Biobrane® Improves Wound Healing in Burned Children Without Increased Risk of Infection

Lal, Sophia; Barrow, Robert E.; Wolf, Steven E.; Chinkes, David L.; Hart, David K.; Heggers, John P.; Herndon, David N.

doi:10.1097/00024382-200014030-00013

Cited by 115 publications

(74 citation statements)

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“…Studies have shown that silver sulfadiazine enhances healing by stimulating epithelial migration and granulation tissue formation while another reported that it inhibits fibroblast proliferation and collagen maturation, while some studies demonstrated the effect that was comparable to control [49][50][51]. In our study, wound healing parameters in silver sulfadiazine-treated group and control group were comparable.…”

Section: Pathak Et Alsupporting

confidence: 65%

Effect of Ethanolic Extract of Cyanotis Cristata Leaves Applied Topically on Wound Healing in Wistar Rats

Pathak

Shenoy

Kiran

et al. 2017

Asian J Pharm Clin Res

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Objective: The objective of this study was to assess the effect of ethanolic extract of Cyanotis cristata leaves when applied topically on healing of wound in Wistar rats. Methods:C. cristata leaves were evaluated for its effect on healing of wound in three models, namely, incision, excision, and burn wound. Each model included five groups, each consisting of 6 rats. The five groups were as follows: Group I rats (control and ointment base), Group II rats (standard and silver sulfadiazine), and Group III, Group IV, Group V (treated with C. cristata extract ointment of 0.5%, 1%, and 2%, respectively). Variables evaluated included breaking strength in incision wound while it was contraction rate and epithelialization in excision and burn wound. One-way analysis of variance and Tukey's post hoc test was used to analyze data. Result:In incision wound, breaking strength in test group was significantly increased (p<0.001) as compared to control. In excision and burn wound of test group, time to epithelialization and contraction rate was significantly decreased (p<0.001). The granulation tissue from excision and burn wound showed increased collagen and less inflammatory cells in test groups in comparison to the control. Conclusion:The ethanolic extract of leaves of C. cristata, when applied topically, enhanced wound strength and accelerated healing of incision, excision, and burn wounds in rats.

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Section: Pathak Et Alsupporting

confidence: 65%

Effect of Ethanolic Extract of Cyanotis Cristata Leaves Applied Topically on Wound Healing in Wistar Rats

Pathak

Shenoy

Kiran

et al. 2017

Asian J Pharm Clin Res

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“…Again, Pham et al found that Biobrane did not significantly affect the number of dressing changes or need for pain medications when compared to silver sulfadiazine and TransCyte. 17,[27][28][29] Specific studies on the use of Biobrane in deep partial-thickness burns are limited.…”

Section: Innovative Deep Partial-thickness Burn Treatmentmentioning

confidence: 99%

New Innovations for Deep Partial-Thickness Burn Treatment with ACell MatriStem Matrix

Kim

Kaminsky

Summitt

et al. 2016

Advances in Wound Care

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“…Special treatment is necessary for the care of burned skin. Biobrane ® of Smith & Nephew consists of porcine collagen and allows faster healing time than conventional burn care [90]. It can also be used for the healing of transplanted skin.…”

Section: Commercial Productsmentioning

confidence: 99%

Hydrogels based on collagen and fibrin – frontiers and applications

Schneider-Barthold¹,

Baganz²,

Wilhelmi

et al. 2016

BioNanoMaterials

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Hydrogels are a versatile tool for a multitude of applications in biomedical research and clinical practice. Especially collagen and fibrin hydrogels are distinguished by their excellent biocompatibility, natural capacity for cell adhesion and low immunogenicity. In many ways, collagen and fibrin represent an ideal biomaterial, as they can serve as a scaffold for tissue regeneration and promote the migration of cells, as well as the ingrowth of tissues. On the other hand, pure collagen and fibrin materials are marked by poor mechanical properties and rapid degradation, which limits their use in practice. This paper will review methods of modification of natural collagen and fibrin materials to next-generation materials with enhanced stability. A special focus is placed on biomedical products from fibrin and collagen already on the market. In addition, recent research on the in vivo applications of collagen and fibrin-based materials will be showcased.

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Biobrane® Improves Wound Healing in Burned Children Without Increased Risk of Infection

Cited by 115 publications

References 0 publications

Effect of Ethanolic Extract of Cyanotis Cristata Leaves Applied Topically on Wound Healing in Wistar Rats

Effect of Ethanolic Extract of Cyanotis Cristata Leaves Applied Topically on Wound Healing in Wistar Rats

New Innovations for Deep Partial-Thickness Burn Treatment with ACell MatriStem Matrix

Hydrogels based on collagen and fibrin – frontiers and applications

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