“…New antineoplastic strategy based on differential induction of FROdependent mechanisms in normal and tumor cells has been proposed [1,11,13]. It should be noted that the use of most existing therapies in oncology is accompanied by the development of harmful effects of FRO on the cells of normal tissues and organs [1,5,6,[11][12][13]. These negative side effects are mostly caused by ROS and RNS that significantly limits the applied dosage of appropriate anticancer drugs [1,5,6,12,14].…”