Bioactivity of noble metal nanoparticles decorated with biopolymers and their application in drug delivery

Rai, Mahendra; Ingle, Avinash P.; Gupta, Indarchand; Brandelli, Adriano

doi:10.1016/j.ijpharm.2015.10.059

Cited by 116 publications

(56 citation statements)

References 142 publications

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“…Biopolymers modified with nanoparticles (NPs) make possible their use for different applications like catalysis, optics, electronics, antimicrobial activity and drug delivery [16,21] (Figure 1). Drug delivery system provides productive attachment for therapeutics including drugs, proteins and nucleic acids with different roles like improvement of solubility, enhancement of in vivo stability, optimization of biodistribution and pharmacokinetics of drugs [16,22].…”

Section: Drug Delivery Applications Of Biopolymer Modified With Nanopmentioning

confidence: 99%

“…Drug delivery system provides productive attachment for therapeutics including drugs, proteins and nucleic acids with different roles like improvement of solubility, enhancement of in vivo stability, optimization of biodistribution and pharmacokinetics of drugs [16,22]. In recent years, interest has been stimulated by the capability of the NPs to bind a wide range of organic molecules, their low toxicity, and strong and tunable optical absorption.…”

Section: Drug Delivery Applications Of Biopolymer Modified With Nanopmentioning

confidence: 99%

“…Owing to their small size, nanoparticles can easily enter host cells and circulate through the body [16]. They are suitable for site specific delivery vehicles to carry large doses of chemotherapeutic agents or therapeutic genes to the target sites.…”

Section: Introductionmentioning

confidence: 99%

“…The modification of nanoparticles with various types of biopolymers can also contribute in their efficiency. Many biomolecules, including proteins, enzymes and oligopeptides [16,17], antibody and antigens and DNA/oligonucleotides/aptamers have been immobilized on the surface of nanoparticles to form nanoparticle-bimolecular conjugates [16,18].…”

Section: Introductionmentioning

confidence: 99%

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Effective Drug Delivery System of Biopolymers Based On Nanomaterials and Hydrogels - A Review

Gopi¹,

Amalraj²,

Thomas³

2016

Drug Des

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Design and synthesis of well-ordered drug delivery systems are very important for medicinal and pharmaceutical and health care. Innovations of materials through nanotechnology and hydrogels have synergistically energized the growth of drug delivery. Uniqueness in material chemistry permits the creation of environmentally approachable, biocompatible, biodegradable and targeted drug delivery system. Large numbers of biopolymers have been examined for the design of drug delivery systems. Structure, size, shape and multi-functionality of drug delivery system can be controlled by the nanotechnology combined with biopolymer. Hydrogels have also been investigated as smart delivery systems capable to release, at the appropriate time and site of action, entrapped drugs in response to specific physiological triggers. This review mainly focuses on drug delivery applications of nanoparticles modified biopolymers and effective drug delivery system of biopolymer network based on hydrogels.

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Section: Drug Delivery Applications Of Biopolymer Modified With Nanopmentioning

confidence: 99%

Section: Drug Delivery Applications Of Biopolymer Modified With Nanopmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Effective Drug Delivery System of Biopolymers Based On Nanomaterials and Hydrogels - A Review

Gopi¹,

Amalraj²,

Thomas³

2016

Drug Des

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“…Nanoparticles of noble metals have rich applications in the fields of material science, medicine, biology, physics and chemistry [1][2][3][4][5][6] . Silver nanoparticles (AgNPs) attractive more attention among the noble metals due to its exclusive properties like electrochemical, electrical conductivity, photo catalytic, chemical stability, magnetic, chemo catalytic and antimicrobial activities [7][8][9][10][11][12] .…”

Section: Introductionmentioning

confidence: 99%

Biosynthesis of Silver Nanoparticles Using Natural Plant Extract and Its Catalytic Reductive Degradation of Acid Violet 7

Yao¹,

Xing²,

Chen³

et al. 2017

dteees

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Abstract. In the present study, the silver nanoparticles (AgNPs) were biosynthesized using tea polyphenols in the silver nitrate solution. The tea polyphenols, which was extracted from the green tea leaves, acted as both reducing (from Ag + to Ag 0 ) and capping agent in the liquid phase. The synthesized AgNPs were characterized with UV-visible absorption spectrum, TEM, EDS spectrum and particles size distribution analysis. UV-visible absorption spectrum indicated a significant absorption peak at 425 nm related to the great synthesis of AgNPs in the aqueous solution. TEM images show the diameter of well dispersed AgNPs was around 28nm. The important parameters including pH value, silver nitrate concentration and temperature affected the synthetic reaction of AgNPs significantly. The AgNPs showed excellent catalytic activity in the degradation of Acid Violet 7 by NaBH 4 , and more than 97% Acid Violet 7 was degraded within 18 minutes.

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Nanostructurated Composites Based on Biodegradable Polymers and Silver Nanoparticles

Fufă

Fuf

Vlăsceanu

et al. 2017

Handbook of Composites From Renewable Materials

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Bioactivity of noble metal nanoparticles decorated with biopolymers and their application in drug delivery

Cited by 116 publications

References 142 publications

Effective Drug Delivery System of Biopolymers Based On Nanomaterials and Hydrogels - A Review

Effective Drug Delivery System of Biopolymers Based On Nanomaterials and Hydrogels - A Review

Biosynthesis of Silver Nanoparticles Using Natural Plant Extract and Its Catalytic Reductive Degradation of Acid Violet 7

Nanostructurated Composites Based on Biodegradable Polymers and Silver Nanoparticles

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