Biocompatibility evaluation of DLC-coated Si3N4 substrates for biomedical applications

Salgueiredo, E.; Vila, M.; Silva, M.A.; Lopes, M. A.; Santos, J. D.; Costa, F.M.; Silva, R.F.; Gomes, Pedro S.; Fernandes, Maria Helena

doi:10.1016/j.diamond.2007.08.019

Cited by 77 publications

(34 citation statements)

References 14 publications

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“…Some significant researches about zirconia such as developing stabilized zirconia, inducing bioactivity by chemical treatments and improving the surface hard have been conducted [58][59][60]. Silicon nitride (Si 3 N 4 ) [61][62][63][64] and Silicon carbide (SiC) [65][66][67][68][69] are also two kinds frequently used biomedical materials for their good performances.…”

Section: Metallic and Ceramic Biomedical Materialsmentioning

confidence: 99%

The recent progress of tribological biomaterials

Shi

Guo

Liu

2015

Biosurface and Biotribology

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Tribological phenomena abundantly exist in living beings, especially in human beings, such as teeth, eyes, bones, skins, heart valves and so on, and it is of meanings to reveal the mechanism of tribology in human body and fabricate artificial biomaterials to replace the damaged tissues to release the pain of patients. Alloys, ceramics and polymers are three uppermost materials used in engineering and some of them play a crucial role in biomedicine. In the paper, we provide an overview of the tribological behaviors of artificial biomaterials including alloys, ceramics and polymers. We aim to provide fundamental mechanistic and applications of tribological biomaterials, while emphasizing the advantages and disadvantages of various kinds of tribological biomaterials. Finally, some challenges and the potential promising breakthroughs are also succinctly highlighted in this field.

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Section: Metallic and Ceramic Biomedical Materialsmentioning

confidence: 99%

The recent progress of tribological biomaterials

Shi

Guo

Liu

2015

Biosurface and Biotribology

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“…Finally, once having obtained the prototypes in end materials different surface deposits can be used by means of physical or chemical steam deposition technologies (particularly the new DLC ''diamond like carbon'') coatings, as well as textile coatings to ensure the biocompatibility of the device and facilitate its implantation. 36 In whichever case, in order to optimize the safety of the personalized devices produced and make it easier to apply them, it is mandatory to meet the guidelines of the ''European Directive on Medical Devices-93/42/EEC''. It is also advisable to follow the recommendations of ISO Standard 13485 on the quality of medical devices, as well as specific regulations on material characterization testing (ISO and ASTM Standards).…”

Section: Rapid Prototype Manufacturementioning

confidence: 99%

Development of Personalized Annuloplasty Rings: Combination of CT Images and CAD-CAM Tools

et al. 2009

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Although the use of personalized annuloplasty rings manufactured for each patient according to the size and morphology of their valve complex could be beneficial for the treatment of mitral insufficiency, this possibility has been limited for reasons of time-lines and costs as well as for design and manufacturing difficulties, as has been the case with other personalized implant and prosthetic developments. However, the present quality of medical image capture equipment together with the benefits to be had from computer-aided design and manufacturing technologies (CAD-CAM) and the capabilities furnished by rapid prototyping technologies, present new opportunities for a personalized response to the development of implants and prostheses, the social impact of which could turn out to be highly positive. This paper sets out a personalized development of an annuloplasty ring based on the combined use of information from medical imaging, from CAD-CAM design programs and prototype manufacture using rapid prototyping technologies.

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“…Definitive version available on ScienceDirect. Also at http://dx.doi.org/10.1016/j.diamond.2010.02.012 [7,[14][15][16]. Klages et al [10] demonstrate efficacy of a-C:Si:H films as a diffusion barrier, and Maguire et al [15], in their investigation of DLC coated stents and guidewires, show that doping the DLC with silicon further minimises film cracking and significantly improves corrosion resistance.…”

Section: Jones Et Al Diamond-like Carbon Coating Of Alternative Metamentioning

confidence: 99%

“…The risk of any adverse effects related to aluminium biocompatibility could potentially be overcome by coating the instruments with a diffusion barrier. Diamond-like carbon (DLC) has demonstrated biocompatibility [6] and has been shown to be effective as a diffusion barrier, including for biomedical implants such as cardiovascular stents, heart valves and orthopaedic devices [7][8][9][10]. In addition to the barrier properties to prevent corrosion and leaching of aluminium to biological tissue, the damage resistance of the coating is also important in the clinical environment to counter wear and tear from normal operation and cleaning procedures.…”

Section: Introductionmentioning

confidence: 99%

Diamond-like carbon coating of alternative metal alloys for medical and surgical applications

Jones

Mahendran

Anson

et al. 2010

Diamond and Related Materials

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The effectiveness of a plasma-deposited, diamond-like carbon (DLC) coating on aluminium alloy based surgical instruments is investigated. Surgical instruments must satisfy a number of important criteria including biocompatibility, functional performance, sterility and cleanability, structural integrity, and fatigue resistance. The integrity of the DLC layer and the diffusion barrier properties are of paramount importance due to biocompatibility considerations of the underlying aluminium metal. We investigate optimisation of the coating with incorporation of silicon and variation in negative self bias, and highlight the design and manufacture of a lightweight laparoscopic assist instrument from aluminium alloy coated with diamond-like carbon, which has been used successfully in the clinical environment to improve operations such as cholecystectomy (gall bladder removal) and exploratory techniques for the diagnosis of cancer.

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Biocompatibility evaluation of DLC-coated Si3N4 substrates for biomedical applications

Cited by 77 publications

References 14 publications

The recent progress of tribological biomaterials

The recent progress of tribological biomaterials

Development of Personalized Annuloplasty Rings: Combination of CT Images and CAD-CAM Tools

Diamond-like carbon coating of alternative metal alloys for medical and surgical applications

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