSIONS Bioethical framework will be developed for control the use of antibiotics as well as designing strategies to protect the public from the threat of antimicrobial resistance in the hospital environment. The framework will be developed based on data collection, future findings and using a comprehensive, integrative and evidence-based approach.