Biodegradation of the endocrine disrupter 4-tert-octylphenol by the yeast strain Candida rugopelliculosa RRKY5 via phenolic ring hydroxylation and alkyl chain oxidation pathways

Rajendran, Ranjith; Huang, Shir Ly; Lin, Cheng-Ju; Kirschner, Roland

doi:10.1016/j.biortech.2016.11.129

Cited by 34 publications

(15 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The range of concentrations of the two chemical compounds suggested that the two pollutants were not always present in the river water. They could have been partly removed by the water treatment plants located along the course of the river and possibly in addition to (bio)degradation through biological or/and by physical process (Rajendran et al 2017 ). The average concentrations of both compounds were highest in 2016 winter, brought about by certain anthropogenic activities which were non-existent in 2017.…”

Section: Discussionmentioning

confidence: 99%

Determination and ecological risk assessment of two endocrine disruptors from River Buffalo, South Africa

Olaniyan

Okoh

2020

Environ Monit Assess

View full text Add to dashboard Cite

4-tert-Octylphenol (4-tOP) and triclosan (TCS) are endocrine disruptors which have been detected in environmental matrices such as air, soil and water at ultra-low levels. Exposure to endocrine disruptors may account at least in part, for the global increase in the incidence of non-communicable diseases like cancers and diabetes and may also lead to an imbalance in the aquatic ecosystem. River Buffalo is an important natural resource in the Eastern Cape of South Africa serving more than half a million people. The presence of the two compounds in the river water hitherto unknown was investigated during winter seasons using solid-phase extraction and gas chromatography–mass spectrometric techniques. The sampling points differed by some physicochemical parameters. The concentration of 4-tOP ranged 0–755 ng/L, median value 88.1 ng/L while that of TCS ranged 0–1264.2 ng/L and the median value was 82.1 ng/L. Hazard quotient as an index of exposure risk varied according to daphnids ˃ fish ˃ algae for 4-tOP exposure while HQ for TCS exposure was algae > daphnids = fish showing that both compounds were capable of causing imbalance in the aquatic ecosystem.

show abstract

Section: Discussionmentioning

confidence: 99%

Determination and ecological risk assessment of two endocrine disruptors from River Buffalo, South Africa

Olaniyan

Okoh

2020

Environ Monit Assess

View full text Add to dashboard Cite

show abstract

“…For cyclic and branched alkanes, such as isooctane and cyclohexane, bacterial assimilation is initiated by hydroxylation, which in turn is catalyzed by P450 enzymes [58][59][60]. Moreover, the assimilation of cyclohexane by C. maltose and isooctane by C. rugopelliculosa is documented [61,62], but without any consideration of the corresponding metabolic pathways or enzymes. In yeasts, CYP52 genes have been directly connected to the degradation of alkanes, but the three K. ohmeri strains presently tested were able to grow with isooctane, 2,2-dimethylbutane, and cycloheptane.…”

Section: Discussionmentioning

confidence: 99%

Candida pseudoglaebosa and Kodamaea ohmeri are capable of degrading alkanes in the presence of heavy metals

et al. 2019

View full text Add to dashboard Cite

The aim of this study was to examine four strains of two yeast species in relation to their capability for assimilating alkanes in the presence of heavy metals (HMs). The four strains tested were Candida pseudoglaebosa ENCB‐7 and Kodamaea ohmeri ENCB‐8R, ENCB‐23, and ENCB‐VIK. Determination was made of the expression of CYP52 genes involved in alkane hydroxylation. When exposed to Cu2+, Zn2+, Pb2+, Cd2+, and As3+ at pH 3 and 5, all four strains could assimilate several n‐alkanes having at least six carbon atoms. The three K. ohmeri strains could also utilize branched alkanes, cycloalkanes, and n‐octanol as sole carbon sources. Kinetic assays demonstrated greater biomass production and specific growth of the yeasts exposed to long‐chain n‐alkanes. Fragments of paralogous CYP52 genes of C. pseudoglaebosa ENCB‐7 and K. ohmeri ENCB‐23 were amplified, sequenced, and phylogenetically evaluated. Reverse‐transcription polymerase chain reaction revealed that n‐nonane and n‐decane induced to CpCYP52‐G3, CpCYP52‐G9, and CpCYP52‐G10. KoCYP52‐G3 was induced with n‐decane and n‐octanol. Also, CpCYP52‐G3 and CpCYP52‐G9 were induced by glucose. In conclusion, C. pseudoglaebosa and K. ohmeri were able to degrade several alkanes in the presence of HMs and under acidic conditions. These yeasts harbor paralogous alkane‐induced CYP52 genes, which display different profiles of transcriptional expression.

show abstract

“…Additionally, the strain RRK20 is capable of utilizing a variety of EDCs, including alkylphenol polyethoxylates, alkylphenols and natural and synthetic estrogens. The yeast Candida rugopelliculosa RRKY5 [63] was proved to be able to utilize a variety of substances, such as 4-methylphenol, BPA and phenol, under aerobic conditions. Moreover, the degradation mechanisms of 4-t-OP by the strain RRKY5 were by both the branched alkyl side chain and aromatic ring.…”

Section: Biodegradation Of Edcsmentioning

confidence: 99%

Environment-Friendly Removal Methods for Endocrine Disrupting Chemicals

et al. 2020

View full text Add to dashboard Cite

In the past few decades, many emerging pollutants have been detected and monitored in different water sources because of their universal consumption and improper disposal. Among these, endocrine-disrupting chemicals (EDCs), a group of organic chemicals, have received global attention due to their estrogen effect, toxicity, persistence and bioaccumulation. For the removal of EDCs, conventional wastewater treatment methods include flocculation, precipitation, adsorption, etc. However, there are some limitations on these common methods. Herein, in order to enhance the public’s understanding of environmental EDCs, the definition of EDCs and the characteristics of several typical EDCs (physical and chemical properties, sources, usage, concentrations in the environment) are reviewed and summarized in this paper. In particular, the methods of EDC removal are reviewed, including the traditional methods of EDC removal, photocatalysis, biodegradation of EDCs and the latest research results of EDC removal. It is proposed that photocatalysis and biodegradation could be used as an environmentally friendly and efficient EDC removal technology. Photocatalytic technology could be one of the water treatment methods with the most potential, with great development prospects due to its high catalytic efficiency and low energy consumption. Biodegradation is expected to replace traditional water treatment methods and is also considered to be a highly promising method for efficient removal of EDCs. Besides, we summarize several photocatalysts with high catalytic activity and some fungi, bacteria and algae with strong biodegradability.

show abstract

Biodegradation of the endocrine disrupter 4-tert-octylphenol by the yeast strain Candida rugopelliculosa RRKY5 via phenolic ring hydroxylation and alkyl chain oxidation pathways

Cited by 34 publications

References 41 publications

Determination and ecological risk assessment of two endocrine disruptors from River Buffalo, South Africa

Determination and ecological risk assessment of two endocrine disruptors from River Buffalo, South Africa

Candida pseudoglaebosa and Kodamaea ohmeri are capable of degrading alkanes in the presence of heavy metals

Environment-Friendly Removal Methods for Endocrine Disrupting Chemicals

Contact Info

Product

Resources

About