Bioactive Natural Products from Traditionally used Mexican Plants

Pereda‐Miranda, Rogelio

doi:10.1007/978-1-4899-1778-2_5

Cited by 18 publications

(16 citation statements)

References 29 publications

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“…Fig. (3) is a reproduction of a drawing found in Hernandez's manuscripts of the bindweed acaquitl mecatl and which he accredited as being of "cold nature" [21], according to the European Galenic concept of convolvulaceous herbs to reduce excessive heat of the body in such forms as contemporarily defined as fevers, heart diseases, dysentery, epilepsy, hydrocephaly, meningitis, tumors, gastrointestinal infections and parasites [1]. At the beginning of the XX century, the jalap medicinal plant complex included "jalapa hembra" or "oficinal" (I. purga), "jalapa macho" (I. orizabensis) and "jalapa de Tampico" (I. simulans Hanbury) along with other species [5].…”

Section: Ethnomedicinal Rationalementioning

confidence: 99%

“…The cytotoxic potential was evaluated against four human cancer cultured cell lines, nasopharyngeal (KB), lung (A-549), breast (MCF-7) and colon (HT-29) carcinomas [1]. According to the National Cancer Institute guidelines (active leads, ED 50 < 20 µg/ml), the extracts prepared from the aerial parts of I. pes-caprae and I. batatas did not demonstrate any such activity.…”

Section: Screening For Cytotoxicitymentioning

confidence: 99%

“…Universidad Nacional Autónoma de México, Ciudad Universitaria, D.F. 04510, México; Tel: +52 55 5622 5288; Fax: + 52 55 5622 5329; E-mail: pereda@servidor.unam.mx markets, such as the so-called street-markets tianguis (Nahuatl tianquiztli, market), many on the same site for centuries before the Spaniards came to the New World, constitutes a rich source of ethnomedical information for effective selection of plants to be documented and evaluated by contemporary scientific approaches, since most of them have not been systematically studied [1].…”

Section: Introductionmentioning

confidence: 99%

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Biodynamic Constituents in the Mexican Morning Glories: Purgative Remedies Transcending Boundaries

Pereda‐Miranda¹,

Bah

2003

CTMC

Self Cite

125

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Jalap, a pre-Hispanic herbal remedy still considered a useful laxative, is an ingredient in some over-the-counter products sold by herbalists in contemporary Mexico. The purgative crude drugs are prepared from the roots of several morning glories species which all have been identified as members of the Ipomoea genus (Convolvulaceae). Their incorporation as therapeutical agents into Europe is an outstanding example of the assimilation of botanical drugs from the Americas as substitutes for traditional Old World remedies. Phytochemical investigations on the resin glycosides, main constituents of these drugs, were initiated during the second half of the XIX century; however, the structures of their active ingredients had remained poorly known, and still are for some members of these purgative root species. Modern analytical techniques with higher resolution capabilities (HPLC) for the isolation of the active principles of these crude drugs used in conjunction with powerful spectroscopic methods (high field NMR) have facilitated the investigation of these relevant, to the herbal product market, convolvulaceous species during the last decade. The advantages and limitations of theses techniques will be discussed. This review will also describe the ethnobotanical information associated with the Mexican morning glory species and how the traditional usages of these plants have played an important role in the selection of these materials for chemical studies. Little is as yet known about either the mechanism of purge action caused by the resin glycosides or the ecological significance of these same compounds for the producing plants. Over the five centuries of Mexican herbal medicine, one hundred years of phytochemistry has only partially elucidated the active ingredients of the jalap roots but has exemplified how to further contemporary drug discoveries through the investigation of those plants traditionally held to be economically and medicinally important in developing countries.

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Section: Ethnomedicinal Rationalementioning

confidence: 99%

Section: Screening For Cytotoxicitymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Biodynamic Constituents in the Mexican Morning Glories: Purgative Remedies Transcending Boundaries

Pereda‐Miranda¹,

Bah

2003

CTMC

Self Cite

125

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“…orizabensis As purgative (American and European pharmacopeas) (Pereda-Miranda, 1995), anthelmintic and to treat abdominal fever, dysentery, epilepsy, hydrocephaly, meningitis and tumors (Martinez, 1990).…”

Section: Nilmentioning

confidence: 99%

Review of the genus Ipomoea: traditional uses, chemistry and biological activities

Meira¹,

Silva²,

David³

et al. 2012

Rev. bras. farmacogn.

168

120

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Approximately 600-700 species of Ipomoea, Convolvulaceae, are found throughout tropical and subtropical regions of the world. Several of those species have been used as ornamental plants, food, medicines or in religious ritual. The present work reviews the traditional uses, chemistry and biological activities of Ipomoea species and illustrates the potential of the genus as a source of therapeutic agents. These species are used in different parts of the world for the treatment of several diseases, such as, diabetes, hypertension, dysentery, constipation, fatigue, arthritis, rheumatism, hydrocephaly, meningitis, kidney ailments and infl ammations. Some of these species showed antimicrobial, analgesic, spasmolitic, spasmogenic, hypoglycemic, hypotensive, anticoagulant, anti-infl ammatory, psychotomimetic and anticancer activities. Alkaloids, phenolics compounds and glycolipids are the most common biologically active constituents from these plant extracts.

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“…This genus, with way over 300 species, exhibits a major morphological diversity in the Brazilian Cerrado region (Harley, 1988). It has yielded a great number of important medicinal species that are frequently used as remedies in the treatment of gastrointestinal disturbances (Corrêa, 1931;Pereda-Miranda, 1995).…”

Section: Introductionmentioning

confidence: 99%

Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae)

Takayama

de-Faria

Almeida

et al. 2011

Journal of Ethnopharmacology

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Bioactive Natural Products from Traditionally used Mexican Plants

Cited by 18 publications

References 29 publications

Biodynamic Constituents in the Mexican Morning Glories: Purgative Remedies Transcending Boundaries

Biodynamic Constituents in the Mexican Morning Glories: Purgative Remedies Transcending Boundaries

Review of the genus Ipomoea: traditional uses, chemistry and biological activities

Gastroprotective and ulcer healing effects of essential oil from Hyptis spicigera Lam. (Lamiaceae)

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