Biocompatible magnetic core/shell nanoparticles

Goetze, T.; Gansau, C.; Buske, N.; Roeder, Manuel; Görnert, P.; Bähr, M.

doi:10.1016/s0304-8853(02)00624-8

Cited by 78 publications

(47 citation statements)

References 7 publications

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“…Peptization of the precipitated magnetic nanoparticle as ionic MF can be accomplished in low-pH as well as in high-pH values [26,27]. Fresh precipitate containing magnetic nanoparticle can be suspended in both non-polar [28,29] and polar-based media [30,31]. Starting with MF samples magnetic nanosized particles can be encapsulated as anionic of cationic magnetoliposome (ML), trapped in magnetic nanoemulsion (MNE) or hosted in magnetic nanocapsule (MNC).…”

Section: The Materials Platform Provided By Nanosized Magnetic Particlesmentioning

confidence: 99%

Nanoparticulated magnetic drug delivery systems: Preparation and magnetic characterization

Morais¹

2010

J. Phys.: Conf. Ser.

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Section: The Materials Platform Provided By Nanosized Magnetic Particlesmentioning

confidence: 99%

Nanoparticulated magnetic drug delivery systems: Preparation and magnetic characterization

Morais¹

2010

J. Phys.: Conf. Ser.

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“…The drug release is controlled by the properties of the polymer-drug systems and to some extent environmental factors such as pH, enzymes and inter-patient variance [1][2] . Despite several advantages offered by controlled drug release, a major problem associated with all doi:10.5138/ ijdd.2010.0975.0215.03059 ©arjournals.org, All rights reserved.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Magnetic Methyl Methacrylate Microspheres Loaded with Indomethacin by Emulsion Solvent Evaporation Technique.

Varma¹,

Amareshwar²,

Devara³

2011

Int J Drug Del

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Magnetic nanoparticles encapsulated in Methyl methacrylate (Eudragit L-100) microspheres containing Indomethacin drug were prepared and their detailed structural and magnetic characteristics were studied. Iron oxide nanoparticles were obtained by chemical coprecipitation of Fe(II) and Fe(III) salts and stabilized with tetra-methyl ammonium hydroxide. Microspheres were prepared by solvent evaporation technique. We characterized the magnetic microspheres in terms of morphology, composite microstructure, size and size distribution, magnetic properties and in-vitro release patterns. The microspheres were uniform both in shape and usually also in size; their size distribution was narrow. All the magnetic parameters confirm superparamagnetic nature of the microspheres with magnetizations up to 20-30 emu/g of microspheres. The in-vitro release profile was studied in pH 7.4 phosphate buffer medium up to 8 hours using USP XXII dissolution apparatus. Drug release in the first hour was found to increase and reached a maximum, releasing approximately 60-85% of the total drug content from the microspheres within 8 hours. From this study, it could be suggested that magnetic Methyl methacrylate microspheres could be retained at their target site invivo and such microspheres can be used in biomedical applications and research areas such as target drug delivery, selective blood detoxification, tissue engineering and replacement, and magnetic resonance imaging (MRI) contrast agents.

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“…The characterization of the modified nano sized magnetic iron *Corresponding author. E-mail: kassaeem@modares.ac.ir oxide particles by various techniques is described [23]. Recently, the possibility of human nervous system to exchange information with electronic devices is studied [24].…”

Section: Introductionmentioning

confidence: 99%

Nano iron oxide with the neural-network morphology

Kassaee

Ghavami

Cheshmehkani

et al. 2009

JICS

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To improve network-functioning, an arc discharge method was developed for the synthesis of nano iron oxide with "neuralnetwork" morphology. Iron wires with diameters of 0.01-0.05 cm were subjected to currents of 50-200 A, until explosions occured in the open air. The XRD and RAMAN spectra of the as-prepared-products indicate formation of nano-Fe 2 O 3 (tetragonal and monoclinic) crystals. Their SEM images show fabrication of nano iron oxide with three different morphologies: spheres, chains, and a "neural-network" biological form. While the latter is unprecedented, our fabrications of nano iron oxide with both sphere and chain morphologies are reproductions of previously reported results. The sphere shaped nanoparticles show a uniform distribution with sizes in the range of 50-250 nm. The specifications of the chain nano products appear consistent with those reported.

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Biocompatible magnetic core/shell nanoparticles

Cited by 78 publications

References 7 publications

Nanoparticulated magnetic drug delivery systems: Preparation and magnetic characterization

Nanoparticulated magnetic drug delivery systems: Preparation and magnetic characterization

Synthesis and Characterization of Magnetic Methyl Methacrylate Microspheres Loaded with Indomethacin by Emulsion Solvent Evaporation Technique.

Nano iron oxide with the neural-network morphology

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