Bioavailability of antioxidant vitamins. Relation between the modality of intake and plasma markers of oxidative stress

Góralska, Joanna; Hartwich, J.; Siedlecka, D.; Gruca, Anna; Dolecki, Mirosław; Drozdz, Włodzimierz; Trzos, M.; Dembińska-Kieć, A.

doi:10.1007/s12263-007-0039-0

Cited by 2 publications

(1 citation statement)

References 3 publications

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“…22 A Cecil 3000 spectrophotometer with a temperature controlled cuvette holder (Cecil Instruments, Inc., Cambridge, England) was used. The total antioxidant status of the plasma (serum antioxidant vitamins A, E, and C, selenium [Se], ferric reducing/antioxidant power test [FRAP], thiol/albumin ratio) and malondialdehyde (MDA) 23 were measured using a novel automated colorimetric measurement method for the TAR developed by Erel.…”

Section: Methodsmentioning

confidence: 99%

Efficacy of Fentanyl and/or Lidocaine on Total Antioxidants and Total Oxidants During Craniotomy

Mızrak¹,

Erkutlu²,

Alptekin³

et al. 2011

Clinical Medicine & Research

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Objective: The aim of this study was to investigate the oxidative, hemodynamic, and analgesic effects of local lidocaine infiltration, or intravenous (IV) fentanyl injection, or a combination of lidocaine and IV fentanyl during head fixation in a 3-pin headrest in patients undergoing elective craniotomy.Design: Double-blind, randomized, placebo-controlled study. Setting: Gaziantep University Medical Faculty, Department of Anesthesiology and Reanimation.Methods: Eighty patients were randomly assigned to one of four groups. Five minutes before pin fixation, patients in group L received 1 mg/kg of lidocaine 2% for scalp infiltration (n=20), group F received 1 µg/kg of IV fentanyl (n=20), group FL received 1 mg/kg of lidocaine 2% and 1 µg/kg of fentanyl (n=20), and group P received a placebo (n=20). Following standard anesthesia, basal, pre-and post-fixational hemodynamic data were recorded. Blood samples were taken for evaluation of oxidant and antioxidant levels before and after pin fixation. Results:The total antioxidant levels after pin fixation were highest in group FL followed by group F, then group L and finally group P (ie, FL>F>L>P) (P<0.05). The mean arterial blood pressure (MAP) after pin fixation was higher than the MAP before pin fixation in groups L and P (P<0.05), but was lower in groups F and FL (P<0.05). Conclusion:The combination of fentanyl and lidocaine before pin fixation is useful in preventing severe hemodynamic response to pain stimuli, such as pin fixation, and in increasing total antioxidant levels in the post-fixational period during craniotomy in adults.

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Section: Methodsmentioning

confidence: 99%

Efficacy of Fentanyl and/or Lidocaine on Total Antioxidants and Total Oxidants During Craniotomy

Mızrak¹,

Erkutlu²,

Alptekin³

et al. 2011

Clinical Medicine & Research

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Relationship Between Oxidative Stress and Bone Mass in Obesity and Effects of Berry Supplementation on Bone Remodeling in Obese Male Mice: An Exploratory Study

Lee

Kim

Soung

et al. 2015

Journal of Medicinal Food

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Berry consumption can prevent bone loss. However, the effects of different berries with distinct anthocyanin composition have not been thoroughly examined. The present study compared the effects of blueberry, blackberry, and black currant on bone health using a mouse model of diet-induced obesity. To investigate the effect of different berry supplements against a high-fat (HF) diet in vivo, 40 HF diet-induced obese (DIO) C57BL mice were assigned into four groups and fed a HF diet (35% w/w) with or without berry supplementation for 12 weeks (n=10). We measured adipose tissue mass (epididymal and retroperitoneal), plasma antioxidant, bone-related biomarkers, femur bone mineral density (BMD), and bone mineral content (proximal and distal). Adipose masses were negatively correlated with proximal BMD, but positively associated with plasma superoxide dismutase (SOD) concentrations (P<.001). Berry supplementation did not change the plasma ferric reducing antioxidant power, SOD, and insulin-like growth factor-1. However, the black currant group exhibited greater plasma alkaline phosphatase compared with the control group (P<.05). BMD in the distal epiphysis was significantly different between the blueberry and blackberry group (P<.05). However, berry supplementation did not affect bone mass compared with control. The present study demonstrates a negative relationship between fat mass and bone mass. In addition, our findings suggest that the anthocyanin composition of berries will affect bone turnover, warranting further research to investigate the underlying mechanisms.

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Bioavailability of antioxidant vitamins. Relation between the modality of intake and plasma markers of oxidative stress

Cited by 2 publications

References 3 publications

Efficacy of Fentanyl and/or Lidocaine on Total Antioxidants and Total Oxidants During Craniotomy

Efficacy of Fentanyl and/or Lidocaine on Total Antioxidants and Total Oxidants During Craniotomy

Relationship Between Oxidative Stress and Bone Mass in Obesity and Effects of Berry Supplementation on Bone Remodeling in Obese Male Mice: An Exploratory Study

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