Biochemical Markers of Bone Turnover during Pregnancy: A Longitudinal Study

Hellmeyer, L; Ziller, Volker; Anderer, G; Ossendorf, Andreas; Schmidt, S.; Hadji, P.

doi:10.1055/s-2006-951627

Cited by 30 publications

(24 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our study results are consistent with limited, previously reported data, showing low P1CP and P1NP concentration in the first trimester 28,30 with the tendency to rise above normal in the late pregnancy 30,31 . Since type I collagen constitutes 90% of bone proteins, it may be considered as very valuable and precise marker of bone formation.…”

Section: Discussionsupporting

confidence: 93%

Bone turnover markers in medicamentous and physiological hyperprolactinemia in female rats

Radojkovic

Pešić

Ristić³

2014

VOJNOSANIT PREGL

View full text Add to dashboard Cite

Physiological hyperprolactinemia does not have such harmful effect on bone metabolism as medicamentous hyperprolactinemia. Chronic medicamentous hyperprolactinemia produces lower serum levels of bone formation markers. Assessment of bone turnover markers in prolongated medicamentous hyperprolactinemia provides an opportunity for earlier diagnosis of bone metabolism disturbances and should be considered as mandatory.

show abstract

Section: Discussionsupporting

confidence: 93%

Bone turnover markers in medicamentous and physiological hyperprolactinemia in female rats

Radojkovic

Pešić

Ristić³

2014

VOJNOSANIT PREGL

View full text Add to dashboard Cite

show abstract

“…Pregnancy has been documented to be a state of marked enhancement of bone turnover [21], during which a significant loss in BMD could be clearly demonstrated by direct methods, including standard dual-energy X-ray absorptiometry (DXA) [11,22] and quantitative ultrasound [13-16]. This BMD loss is thought largely to be reversible in the long run [23,24].…”

Section: Discussionmentioning

confidence: 99%

Persistence of back pain symptoms after pregnancy and bone mineral density changes as measured by quantitative ultrasound - a two year longitudinal follow up study

Wong

2011

BMC Musculoskelet Disord

View full text Add to dashboard Cite

BackgroundPrevious research has shown a loss of bone mineral density (BMD) during pregnancy. This loss has been correlated to the occurrence of back pain symptoms during pregnancy. The objective of this study was to evaluate whether persistence of back pain symptoms 2 years after pregnancy could be associated with BMD changes as measured by quantitative USG of the os calcis.MethodsA cohort of patients who reported significant back pain symptoms during pregnancy were surveyed for persistent back pain symptoms 24 to 28 months after the index pregnancy. Os calcis BMD was measured by quantitative ultrasound and compared with the BMD values during pregnancy.ResultsA cohort of 60 women who had reported significant back pain symptoms in their index pregnancy completed a 24-28 months follow-up survey and BMD reassessment. Persistence of significant back pain symptoms was seen in 24 (40%) of this cohort. These women had higher BMD loss during pregnancy compared to those without further pain (0.047 Vs 0.030 g/cm2; p = 0.03). Those that remained pain free after pregnancy appeared to have completely recovered their BMD loss in pregnancy, while those with persistent pain had lower BMD values (ΔBMD - 0.007 Vs - 0.025 g/cm2; p = 0.023) compared to their early pregnancy values.ConclusionPersistence of back pain symptoms after pregnancy could be related to an inability to recover fully from BMD loss during the index pregnancy.

show abstract

“…Because BTMs have been shown to increase after a fracture and remain high for months afterward, 17,18 women with a history of fracture within the past 5 years were excluded from the study. Pregnancy also can affect BTM levels 19 ; therefore, women who were less than 1 year post-pregnancy were excluded from the study. Because concentrations of BTMs increase during puberty 20 and again during menopause, 21,22 premenopausal women aged 18 to 35 years were recruited.…”

Section: Samplingmentioning

confidence: 99%

Bone turnover marker profile in relation to the menstrual cycle of premenopausal healthy women

et al. 2008

View full text Add to dashboard Cite

show abstract

Biochemical Markers of Bone Turnover during Pregnancy: A Longitudinal Study

Cited by 30 publications

References 24 publications

Bone turnover markers in medicamentous and physiological hyperprolactinemia in female rats

Bone turnover markers in medicamentous and physiological hyperprolactinemia in female rats

Persistence of back pain symptoms after pregnancy and bone mineral density changes as measured by quantitative ultrasound - a two year longitudinal follow up study

Bone turnover marker profile in relation to the menstrual cycle of premenopausal healthy women

Contact Info

Product

Resources

About