Bioactive glass and biodegradable polymer composites

Niemelä, Tiiu; Kellomäki, Minna

doi:10.1533/9780857093318.2.227

Cited by 11 publications

(3 citation statements)

References 45 publications

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“…It is important to degrade the polymer that is injected. Biodegradable polymers are a class of synthetic or natural polymers that have the ability to decompose or degrade in the environment, primarily through natural biological processes, into nontoxic and environmentally friendly substances. − For nonbiodegradable polymers, the injected polymer can be broken up using a breaker so that it can flow back and be cleaned. The breaker effects on seawater fluid is explained in the following section.…”

Section: Gel Stabilizers Effects On Seawater Fluidmentioning

confidence: 99%

Seawater-Based Fracturing Fluid: A Review

Budiman,

Alajmei

2023

ACS Omega

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Hydraulic fracturing uses a large amount of fresh water for its operation; conventional wells can consume up to 200 000 gallons of water, while unconventional wells could consume up to 16 million gallons. However, the world's fresh water supply is rapidly depleting, making this a critical and growing problem. Freshwater shortages during large-scale hydraulic fracturing in regions that lack water, such as the Arabian Peninsula and offshore operations, need to be addressed. One of the ways to address this problem is to substitute fresh water with seawater, which is a sustainable, cheap, and technically sufficient fluid that can be utilized as a fracturing fluid. However, its high salinity caused by the multitude of ions in it could induce several problems, such as scaling and precipitation. This, in turn, could potentially affect the viscosity and rheology of the fluid. There are a variety of additives that can be used to lessen the effects of the various ions found in seawater. This review explains the mechanisms of different additives (e.g., polymers, surfactants, chelating agents, cross-linkers, scale inhibitors, gel stabilizers, and foams), how they interact with seawater, and the related implications in order to address the above challenges and develop a sustainable and compatible seawater-based fracturing fluid. This review also describes several previous technologies and works that have treated seawater in order to produce a fluid that is stable at higher temperatures, that has a considerably reduced scaling propensity, and that has utilized a stable polymer network to efficiently carry proppant downhole. In addition, some of these previous works included field testing to evaluate the performance of the seawater-based fracturing fluid.

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Section: Gel Stabilizers Effects On Seawater Fluidmentioning

confidence: 99%

Seawater-Based Fracturing Fluid: A Review

Budiman,

Alajmei

2023

ACS Omega

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“…are among the most extensively investigated BDPs for medicinal applications (Niemelä and Kellomäki 2011). They can easily be synthesised either by condensation or via ringopening polymerisation (Lipsa et al 2010).…”

Section: Poly (α-Hydroxy Acids)mentioning

confidence: 99%

Pharmaceutical, biomedical and ophthalmic applications of biodegradable polymers (BDPs): literature and patent review

Osi

Khoder

Al-Kinani

et al. 2022

Pharmaceutical Development and Technology

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In the last few decades, the interest in biodegradable materials for biomedical applications has increased significantly. Both natural and synthetic biodegradable polymers (BDPs) have been broadly explored for various biomedical applications.These include sutures and wound dressings, screws for bone fracture, scaffolds in tissue engineering, implants, and other carriers for targeted and sustained release drug delivery. Owing to their unique characteristics, including their surface charge variable copolymer block and composition and film-forming properties, BDPs have been widely used as favourable materials for ophthalmic drug delivery.Mucoadhesive BDPs have been used in ophthalmic formulations to prolong drug retention time and improve bioavailability, allowing ophthalmic controlled release systems to design. Furthermore, BDPs-based implants, microneedles, and injectable nano-and micro-particles enabled ocular posterior segment targeting and, most importantly, circumvented the need for removing the delivery systems after application. This review outlines the major advances of BDPs and highlights the latest progress of employing natural and synthetic BDPs for various biomedical applications, emphasising the treatment and management of ophthalmic conditions.

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“…Flexible optical waveguides based on biodegradable polymers do not need to be removed after implantation and can be naturally degraded in living organisms. These polymers contain the polymer chains that can be broken down through either hydrolytic degradation or enzymatic means, such as gelatin and agarose. Manocchi et al used gelatin as the core material and agarose as the cladding to produce a biocompatible and degradable planar optical waveguide .…”

Section: Soft and Stretchable Optical Waveguide And Novel Applicationsmentioning

confidence: 99%

Soft and Stretchable Optical Waveguide: Light Delivery and Manipulation at Complex Biointerfaces Creating Unique Windows for On-Body Sensing

Liu

2021

ACS Sens.

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Over the past few decades, optical waveguides have been increasingly used in wearable/implantable devices for onbody sensing. However, conventional optical waveguides are stiff, rigid, and brittle. A mismatch between conventional optical waveguides and complex biointerfaces makes wearable/implantable devices uncomfortable to wear and potentially unsafe. Soft and stretchable polymer optical waveguides not only inherit many advantages of conventional optical waveguides (e.g., immunity to electromagnetic interference and without electrical hazards) but also provide a new perspective for solving the mismatch between conventional optical waveguides and complex biointerfaces, which is essential for the development of light-based wearable/ implantable sensors. In this review, polymer optical waveguides' unique properties, including flexibility, biocompatibility and biodegradability, porosity, and stimulus responsiveness, and their applications in the wearable/implantable field in recent years are summarized. Then, we briefly discuss the current challenges of high optical loss, unstable signal transmission, low manufacturing efficiency, and difficulty in deployment during implantation of flexible polymer optical waveguides, and propose some possible solutions to these problems.

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Bioactive glass and biodegradable polymer composites

Cited by 11 publications

References 45 publications

Seawater-Based Fracturing Fluid: A Review

Seawater-Based Fracturing Fluid: A Review

Pharmaceutical, biomedical and ophthalmic applications of biodegradable polymers (BDPs): literature and patent review

Soft and Stretchable Optical Waveguide: Light Delivery and Manipulation at Complex Biointerfaces Creating Unique Windows for On-Body Sensing

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