Bioactive-glass in periodontal surgery and implant dentistry

Profeta, Andrea Corrado; Prucher, Gian Marco

doi:10.4012/dmj.2014-233

Cited by 31 publications

(25 citation statements)

References 64 publications

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“…PerioGlas ® , with particle size within 90–710 µm, can be pressed into bone defects, has been extensively used in periodontal surgical procedures to stimulate bone regeneration, especially in interproximal bone defects, and is beneficial due to its hemostatic effect on trabecular bone [71,156,157]. The formulation has also been evaluated radiographically in the treatment of apical osseous defects by endodontic surgery, which resulted in a higher success rate and earlier bone regeneration [158].…”

Section: Clinical Applications Of Bioactive Glasses In Dentistrymentioning

confidence: 99%

Bioactive Glass Applications in Dentistry

Skallevold

Rokaya

Khurshid

et al. 2019

IJMS

178

137

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At present, researchers in the field of biomaterials are focusing on the oral hard and soft tissue engineering with bioactive ingredients by activating body immune cells or different proteins of the body. By doing this natural ground substance, tissue component and long-lasting tissues grow. One of the current biomaterials is known as bioactive glass (BAG). The bioactive properties make BAG applicable to several clinical applications involving the regeneration of hard tissues in medicine and dentistry. In dentistry, its uses include dental restorative materials, mineralizing agents, as a coating material for dental implants, pulp capping, root canal treatment, and air-abrasion, and in medicine it has its applications from orthopedics to soft-tissue restoration. This review aims to provide an overview of promising and current uses of bioactive glasses in dentistry.

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Section: Clinical Applications Of Bioactive Glasses In Dentistrymentioning

confidence: 99%

Bioactive Glass Applications in Dentistry

Skallevold

Rokaya

Khurshid

et al. 2019

IJMS

178

137

View full text Add to dashboard Cite

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“…To date, numerous clinical studies evidenced that commercial 45S5 glass-based products demonstrate a better treatment approach than conventional methods [14][15][16][17][18][19][20][21][22], although results of those clinical trials suggest that evaluated materials induced a "repair" response rather than a true regenerative response [15,23]. Moreover, Profeta et al [15] concluded that, due to their granular nature, 45S5 glass-based products cannot serve reliably as spacemaking materials in sites where there was no support for a membrane while the soft tissue cover may cause its collapse during healing.…”

Section: Introductionmentioning

confidence: 99%

Injectable bioactive glass-based pastes for potential use in bone tissue repair

Tulyaganov

Akbarov²,

Ziyadullaeva³

et al. 2020

Biomedical Glasses

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In this study, injectable pastes based on a clinically-tested bioactive glass and glycerol (used as organic carrier) were produced and characterized for further application in regenerative medicine. The paste preparation route, apatite-forming ability in simulated body fluid (SBF) solution, viscoelastic behavior and structural features revealed by means of scanning electron microscopy (SEM), FTIR and Raman spectroscopy were presented and discussed, also on the basis of the major experimental data obtained in previous studies. A mechanism illustrating the chemical interaction between bioactive glass and glycerol was proposed to support the bioactivity mechanism of injectable pastes. Then, the results of In vivo tests, conducted through injecting moldable paste into osseous defects made in rabbit’s femur, were reported. Animal studies revealed good osteoconductivity and bone bonding that occurred initially at the interface between the glass and the host bone, and further supported the suitability of these bioactive glass pastes in bone regenerative medicine.

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“…Thus, understanding the science, technology and properties of B-G is a very important need for the oral healthcare community. This is a field of intense research, which is clearly manifested in the increasing number of publications with regard to its clinical applications [2, 12]. A number of authors listed the many benefits of this material in endodontic therapy [7, 14, 15] and associated microsurgery [27].…”

Section: Resultsmentioning

confidence: 99%

“…Since its introduction, the original B-G has been released as PerioGlas ® (now sold by NovaBone Products LLC, Alachua, FL, USA) demonstrating consistent results in a variety of bone regenerative treatments [3]. In periodontal surgical procedures, it has been used to stimulate bone regeneration, primarily in the treatment of interproximal bone defects [2]. This resulted in a 50-70% size reduction of bone cavities [28].…”

Section: Endodontic Microsurgerymentioning

confidence: 99%

Bioactive-glass in Endodontic Therapy and Associated Microsurgery

Profeta¹,

Prucher²

2017

Open Dent. J.

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Introduction:Bioactive-glass (B-G) has become a valuable adjunct to promote hard-tissue healing in many clinical situations and is of particular interest for endodontic care because of its biocompatibility, regenerative and antimicrobial properties as well as chemical composition that closely resembles the mineral make-up of human bone and dentine. Therapy:Initial studies suggested that bacteria-tight sealing within the entire root canal system can be achieved and successfully maintained after orthograde treatment. Promising results have also been obtained in conjunction with microsurgical techniques, with the aim of enhancing wound healing and positively influencing bone regeneration. Conclusion:Here, relevant literature was explored to present a comprehensive review of the rationale, development, and current applications of B-G in Endodontology illustrating them with case reports.

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Bioactive-glass in periodontal surgery and implant dentistry

Cited by 31 publications

References 64 publications

Bioactive Glass Applications in Dentistry

Bioactive Glass Applications in Dentistry

Injectable bioactive glass-based pastes for potential use in bone tissue repair

Bioactive-glass in Endodontic Therapy and Associated Microsurgery

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