“…In this regard, a remarkable development has recently been reported considering the discriminant features of both ZnO and Se NPs. 3 A novel hybridization approach was involved in fabricating spherical ZnO–Se core–shell NPs, as presented in Fig. 3.…”
Section: Potential Nanomaterials For Effective Treatmentmentioning
confidence: 99%
“…3. 3 Undoubtedly, the designed NPs depend on utilizing and combining the antibacterial advantages of both Se and ZnO by engineering novel potential alloy NPs. The average diameters of the fabricated ZnO–Se NPs were measured to be 90 nm, which stimulated potential killing effects against extracellular M. tuberculosis , including BCG and virulent H37Rv.…”
Section: Potential Nanomaterials For Effective Treatmentmentioning
confidence: 99%
“…Interestingly, intracellular inhibition growth could also be exhibited by promoting M1 polarization to enhance antiseptic nitric oxide production and developing apoptosis and autophagy of M. tuberculosis -infected macrophages by increasing the intracellular ROS, disrupting mitochondria membrane potential and inhibiting PI3K/Akt/mTOR signaling pathway. 3…”
Section: Potential Nanomaterials For Effective Treatmentmentioning
confidence: 99%
“…2 Globally, it is estimated that 10 million people have developed TB infection, and there are an estimated 1.8 million deaths annually due to primary disease, reinfection, or reactivation of the latent infection. 3 M. tuberculosis has a strong ability to adapt and survive in several host environments. It has a potential tendency to change its metabolic pathways and easily evade the host immune system through intracellular growth.…”
This review sheds light on the novel nanomaterials required for rapid and clear diagnosis of tuberculosis, and compiles and discusses their limitations and future prospects.
“…In this regard, a remarkable development has recently been reported considering the discriminant features of both ZnO and Se NPs. 3 A novel hybridization approach was involved in fabricating spherical ZnO–Se core–shell NPs, as presented in Fig. 3.…”
Section: Potential Nanomaterials For Effective Treatmentmentioning
confidence: 99%
“…3. 3 Undoubtedly, the designed NPs depend on utilizing and combining the antibacterial advantages of both Se and ZnO by engineering novel potential alloy NPs. The average diameters of the fabricated ZnO–Se NPs were measured to be 90 nm, which stimulated potential killing effects against extracellular M. tuberculosis , including BCG and virulent H37Rv.…”
Section: Potential Nanomaterials For Effective Treatmentmentioning
confidence: 99%
“…Interestingly, intracellular inhibition growth could also be exhibited by promoting M1 polarization to enhance antiseptic nitric oxide production and developing apoptosis and autophagy of M. tuberculosis -infected macrophages by increasing the intracellular ROS, disrupting mitochondria membrane potential and inhibiting PI3K/Akt/mTOR signaling pathway. 3…”
Section: Potential Nanomaterials For Effective Treatmentmentioning
confidence: 99%
“…2 Globally, it is estimated that 10 million people have developed TB infection, and there are an estimated 1.8 million deaths annually due to primary disease, reinfection, or reactivation of the latent infection. 3 M. tuberculosis has a strong ability to adapt and survive in several host environments. It has a potential tendency to change its metabolic pathways and easily evade the host immune system through intracellular growth.…”
This review sheds light on the novel nanomaterials required for rapid and clear diagnosis of tuberculosis, and compiles and discusses their limitations and future prospects.
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