Bio-nano hybrid materials based on bacteriorhodopsin: Potential applications and future strategies

Mahyad, Baharak; Janfaza, Sajjad; Hosseini, Elaheh

doi:10.1016/j.cis.2015.09.006

Cited by 36 publications

(26 citation statements)

References 82 publications

(138 reference statements)

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“…Recently, biomolecules such as bacteriorhodopsin and phycocyanin have been used in developing environmental friendly nanoscale devices . These photosensitive proteins are ultra sensitive to light and have a very high molar extinction coefficient.…”

Section: Introductionmentioning

confidence: 99%

Chlorophyll-a/ZnO Nanorod Based Hybrid Photoanodes for Enhanced Photoelectrochemical Splitting of Water

et al. 2017

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We report synthesis and use of Chlorophyll‐a/ZnO nanorod based hybrid photoanodes for photoelectrohemical (PEC) activity. Hybrid photoanodes consist of vertically oriented self ordered nanorod array of ZnO fabricated via electrodeposition followed by sensitization with chlorophyll‐a. Under AM 1.5 illumination (100 W/cm2), at 0.75 V bias, the hybrid photoanodes achieved a photocurrent density of 0.67 mA/cm2 which is ∼2.6 times increase over bare ZnO nanorods (0.26 mA/cm2). To the best of our knowledge, this is the first report on the use of Chlorophyll‐a/ZnO nanorod based hybrid electrodes in photoelectrochemical cells, with potential applications in switching and sensing.

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Section: Introductionmentioning

confidence: 99%

Chlorophyll-a/ZnO Nanorod Based Hybrid Photoanodes for Enhanced Photoelectrochemical Splitting of Water

et al. 2017

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“…NPs cannot be dispersed until they reach small enough dimensions to be functionalized for colloidal dispersibility. On the other hand, NP surfaces do not usually have uniformity and are not very convenient for chemical modifications (Mahyad et al, 2015). Thus, most conjugation (hybridization) reactions on NP surfaces are not completely homogeneous.…”

Section: Background: Nanobiocolloidalsmentioning

confidence: 99%

“…Multiple options based on size and surface area of NPs also contribute to the polydispersity for hybridization. The reaction stoichiometry usually does not depend on the NP biohybrid binding sites because hybrid reactions may not be well controlled (Stachowski et al, 2014;Mahyad et al, 2015). Thus, usually excess amounts of the biomolecules are employed in hybridization reactions, but these excess biomolecules should be isolated from the conjugates for the success of the intended biological application (Stachowski et al, 2014).…”

Section: Background: Nanobiocolloidalsmentioning

confidence: 99%

“…For example, aptamers within one QD can bind to the same target biomolecule (i.e. a protein with more than one homogeneous binding site) and might decrease the signal intensity (Mayoral et al, 1997;Lukianova-Hleb et al, 2012;Martinolich et al, 2012;Mkenzie et al, 2012;Monguzzi et al, 2014;Montano et al, 2014;Luo et al, 2015;Madden et al, 2015;Mahyad et al, 2015;Matea et al, 2015;Mishra et al, 2016).…”

Section: Semiconductor Quantum Dotsmentioning

confidence: 99%

“…For example, in dip-pen nanolithography, a high refractive index liquid is used between an imaging lens and other tools such as photoresists, e-beams, focused ion beams, and scanning probes. There are also two prominent methods for fabricating colloidal photonic crystals (André et al, 2016) and periodic plasmonic nanostructures (Malaczewska, 2014;Madden et al, 2015;Mahyad et al, 2015;Mansur et al, 2015;Del Mercato et al, 2016): electron-beam lithography and focused ion-beam milling. In addition to numerous similar nanooptical applications, the improvement of plasmonic structure and photonic crystals based on integrated optical circuits has been mostly hindered by sophisticated top-down nanofabrication techniques.…”

Section: Introductionmentioning

confidence: 99%

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Hybrid nanomaterial: biocolloidals

Gözübenli¹,

Yasun²,

Dilsiz³

2017

Turk J Biol

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Nanomaterials-based diagnostics have tremendous advantages over other conventional diagnostic systems in terms of sensitivity, specificity, and portability owing to the unique intrinsic properties of nanomaterials. Thus, there is a substantial need to develop and employ a broad spectrum of nanomaterials for biological and diagnostic applications. In this review, we focus on nanomaterials-assisted disease diagnosis utilizing different techniques such as photoluminescence, colorimetry, fluorescence, electrochemistry, microarray methods, surface plasmon resonance, and surface-enhanced Raman spectroscopy. In these techniques, different nanomaterials, including but not limited to gold and silver materials, metal oxides, and semiconductors, were employed according to their all-purpose chemical and physical properties. As the new properties of nanomaterials are discovered, their contributions to nanobiotechnology applications are vastly increased. In this review, the features of the selected nanobiomaterials, biological tag-modified nanomaterials, and their outstanding applications for the detection of specific biotargets have been summarized according to the latest studies. Nanomaterials contribute to the fields of photo/chemotherapy and biomedical imaging in particular, since all the biological events happen within this size range and beneficiary roles of nanoparticles (NPs) are countless in biomedical applications due to their unique physical and chemical properties. However, due to the necessity of specificity and selectivity, there is a clear ambition to study bioconjugation of NPs to increase the efficiency of the targeted biological applications. Thus, the combination of the specificity and the intrinsic properties of biohybrid NPs facilitate diagnostic and therapeutic applications.

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A Nano‐Biohybrid‐Based Bio‐Solar Cell to Regulate the Electrical Signal Transmission to Living Cells for Biomedical Application

Lim

Shin

et al. 2023

Advanced Materials

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Bio‐solar cells have been studied as sustainable and biocompatible energy sources with significant potential for biomedical applications. However, they are composed of light‐harvesting biomolecules with narrow absorption wavelengths and weak transient photocurrent generation. In this study, a nanobiohybrid‐based bio‐solar cell composed of bacteriorhodopsin, chlorophyllin, and Ni/TiO2 nanoparticles is developed for the first time to overcome the current limitations and verify the possibility of biomedical applications. Bacteriorhodopsin and chlorophyllin are introduced as light‐harvesting biomolecules to broaden the absorption wavelength. As a photocatalyst, Ni/TiO2 nanoparticles are introduced to generate a photocurrent and amplify the photocurrent generated by the biomolecules. The developed bio‐solar cell absorbed a broad range of visible wavelengths and generated an amplified stationary photocurrent density (152.6 nA/cm2) with a long lifetime (up to 1 month). Besides, the electrophysiological signals of muscle cells at neuromuscular junctions are precisely regulated by motor neurons excited by the photocurrent of the bio‐solar cell, indicating that the bio‐solar cell can control living cells by signal transmission through other types of living cells. The proposed nanobiohybrid‐based bio‐solar cell can be used as a sustainable and biocompatible energy source for the development of wearable and implantable biodevices and bioelectronic medicines for humans.This article is protected by copyright. All rights reserved

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Bio-nano hybrid materials based on bacteriorhodopsin: Potential applications and future strategies

Cited by 36 publications

References 82 publications

Chlorophyll-a/ZnO Nanorod Based Hybrid Photoanodes for Enhanced Photoelectrochemical Splitting of Water

Chlorophyll-a/ZnO Nanorod Based Hybrid Photoanodes for Enhanced Photoelectrochemical Splitting of Water

Hybrid nanomaterial: biocolloidals

A Nano‐Biohybrid‐Based Bio‐Solar Cell to Regulate the Electrical Signal Transmission to Living Cells for Biomedical Application

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