Biodegradability of the Krupin-Denver Valve

Ormerod, L. David; Pickford, Michael; Baerveldt, George

doi:10.1016/0002-9394(88)90254-1

Cited by 3 publications

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Pre vious studies [1][2][3][4][5][6][7][8][9] have clearly shown the advantages of Krupin-Denver valve implantation in glaucoma surgery as well as the main complications and causes o f failure: hypotony in the early postoperative period, blockage of the in ternal fistula, blockage of the external fistula. Long-term results of Krupin-Denver valve implantation are often con-ditioned by the high mortality of patients [3].…”

Section: Introductionmentioning

confidence: 99%

Long-Term Results of Krupin-Denver Valve Implants in Filtering Surgery for Neovascular Glaucoma

Mastropasqua

Carpineto²,

Ciancaglini³

et al. 1996

Ophthalmologica

View full text Add to dashboard Cite

The long-term results obtained with the Krupin eye short valve shunt in 28 eyes with neovascular glaucoma were retrospectively analyzed by means of Kaplan-Meier survival curve. The preoperative intraocular pressures (IOPs) ranged from 28 to 62 mm Hg (mean, 36.8 ± 5.8 mm Hg). Success was considered an IOP of less than 22 mm Hg and greater than 5 mm Hg without medication (complete success) or with medication (qualified success) without additional glaucoma filtering surgery or devastating complications. Postoperative success was obtained in 10 out of 28 eyes after a mean follow-up period of 58.4+23.02 months (range, 10-108 months). The 3- and 6-year life table success rates were 66 and 34%, respectively. Early complications were: shallow or flat anterior chamber (15 patients, 53.6%), hypotony (16 patients, 57.1%), hypertony (7 patients, 25%), serous choroidal effusion (7 patients, 25%), fibrinous uveitis (5 patients, 17.9%), blockage of the intracameral portion of the tube by fibrin (5 patients, 17.9%), choroidal hemorrhage (2 patients, 7.1%). Late complications were: external conjunctival bleb failure (12 patients, 42.9%), blockage of the intracameral portion of the tube by fÍbrovascular tissue (5 patients, 17.9%), cataract (2 patients, 7.1%), bullous keratopathy (2 patients, 7.1%), external erosion of the Silastic valve (2 patients, 7.1%), phthisis bulbi (2 patients, 7.1%). Mortality during long-term follow-up was high in our series. The complications of an underlying diabetes mellitus were the most common causes of death (15 out of 22 patients). The high mortality of patients subjected to valve implantation makes it difficult to interpret the results of long-term studies. However, the valve implant is still today an alternative surgical procedure for controlling IOP in eyes with neovascular glaucoma that have visual potential.

show abstract