2001
DOI: 10.1007/s002400000166
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Biocompatibility of silver nitrate and ofloxacine coated bioabsorbable SR-PLLA rods

Abstract: The purpose of this study was to evaluate the biocompatibility of silver nitrate and ofloxacine coatings of bioresorbable self-reinforced poly-L-lactic acid (SR-PLLA) rods. SR-PLLA rods coated with pure poly(caprolactone-co-L-lactide) or blended with silver nitrate (10, 5 or 2 weight-%) or ofloxacine (5 or 2 weight-%) were implanted in the dorsal muscles of 25 male rabbits. Tissue reactions caused by implantation trauma were seen 1 week after implantation. The positive control and 10 w-% silver nitrate coating… Show more

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Cited by 6 publications
(3 citation statements)
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“…397 Polyester-type waterborne PU containing up to 3 × 10 4 ppb (3 × 10 4 μg kg ). 480 Recently, Qureshi et al 358 confirmed that the AgNP-PLLA nanocomposite films with a AgNP concentration of 7 × 10 5 ppb (7 × 10 5 μg kg…”
Section: Bloodmentioning
confidence: 99%
See 1 more Smart Citation
“…397 Polyester-type waterborne PU containing up to 3 × 10 4 ppb (3 × 10 4 μg kg ). 480 Recently, Qureshi et al 358 confirmed that the AgNP-PLLA nanocomposite films with a AgNP concentration of 7 × 10 5 ppb (7 × 10 5 μg kg…”
Section: Bloodmentioning
confidence: 99%
“…Another polymer, PLLA, was shown to remain biocompatible in vivo with a coating containing up to 5 wt % AgNO 3 (5 × 10 7 μg kg −1 ). 480 Recently, Qureshi et al 358 confirmed that the AgNP-PLLA nanocomposite films with a AgNP concentration of 7 × 10 5 ppb (7 × 10 5 μg kg −1 ) had little effect on the viability of human HeLa cells (see also section 4.1.3). In addition, silvercoated polypropylene mesh used in a rat abdominal model 481 has shown in vitro and in vivo combined antibacterial efficacy with a good biocompatibility as well as tissue integration.…”
Section: Blood Contact: Implants Introduced Into Thementioning
confidence: 99%
“…Ha sido utilizado en el tratamiento médico del aparato respiratorio (25), aparato reproductor (26), para el tratamiento sintomático de aftasde la mucosa oral (4,5), y antiguamente para la hipersensibilidad dentinaria (6,7). Su biocompatibilidad (27,28), potencial alergénico (29) y efecto antibacteriano (30) son favorables para su utilización en el ámbito médico.…”
Section: Discussionunclassified