Biodegradation behavior of micro-arc oxidation coating on magnesium alloy-from a protein perspective

Zhang, Zhao-Qi; Wang, Li; Zeng, Mei-Qi; Zeng, Rong‐Chang; Kannan, M. Bobby; Lin, Cunguo; Zheng, Yufeng

doi:10.1016/j.bioactmat.2020.03.005

Cited by 102 publications

(37 citation statements)

References 66 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Currently, Mg and its alloys have been widely used in bone implant materials, and the degradable Mg bone nail developed by Yian Technology Co., Ltd. has been officially certified by Conformite Europeenne (CE). Moreover, Mg alloys are a promising material for cardiovascular stents because of their high elastic modulus, fine mechanical characteristics, and biodegradability [ 10 , [31] , [32] , [33] , [34] ]. Mg-based stents have potential advantages over polymeric stents in terms of higher radial strength due to their metallic nature and biocompatibility as a naturally occurring element in the body.…”

Section: Introductionmentioning

confidence: 99%

Advances in coatings on magnesium alloys for cardiovascular stents – A review

Zhang

Yang

et al. 2021

Bioactive Materials

Self Cite

105

View full text Add to dashboard Cite

Magnesium (Mg) and its alloys, as potential biodegradable materials, have drawn wide attention in the cardiovascular stent field because of their appropriate mechanical properties and biocompatibility. Nevertheless, the occurrence of thrombosis, inflammation, and restenosis of implanted Mg alloy stents caused by their poor corrosion resistance and insufficient endothelialization restrains their anticipated clinical applications. Numerous surface treatment tactics have mainly striven to modify the Mg alloy for inhibiting its degradation rate and enduing it with biological functionality. This review focuses on highlighting and summarizing the latest research progress in functionalized coatings on Mg alloys for cardiovascular stents over the last decade, regarding preparation strategies for metal oxide, metal hydroxide, inorganic nonmetallic, polymer, and their composite coatings; and the performance of these strategies in regulating degradation behavior and biofunction. Potential research direction is also concisely discussed to help guide biological functionalized strategies and inspire further innovations. It is hoped that this review can give assistance to the surface modification of cardiovascular Mg-based stents and promote future advancements in this emerging research field.

show abstract

Section: Introductionmentioning

confidence: 99%

Advances in coatings on magnesium alloys for cardiovascular stents – A review

Zhang

Yang

et al. 2021

Bioactive Materials

Self Cite

105

View full text Add to dashboard Cite

show abstract

“…In these equivalent circuit models, R s is the solution resistance, DCPD coating and surface oxide film are related to a coating resistance ( R c ) (virtual pore resistance) paralleled with a constant phase element ( Q c ), and substrate-coating interface reaction is represented by the charge transfer resistance ( R ct ) paralleled with a double-layer constant phase element ( Q dl ). Besides, the inductive behavior is corresponding to the resistance ( R L ) in series with an inductance ( L ), indicating the initiation of pitting corrosion [ 40 ]. EIS plots for Mg plates in Hank's and NS solutions consist of similar capacitive loops, which can be fitted by the equivalent circuit model in Fig.…”

Section: Resultsmentioning

confidence: 99%

Insights into self-healing behavior and mechanism of dicalcium phosphate dihydrate coating on biomedical Mg

Dong

Zhou

Feng

et al. 2021

Bioactive Materials

View full text Add to dashboard Cite

Self-healing coatings have been developed as smart surface coatings for Mg and its alloys to retain local corrosion from the coating damages. In this study, we prepared dicalcium phosphate dihydrate (DCPD) coating on biomedical Mg, and found that the artificial scratches in DCPD coating can be efficiently sealed by anti-corrosive products in both Hank's and normal saline (NS) solutions. Besides, the in-depth study revealed that DCPD was served as not only a physical barrier but also a self-healing agent, demonstrating an autonomous self-healing coating without embedded extra corrosion inhibitors. Moreover, Hank's solution provided foreign-aid film-forming ions to promote self-healing behavior. The findings might offer new opportunities for further studies and applications of efficient self-healing coatings on biodegradable Mg implants.

show abstract

“…By way of illustration, a large number of polymer coatings have been used to protect Mg biomaterials against corrosion, yield diverse functional properties, and enhance biocompatibility, such as, polycaprolactone, poly(lactic‐co‐glycolic) acid, polylactic acid, polydopamine, collagen, and chitosan, 171 although polymer coatings exhibit poor adhesion to the metal substrate. On the other side, micro‐arc oxidation coatings suffer from micropores and cracks, which severely limit their corrosion protection ability 172 . Therefore, recent research suggests that designers produce a duplex coating including an inner film of micro‐arc oxidation coating followed by polymer deposition coating, as the top layer on the surface of micro‐arc oxidation coating, thereby overcoming the limitations of MAO and polymer coatings 173–175 .…”

Section: Opportunities To Overcome the Current Challengesmentioning

confidence: 99%

Biodegradable magnesium‐based biomaterials: An overview of challenges and opportunities

Amukarimi

Mozafari

2021

MedComm

108

View full text Add to dashboard Cite

As promising biodegradable materials with nontoxic degradation products, magnesium (Mg) and its alloys have received more and more attention in the biomedical field very recently. Having excellent biocompatibility and unique mechanical properties, magnesium‐based alloys currently cover a broad range of applications in the biomedical field. The use of Mg‐based biomedical devices eliminates the need for biomaterial removal surgery after the healing process and reduces adverse effects induced by the implantation of permanent biomaterials. However, the high corrosion rate of Mg‐based implants leads to unexpected degradation, structural failure, hydrogen evolution, alkalization, and cytotoxicity. To overcome these limitations, alloying Mg with suitable alloying elements and surface treatment come highly recommended. In this area, open questions remain on the behavior of Mg‐based biomaterials in the human body and the effects of different factors that have resulted in these challenges. In addition to that, many techniques are yet to be verified to turn these challenges into opportunities. Accordingly, this article aims to review major challenges and opportunities for Mg‐based biomaterials to minimize the challenges for the development of novel biomaterials made of Mg and its alloys.

show abstract

Biodegradation behavior of micro-arc oxidation coating on magnesium alloy-from a protein perspective

Cited by 102 publications

References 66 publications

Advances in coatings on magnesium alloys for cardiovascular stents – A review

Advances in coatings on magnesium alloys for cardiovascular stents – A review

Insights into self-healing behavior and mechanism of dicalcium phosphate dihydrate coating on biomedical Mg

Biodegradable magnesium‐based biomaterials: An overview of challenges and opportunities

Contact Info

Product

Resources

About