ObjectiveTo evaluate the level of knowledge of medical students about transplantation and
brain death. MethodsAn anonymous self-administered questionnaire answered by medical students from the
first through the sixth year that was based on information from the
Associação Brasileira de Transplante de Órgãos e Tecidos, the
Registro Brasileiro de Transplantes and the resolution that
defines the criteria for brain death. ResultsOf the 677 medical students asked, 310 (45.8%) agreed to answer the questionnaire.
In total, 22 (7.0%) subjects were excluded. Of the students who participated,
41.3% reported having already attended a class on organ transplantation and 33% on
brain death; 9.7% felt able to diagnose brain death (p<0.01); only 66.8%
indicated the kidney as the most transplanted solid organ in Brazil. ConclusionThe level of knowledge of medical students at this institution regarding brain
death and transplantation is limited, which may be the result of an inadequate
approach during medical school.
BACKGROUND: Lung transplantation (LTx) has been discussed as an option for treating irreversible lung fibrosis post-coronavirus disease 2019 (COVID-19), in selected cases. OBJECTIVES: To report on the initial experience and management of end-stage lung disease due to COVID-19 at a national center reference in Brazil. DESIGN AND SETTING: Cohort study conducted at a national reference center for lung transplantation. METHODS: Medical charts were reviewed regarding patients' demographics and pre-COVID-19 characteristics, post-LTx due to COVID-19. RESULTS: Between March 2020 and September 2021, there were 33 cases of LTx. During this period, we evaluated 11 cases of severe COVID-19-related acute respiratory distress syndrome (ARDS) that were potentially candidates for LTx. Among these, LTx was only indicated for three patients (9.1%). All of these patients were on venovenous extracorporeal membrane oxygenation (ECMO), and the procedure that they underwent was central venoarterial ECMO. All three patients were still alive after the first 30 postoperative days. However, patient #1 and patient #2 subsequently died due to fungal sepsis on the 47 th and 52 nd postoperative days, respectively. Patient #3 was discharged on the 30 th postoperative day. CONCLUSIONS: LTx is feasible among these complex patients. Survival over the first 30 days was 100%, and this favors surgical feasibility. Nonetheless, these were critically ill patients.
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