Biocompatible electrospun tactic poly(methyl methacrylate) blend fibers

Sharma, Jaishri; Zhang, Xi; Sarker, Tanusree; Yan, Xingru; Washburn, Lauren; Qu, Honglin; Guo, Zhanhu; Kucknoor, Ashwinin; Wei, Suying

doi:10.1016/j.polymer.2014.05.028

Cited by 16 publications

(17 citation statements)

References 77 publications

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“…[21][22][23][24][25][26][27] ZnO is an environmentally friendly, important and attractive semiconducting material. It has drawn enormous research attention due to its distinguished properties in optics, photonics and electronics.…”

Section: Introductionmentioning

confidence: 99%

Effect of ZnO on the Thermal Degradation Behavior of Poly(Methyl Methacrylate) Nanocomposites

Japić

Marinšek

Orel

2016

ACSi

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In the memory of Janez (Janko) Jamnik our dear friend and co-worker. AbstractThe influence of ZnO nanoparticles on the thermal degradation behavior of poly(methyl methacrylate) (PMMA) was tested using thermoanalytical techniques. The studied materials were investigated using TG, DTA, EGA, XRD, SEM and TEM. The ZnO nanoparticles were synthesized via precipitation by adding LiOH into Zn 2+ water/ethylene glycol solutions. The ZnO-PMMA nanocomposites were prepared by adding the appropriate amount of ZnO into MMA and subsequent MMA radical polymerization. According to the experimental results and model-free isoconversional activation energy calculations, the addition of ZnO into PMMA played a double role. The ZnO concentrations up to 0.15% stabilized the composite by shifting the degradation interval toward higher temperatures and increasing the apparent activation energy relative to pure PMMA. At higher concentrations, the catalytic effect of ZnO started to prevail and was reflected in the lower temperature intervals of intense PMMA degradation and lower apparent activation energy. The addition of ZnO generally did not change the nature of the PMMA decomposition process.

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Section: Introductionmentioning

confidence: 99%

Effect of ZnO on the Thermal Degradation Behavior of Poly(Methyl Methacrylate) Nanocomposites

Japić

Marinšek

Orel

2016

ACSi

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“…[1][2][3][4][5] The working fluid 20 in a traditional single fluid electrospinning process is often a mixed solution of an active ingredient and a filament-forming polymer; suspensions of functional nanoparticles may also be used. [6][7][8][9][10] The active ingredient must have sufficient solubility in the chosen solvent to give an effective therapeutic dose in the 25 patient.…”

Section: Introductionmentioning

confidence: 99%

Electrospun acid–base pair solid dispersions of quercetin

Yan

et al. 2014

RSC Adv.

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An electrospun acid-base pair solid dispersion in the form of core-shell nanofibers was developed for improving the dissolution of quercetin (8 cm× 4 cm, 600 dpi)In this work, electrospinning was used to fabricate core-shell nanofibers containing acid-base pairs. Quercetin was used as a model active ingredient. To exploit its solubility in basic conditions, a solution of quercetin, polyvinylpyrrolidone (PVP) and sodium hydroxide was used as the core fluid, and one consisting of citric acid and PVP as the shell fluid. Scanning and transmission electron microscopy demonstrated that core-shell nanofibers with linear morphologies were obtained, without beads or 10 spindles. X-ray diffraction showed that quercetin was present in the fibers in an amorphous state; Fourier transform infrared spectroscopy indicated this may be a result of hydrogen bonding between the drug and the polymer matrix. In in vitro dissolution tests the drug was found to be released immediately when the fibers encountered an aqeuous medium. There was no change in the pH of the medium after dissolution, as a result of the presence of the acid-base pair. This provides a new strategy for improving the 15 dissolution behavior of poorly water-soluble drugs using polymeric nanostructures.

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“…Biologically active substances can be attached to nanofibers like a mesh in the electrospinning process. In this way, antibacterial and antioxidant materials are created for medical applications [103,104]. Coating materials containing chitosan formulations with antioxidant and antifungal properties were also formed [88,105].…”

Section: Electrospun Antioxidant/antibacterial Materials For Medicmentioning

confidence: 99%

“…Scientific research has proven the antibacterial activity of electrospun nanofibers containing polylactic acid and silver nanoparticles (AgNPs) against Staphylococcus aureus and Escherichia coli . Fibers of silver nanoparticles and polyethylene oxide were mixed with polyurethane fibers exhibiting antibacterial activity on Escherichia coli [103,105]. Antimicrobial efficacy increases with an increase in the concentration of silver.…”

Section: Electrospun Antioxidant/antibacterial Materials For Medicmentioning

confidence: 99%

Biopolymers for Biomedical and Pharmaceutical Applications: Recent Advances and Overview of Alginate Electrospinning

et al. 2019

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Innovative solutions using biopolymer-based materials made of several constituents seems to be particularly attractive for packaging in biomedical and pharmaceutical applications. In this direction, some progress has been made in extending use of the electrospinning process towards fiber formation based on biopolymers and organic compounds for the preparation of novel packaging materials. Electrospinning can be used to create nanofiber mats characterized by high purity of the material, which can be used to create active and modern biomedical and pharmaceutical packaging. Intelligent medical and biomedical packaging with the use of polymers is a broadly and rapidly growing field of interest for industries and academia. Among various polymers, alginate has found many applications in the food sector, biomedicine, and packaging. For example, in drug delivery systems, a mesh made of nanofibres produced by the electrospinning method is highly desired. Electrospinning for biomedicine is based on the use of biopolymers and natural substances, along with the combination of drugs (such as naproxen, sulfikoxazol) and essential oils with antibacterial properties (such as tocopherol, eugenol). This is a striking method due to the ability of producing nanoscale materials and structures of exceptional quality, allowing the substances to be encapsulated and the drugs/ biologically active substances placed on polymer nanofibers. So, in this article we briefly summarize the recent advances on electrospinning of biopolymers with particular emphasis on usage of Alginate for biomedical and pharmaceutical applications.

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Biocompatible electrospun tactic poly(methyl methacrylate) blend fibers

Cited by 16 publications

References 77 publications

Effect of ZnO on the Thermal Degradation Behavior of Poly(Methyl Methacrylate) Nanocomposites

Effect of ZnO on the Thermal Degradation Behavior of Poly(Methyl Methacrylate) Nanocomposites

Electrospun acid–base pair solid dispersions of quercetin

Biopolymers for Biomedical and Pharmaceutical Applications: Recent Advances and Overview of Alginate Electrospinning

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