Bioactivity Evaluation of Peptide Fractions from Bighead Carp (Hypophthalmichthys nobilis) Using Alcalase and Hydrolytic Enzymes Extracted from Oncorhynchus mykiss and Their Potential to Develop the Edible Coats

Naghdi, Shahab; Lorenzo, José M.; Mirnejad, Reza; Ahmadvand, Mohsen; Moghaddam, Mehrdad Moosazadeh

doi:10.1007/s11947-022-02986-y

Cited by 8 publications

(1 citation statement)

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“…Most bioactive peptides derived from fish protein hydrolysates have been shown to have a broad range of deteriorative actions against diverse microbes, including bacteria, fungi, viruses, and protozoa [79,80]. They possess a wide range of antifungal and antimicrobial properties.…”

Section: Antimicrobial Peptidesmentioning

confidence: 99%

Extraction of Novel Bioactive Peptides from Fish Protein Hydrolysates by Enzymatic Reactions

et al. 2023

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Bioactive peptides derived from fish the byproduct protein hydrolysate have wide potential as functional food ingredients. The preparation of bioactive peptides is commonly achieved via enzymatic hydrolysis; this is the most preferred method because it has high specificity, fewer residual organic solvents in the product, and it is usually carried out in mild conditions. The use of various enzymes such as proteases is widely practiced in the industry, yet there are various limitations as it is of high cost and there is a limited availability of food-grade enzymes in the market. Moreover, high-throughput purification and the identification analysis of these peptides are currently being studied to further understand the functionality and characterization of the bioactive peptides. This review mainly focuses on the novel bioactive peptides derived from fish protein hydrolysates from various fish wastes and byproducts. The hydrolysis conditions, source of hydrolysate, and amino acid sequence of these novel peptides are presented, along with their corresponding methods of analysis in purification and identification. The use of various enzymes yields novel peptides with potent bioactivities, such as antiproliferative, antimicrobial, antihypertensive, antiglycemic, antitumor, and antioxidative biological functions. The increasing interest in proteomics in marine and aquatic waste utilization continues due to these products’ bioactivity and sustainability.

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Section: Antimicrobial Peptidesmentioning

confidence: 99%