Biochemical changes investigated by psoroptic mange infestation in buffaloes

Abstract

The present study was executed on fifty buffaloes (Bubalusbubalus), aged 1-3years, suffering from signs of pruritus and alopecia throughout the period from January to December 2015. Upon parasitological enquiry, they were proved to be infested by Psoroptes species. The changes in the serobiochemical parameters were compared in two groups, infested group and non infested healthy group, each of 30 buffaloes. The following parameters were assessed: serumtotal protein (TP), serum albumin (ALB), blood urea nitrogen (BUN), creatinine levels, serum enzymatic activities levels as glutamic-pyruvic transaminase (GPT), glutamic oxaloacetic transaminase (GOT), alkaline phosphastase (ALP), and lactate dehydrogenase (LDH), Oxidative and anti oxidative biomarkers as malondialdehyde (MDA), Glutathione S-transferase (GST), superoxide dismutase (SOD) and catalase (CAT), inflamatory parameters as C-reactive protein (CRP), pro inflammatory cytokines (IL6) and tumor necrosis factor (TNF). The results concluded a significant difference in the serum constituents (P<0.05) between the infested buffaloes and the non-infestedones.