Biochemistry Subject Collections: An Introduction

Schlessinger, Bernard S.

doi:10.4324/9781003002994-1

Cited by 10 publications

(14 citation statements)

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“…In forward auditory input pathway auditory signals In the backward auditory input pathway of sound, there is a high possibility that Melanocytes and Neuromelanin pass the auditory information through Gap Junctions [107]. In Utricle and Saccule the auditory information will be separated from Vestibular information and the auditory information from two different directions (forward auditory input pathway and backward auditory input pathways) will be combined and eventually the combined information will be delivered it to the cochlea [100][101][102][103][104][105][106]. Melanin and pigmented cells have been observed around the Round Window Membrane (RW) [108].…”

Section: Discussionmentioning

confidence: 99%

The Link Between Brain and Auditory System and Possible Role of Vestibular System in Hearing System as a Second Middle Ear and the Role of Melanocytes and/or Neuromelanin in this Process

Bina¹

2021

ANN

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Section: Discussionmentioning

confidence: 99%

The Link Between Brain and Auditory System and Possible Role of Vestibular System in Hearing System as a Second Middle Ear and the Role of Melanocytes and/or Neuromelanin in this Process

Bina¹

2021

ANN

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“…In the same way, with a minimal level of the same brown melanin, the eye looks blue. Even though a genetic variation can cause a child's eye colour to be unpredictable, resulting in two blue-eyed parents having a browneyed child [32][33][34]. Overall, blue eyes have been caused by a single recessive gene, and a blue-eyed parent could never produce a brown-eyed child.…”

Section: Literature Reviewmentioning

confidence: 99%

Using mathematical modeling, identify the repetition and progression of the human eye's colour pattern

Ghani

Syed

Leghari

2023

Technium Education and Humanities

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The formation of human eyes is basically a result of genetic mutation process. The colour of eyes is determined by variation of genes which are associated with eye colour to produce transport or storage of a pigment is called melanin. In this research this aspect is confirm with the theory of Jordan algebra which has invented from an associative algebra which is relative to the arrangement, this scheme is called special Jordan algebras. To verifying the eyes colour mutation an appropriate number of datasets are collected from survey and observation, similar result found from the collected datasets which show that, the human eyes colour which is an outcome of genetic mutation of eye genes which appeared in first generation is mostly skip in second generation cycle and same process is repeat in generation to generations. The climate of Pakistan is usually varying in region to region because of temperature its dry and warm near the coastline and low-lying region and gradually cooler in the northern highland’s areas. Mostly in coldest area of Pakistan the colour of eyes are lighter but in some warm areas the lighter eyes colour in eyes colour in eyes causes different types of eyes disease. Lighter eye colour is more sensitive to light because of less amount of melanin. Melanin protects eyes from sun light due to lesser amount of melanin there is chances of macular degeneration (an eye disease that can blur your central vision). The darker coloured eyes practice less visual discomfort in sun light, mean it help in protection from ultraviolet (UV) rays. Lighter coloured of eyes increased the risk of cancer because of less amount of melanin which cannot/less protect eyes from sun light which is very harmful and increase the chance of cancer. Colour vision deficiency, sometime called colour blindness is usually a genetic (hereditary) condition transfer into next generation. Colour blindness is a cause of less melanin ration, the prediction of repetition of eye colour of next generation can be helpful to stop the problem of colour blindness.

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“…The degree of skin pigmentation depends on the degree of gene expression that controls the quality and quantity of melanin (1)(2)(3)(4). Melanin has many physiological benefits in maintaining health, with the most documented being that it acts as a sunscreen and protects the body from harmful ultraviolet (UV) radiation (3,4). Previous studies suggested that melanin may reduce body inflammation, prevent liver injuries and play a role in the immune system (5)(6)(7).…”

Section: Introductionmentioning

confidence: 99%

“…It is naturally produced in the human body and hair follicles, mainly by melanocytes. The degree of skin pigmentation depends on the degree of gene expression that controls the quality and quantity of melanin ( 1 – 4 ). Melanin has many physiological benefits in maintaining health, with the most documented being that it acts as a sunscreen and protects the body from harmful ultraviolet (UV) radiation ( 3 , 4 ).…”

Section: Introductionmentioning

confidence: 99%

Melanin levels in relation to vitamin D among first-generation immigrants from different ethnic groups and origins: A comparative national Canadian cross-sectional study

et al. 2023

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IntroductionImmigrants to Western countries tend to have darker skin than native-born populations. We examined the relationship between skin melanin and serum vitamin D (vitD) [S-25(OH)D] levels and explored whether melanin levels explained S-25(OH)D variations between immigrants and native-born Canadians. This study offers novel findings as no such study has been conducted.MethodsWe used a national cross-sectional population-based design with data from the Canadian Health Measures Survey (CHMS). Skin melanin levels among first-generation immigrants based on their ethnicity and origin/country of birth were compared with white and native-born populations. We assessed the association between S-25(OH)D and melanin after adjusting for independent variables related to S-25(OH)D, melanin level, and immigration status.ResultsOf 11,579 participants, 21.9% were immigrants aged 3–79 years (mean age 39.23 years). Compared with non-immigrants, immigrants had lower S-25(OH)D levels (mean: 51.23 vs. 62.72; 95% CI: 8.37, 14.62; P < 0.001) but higher melanin levels (mean [SE]: 17.08 [0.25] vs. 16.29 [0.29]; 95% CI: −1.29, −0.281; P = 0.004). Melanin did not differ by length of stay in Canada but was weakly positively correlated (r = 0.088, P < 0.001) with S-25(OH)D. Sex (male), age (≥18 years), summer/fall seasons, sunlight exposure, sunscreen non-use, smoking, and alcohol consumption were associated with higher melanin levels, whereas indoor tanning use was not.ConclusionSkin melanin levels were associated with sociodemographic and behavioral characteristics. Immigrants had higher melanin levels, but melanin did not differ by length of stay in Canada. The weak positive correlation between melanin and S-25(OH)D suggested confounding factors may impact the relationship between melanin levels, S-25(OH)D, and immigration status.

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Biochemistry Subject Collections: An Introduction

Cited by 10 publications

References 0 publications

The Link Between Brain and Auditory System and Possible Role of Vestibular System in Hearing System as a Second Middle Ear and the Role of Melanocytes and/or Neuromelanin in this Process

The Link Between Brain and Auditory System and Possible Role of Vestibular System in Hearing System as a Second Middle Ear and the Role of Melanocytes and/or Neuromelanin in this Process

Using mathematical modeling, identify the repetition and progression of the human eye's colour pattern

Melanin levels in relation to vitamin D among first-generation immigrants from different ethnic groups and origins: A comparative national Canadian cross-sectional study

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