Bioactive Constituents of Conyza albida

Pacciaroni, Adriana; Mongelli, E.; Espinar, L. Ariza; Romano, Alejandra; Ciccia, G.; Silva, Gloria L.

doi:10.1055/s-2000-9600

Cited by 23 publications

(19 citation statements)

References 15 publications

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“…Antibacterial and antifungal properties are attributed to the other compounds, such as E-caryophyllene and germacrene-D Veiga-Júnior and Pinto, 2002). On the other hand, spathulenol has antibacterial properties (Pacciaroni et al, 2000), which can explain the activity found.…”

Section: Resultsmentioning

confidence: 81%

Chemical composition, antimicrobial and antioxidant potential of the essential oil of Guarea kunthiana A. Juss

et al. 2017

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The essential oils are extracted from plant compounds and can present activities antimicrobial and antioxidant properties. The goals of the present study were: (a) to determine the chemical composition of the essential oil of Guarea kunthiana A. Juss using the method of gas chromatography coupled to mass spectrometry (GC-MS); (b) to evaluate the antimicrobial potential of this oil using the broth microdilution method against different microorganisms: five Gram-negative bacteria, four Gram-positive bacteria and a yeast and (c) to determine the antioxidant activity of the oil using the DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical assay. The GC-MS analyses allowed identifying 13 constituents, representing 96.52% of the essencial oil composition. The main compounds identified were α-zingiberene (34.48%), β-sesquiphellandrene (22.90%), and α-curcumene (16.17%). With respect to the antimicrobial activity, the essential oil was effective against all the microorganisms tested, except for the bacteria E. coli and K. pneumoniae, which were resistant to the action of the oil. From a general point of view, Gram-positive bacteria were more susceptible to the action of the essential oil than Gram-negative bacteria. The essential oil exhibited antioxidant potential.Keywords: Guarea kunthiana, essential oil, chemical composition, antimicrobial activity, antioxidant. Composição química, potencial antimicrobiano e antioxidante do óleo essencial de Guarea kunthiana A. Juss ResumoOs óleos essenciais são compostos extraídos de plantas e podem apresentar propriedades antimicrobianas e antioxidantes. O objetivo deste trabalho foi (a) determinar a composição química do óleo essencial de Guarea kunthiana A. Juss pelo método de cromatografia gasosa acoplada à espectrometria de massas (CG-EM); (b) avaliar o potencial antimicrobiano deste óleo pelo método de microdiluição em caldo frente a diferentes micro-organismos, sendo cinco bactérias Gram-negativas, quatro Gram-positivas uma levedura e (c) por fim, determinar a atividade antioxidante do óleo pelo método de captura do radical livre 2,2-difenil-1-picril hidrazil (DPPH). As análises de CG-EM resultaram na identificação de 13 constituintes, representando 96,52% da composição do óleo essencial. Os principais compostos identificados foram α-Zingibereno (34,48%), β-Sesquifelandreno (22,90%) e α-Curcumeno (16,17%). Em relação à atividade antimicrobiana, o óleo essencial foi efetivo frente a todos os micro-organismos testados exceto para as bactérias E. coli e K. pneumoniae, as quais se apresentaram resistentes à ação do óleo. Em geral, as bactérias Gram-positivas foram mais suscetíveis à ação do óleo essencial em relação às Gram-negativas. O óleo essencial apresentou potencial.Palavras-chave: Guarea kunthiana, óleo essencial, composição química, atividade antimicrobiana, antioxidante.

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Section: Resultsmentioning

confidence: 81%

Chemical composition, antimicrobial and antioxidant potential of the essential oil of Guarea kunthiana A. Juss

et al. 2017

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“…(Celastraceae) (Brenniesen and Geisshusler, 1985;Carlini, 2003), Conyza albida Spreng. (Asteraceae) (Pacciaroni et al, 2000;Stamatis et al, 2003), Lippia javanica (Burm. f.) Spreng.…”

Section: Resultsunclassified

In vitro antiplasmodial activity of medicinal plants native to or naturalised in South Africa

CLARKSON¹

2004

Journal of Ethnopharmacology

107

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The increasing prevalence and distribution of malaria has been attributed to a number of factors, one of them being the emergence and spread of drug resistant parasites. Efforts are now being directed towards the discovery and development of new chemically diverse antimalarial agents. The present study reports on the in vitro antiplasmodial activity of 134 plant taxa native to or naturalised in South Africa, representing 54 families, which were selected semi-quantitatively using weighted criteria. The plant extracts were tested for in vitro activity against a Plasmodium falciparum strain D10 using the parasite lactate dehydrogenase (pLDH) assay. Of the 134 species assayed, 49% showed promising antiplasmodial activity (IC 50 ≤ 10 g/ml), while 17% were found to be highly active (IC 50 ≤ 5 g/ml). Several plant species and genera were shown for the first time to possess in vitro antiplasmodial activity. These results support a rational rather than random approach to the selection of antiplasmodial screening candidates, and identify a number of promising taxa for further investigation as plant-based antimalarial agents.

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“…Los sesquiterpenos oxigenados, en particular el espatulenol, pueden haber desempeñado un papel muy importante en la actividad de este aceite esencial. Se ha verificado la actividad citotóxica del espatulenol (Pacciaroni et al, 2000). Otros aceites esenciales conteniendo espatulenol como compuesto mayoritario han mostrado actividad fitotóxica y antimicrobiana (Kobaisy et al, 2002;Ćavar et al, 2008).…”

Section: Discussionunclassified

Fitotoxicidad De Aceites Esenciales Y Extractos Acuosos De Plantas Mediterráneas Para El Control De Arvenses

Sancho¹,

Mercedes²

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Bioactive Constituents of Conyza albida

Abstract: Alkynes and spathulenol were isolated from Conyza albida (Asteraceae); some of the compounds were lethal against Artemia sp. and cytotoxic against KB cells.

Cited by 23 publications

References 15 publications

Chemical composition, antimicrobial and antioxidant potential of the essential oil of Guarea kunthiana A. Juss

Chemical composition, antimicrobial and antioxidant potential of the essential oil of Guarea kunthiana A. Juss

In vitro antiplasmodial activity of medicinal plants native to or naturalised in South Africa

Fitotoxicidad De Aceites Esenciales Y Extractos Acuosos De Plantas Mediterráneas Para El Control De Arvenses

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