Biobank – the key to personalized medicine

Abstract

Personalized medicine can be defined as a medical approach based on individualized information that allows planning and treatment considering the patient's clinical and genetic characteristics. Despite the great advance since the creation of the Human Genome Project aimed at identifying all the genes of human beings, the transcription of the gene was found to be not solely responsible for the result of our organism's responses. Therefore, the investigations of proteomics and metabolomics projects were also initiated, considering the transcription from deoxyribonucleic acid (DNA) to ribonucleic acid (RNA), its production of proteins and products of cellular metabolism. 1 Moreover, this data set needs to be associated with the patient's clinical information. The collection and storage of biological material enable a series of studies

Developing cancer biobanks in Romania: understanding the knowledge and recommendations in assessing a clinical dataset for biospecimens

“…On the other hand, the majority of participants declared they would accept the storage of their biological samples in a biobank to be used for future molecular analyses, if the standard oncology treatment proved inefficient ( Table II ). The trust of patients and healthcare professionals in developing biobanks that are built adhering to ethical and operational standards in Romania is important, as the development of artificial intelligence and databases allows advanced knowledge and connection of findings in different databases and, therefore brings the concept of personalized medicine closer to the clinical practice, with applications in early diagnosis and pharmacogenomics, to predict response to targeted therapy [ 13 – 15 ].…”