Biochemical Responses of Bluegill Sunfish ( Lepomis macrochirus , Rafinesque) to Atrazine Induced Oxidative Stress

Elia, Antonia Concetta; Waller, William T.; Norton, Scott J.

doi:10.1007/s00128-002-0027-4

Cited by 95 publications

(43 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Triazine molecules are able to enhance the concentration of reactive oxygen species (ROS) in fish (Elia et al 2002;Salaberria et al 2009;Jin et al, 2010;Xing et al 2012). Cells develop antioxidant defense system to scavenge the excessive ROS and maintain the redox balance such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and glutathione S-transferase (GST).…”

Section: Introductionmentioning

confidence: 99%

Melamine–cyanurate complexes and oxidative stress markers in trout kidney following melamine and cyanuric acid long-term co-exposure and withdrawal

Pacini

Dörr

Elia

et al. 2014

Fish Physiol Biochem

View full text Add to dashboard Cite

In 2007, renal failure and death in pets were linked to pet food containing both melamine (MEL) and cyanuric acid (CYA). In mammals and fish, the co-administration of MEL and CYA causes renal crystal formation. Moreover, little is known about the process of crystal removal in fish. The aim of this study was to evaluate the formation of MEL-cyanurate crystals in kidney of rainbow trout (Oncorhynchus mykiss) fed combined MEL and CYA diets for 10 weeks at 250, 500 and 1,000 mg/kg in feed (equivalent to 2.5, 5, 10 mg/kg body weight of trout fed 1 % body weight per day). During the exposure trial and throughout a withdrawal period, prooxidant effects of MEL and CYA were evaluated on oxidative stress markers such as catalase, glutathione S-transferase and malondialdehyde. Crystal formation was dose and time dependent, and after six withdrawal weeks, crystals persisted in kidney of trout treated the highest triazine dose. Catalase and glutathione S-transferase activity in kidney of trout exposed to both triazines for 10 weeks indicated that MEL (with or without CYA) can exert a higher prooxidant effect than CYA dispensed singly. Although the enzymes activity increase appears to be reverted after two MEL withdrawal weeks, persistence of crystals may lead to severe damage in renal cells of fish.

show abstract

Section: Introductionmentioning

confidence: 99%

Melamine–cyanurate complexes and oxidative stress markers in trout kidney following melamine and cyanuric acid long-term co-exposure and withdrawal

Pacini

Dörr

Elia

et al. 2014

Fish Physiol Biochem

View full text Add to dashboard Cite

show abstract

“…Pesticides are recognized as serious pollutants in the aquatic environment with the potential to cause deleterious effects on the biota, especially fish (Verma et al, 1982;Elia et al, 2002).…”

mentioning

confidence: 99%

Effects of metribuzin on rainbow trout (Oncorhynchus mykiss)

Velíšek¹,

Svobodová²,

Piačková³

et al. 2008

Vet. Med. - Czech

View full text Add to dashboard Cite

AbstrAct:The aim of this study was to assess the effect of metribuzin on rainbow trout (Oncorhynchus mykiss). An experimental group of fish was exposed to Sencor 70 WG pesticide product (active substance 70% of metribuzin). The acute semistatical toxicity test lasting 96 h was performed on rainbow trout juveniles. The 96hLC50 value of Sencor 70 WG was 89.3 mg/l. An examination of the haematological and biochemical profile and histopathological tissue examinations were performed on one-to two-year-old rainbow trout after 96 h of exposure to Sencor WG 70 in a concentration of 89.3 mg/l. The experimental group showed significantly lower values (P < 0.01) of plasma total proteins, triacylglycerols, aspartate aminotransferase, ammonia, calcium, lactate, alkaline phosphatase, erythrocyte count, haematocrit and significantly higher (P < 0.01) values of erythrocyte haemoglobin compared to the control group. A significant decrease (P < 0.01) in both the relative and absolute lymphocyte count and a significant increase (P < 0.01) in both the relative and absolute count of neutrophile granulocytes were also recorded in the experimental group. The histopathological examination revealed mild proliferation of goblet cells of the respiratory epithelium of secondary gill lamellae and hyaline degeneration of epithelial cells of the renal tubules of the caudal kidney. This alteration of kidney resulted in hypoproteinaemia, followed by the formation of transudate in the body cavity. The metribuzin-based Sencor WG 70 pesticide product was classified among substances harmful to fish.

show abstract

“…This finding is consistent with the results of Bibi (2011), where sublethal concentration of γ-cyhalothrin caused significant increase in GR and POD activities in liver, brain and muscle tissues of Cyprinus carpio. However, in the liver of C. punctatus and bluegill sunfish (Lepomis macrochirus) initially, the GR activity was unchanged when exposed to different concentrations of atrazine, while enhanced activity was observed after 10 days (Elia et al, 2002;Nwani et al, 2010).…”

Section: Resultsmentioning

confidence: 99%

“…Enhancement of CAT activity was also reported in the mahseer Tor putitora and the common carp (Cyprinus carpio) in response to sublethal concentrations of pyrethroid (Atika, 2011;Bibi, 2011). Similarly, cichlid fishes, mullets Lepomis macrochirus, collected from polluted environments and Prochilobus lineatus in response to herbicide also showed higher CAT activity (Filho et al, 2001;Elia et al, 2002;Langiano and Martinez, 2008). However, in gilthead seabream Sparus aurata CAT activity was decreased in response to malathion pesticide (Rosety et al, 2005).…”

Section: Resultsmentioning

confidence: 99%

“…In fish, antioxidant enzymes activities depend on species, exposure time and dose of pollutant (Elia et al, 2002;Nwani et al, 2010), whereas feeding behavior and habitat also influence their activities (Ahmad et al, 2000). Thus, in literature wide variations in antioxidant enzymes activities in different tissues of various fish species have been observed.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Cypermethrin induced behavioral and biochemical changes in mahseer, <i>Tor putitora </i>

et al. 2014

View full text Add to dashboard Cite

-The purpose of this study was to evaluate behavioral responses and biochemical changes induced by the extensively used pesticide cypermethrin (CYP) in liver, gills, brain and muscle tissues of mahseer (Tor putitora) fry. Behavioral changes in fish after exposure to an acute concentration of CYP involved jumping, abrupt swimming, loss of balance and equilibrium, increased surface activity and air gulping. These changes were more prominent with the passage of time. After a longer period of exposure, the fish became sluggish and before dying occasionally became motionless and sometimes showed a vertical position. Internal hemorrhage was also obvious. CYP exposure resulted in a significant decrease in total protein content in different tissues while antioxidant enzymes, catalase (CAT), peroxidase (POD) and glutathione reductase (GR) showed a time-dependent increasing trend in their activities in liver, brain, gills and muscle tissues. Similarly, lipid peroxidation (LPO) level also increased with time in different tissues of CYP-exposed fish. The results of the present study revealed that CYP is toxic to the mahseer Tor putitora. Therefore, its indiscriminate use can contribute in decreasing the population of mahseer in natural water bodies.

show abstract

Biochemical Responses of Bluegill Sunfish ( Lepomis macrochirus , Rafinesque) to Atrazine Induced Oxidative Stress

Cited by 95 publications

References 0 publications

Melamine–cyanurate complexes and oxidative stress markers in trout kidney following melamine and cyanuric acid long-term co-exposure and withdrawal

Melamine–cyanurate complexes and oxidative stress markers in trout kidney following melamine and cyanuric acid long-term co-exposure and withdrawal

Effects of metribuzin on rainbow trout (Oncorhynchus mykiss)

Cypermethrin induced behavioral and biochemical changes in mahseer, <i>Tor putitora </i>

Contact Info

Product

Resources

About