Bio-based materials with novel characteristics for tissue engineering applications – A review

Bedian, Luis; Villalba‐Rodríguez, Angel M.; Hernández-Vargas, Gustavo; Parra‐Saldívar, Roberto; Iqbal, Hafiz M.N.

doi:10.1016/j.ijbiomac.2017.02.048

Cited by 187 publications

(78 citation statements)

References 87 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Many research efforts have been made to engineer new types of high-performance materials-based constructs (Iqbal et al, 2014b;Iqbal et al, 2016a;Iqbal et al, 2016b;Iqbal et al, 2016c;Bedian et al, 2017). This area is moving towards the development of "greener" technologies and in turn, the principle of "going green" has directed this search towards eco-friendly materials.…”

Section: Potentialities and Opportunitiesmentioning

confidence: 99%

“…Owing to the emerging or re-emerging infectious diseases caused by various microorganisms, much attention is now being focused towards alternative and effective approaches to be adopted to control and limit such deadly infections (Tiwari et al, 2013;Dhama et al, 2014a;Dhama et al, 2014b;Prasad et al, 2018;Tiwari et al, 2018). In this context, novel materials with antimicrobial activities are attracting the considerable attention of both academia and industry, especially in the biomedical, and other health-related sectors of the modern world (Iqbal et al, 2014a;Iqbal et al, 2015a;Iqbal et al, 2015b;Bedian et al, 2017). Because of the growing consciousness and demands of legislative authorities, the manufacturer, to reduce bacterial population in healthcare facilities and possibly to cut pathogenic infections, development of novel anti-microbial active materials which are biocompatible and biodegradable are considered to be a potential solution to such a problematic issue.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Emerging Pathogens and Bioactive Materials: In Greening the 21st Century Biomedical Sciences

Iqbal¹,

Dhama²

2018

JEBAS

View full text Add to dashboard Cite

Emerging pathogens are a major threat to the biological safety of the world in the 21 st century. Owing to many reasons, the emergence and re-emergence of deadly pathogens have increased and posed a considerable challenge to human and animal health, alike. Various factors including ecological changes along with other specific risk factors related to the type and classification of the pathogen, route of transmission and host range are among the most commonly associated criterion for emerging and reemerging pathogenic environments. Owing to the lack of essential in-depth knowledge, challenges remain in this domain to tackle and combat emerging pathogens. Significant research efforts, exploitations of natural resources with potent bioactivities, and development of scientific innovations along with new degrees of integration are required to tackle this challenging threat. Aiming to resolve these issues, various methodological approaches including in -vitro, in-vivo, ex-vivo, etc. have been exploited, in the past several years. Research is underway around the globe to develop or engineer bioactive materials. Among them, biomaterials-based therapeutic constructs are of supreme interests in the current biomedical sector. The following measures, i.e. (i) principle sources of emerging pathogens, (ii) linking pathogen surveillance of wild and domestic animals, (iii) public health surveillance at the national and international level, and (iv) importantly the coverage of these surveillance issues, etc. should be taken with utmost care. This will ultimately make a significant and essential contribution to the detection and control of emerging and re-emerging pathogens.

show abstract

Section: Potentialities and Opportunitiesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Emerging Pathogens and Bioactive Materials: In Greening the 21st Century Biomedical Sciences

Iqbal¹,

Dhama²

2018

JEBAS

View full text Add to dashboard Cite

show abstract

“…In this context, two different technologies can be potentially combined to provide an efficient wound healing: matrices that will guide and support tissue regeneration (scaffolds) and concomitantly work as vehicles to drug delivery avoiding the ulcer infection. The technology of controlled release of drugs can potentially overpass many problems related to the traditional administration of active principles by regulating the rate and spatial localization of the released agent . Biodegradable polymers, such as microbial polyesters, have been investigated as raw materials to manufacture scaffolds applied to tissue regeneration and devices to drug delivery .…”

Section: Introductionmentioning

confidence: 99%

Swelling degree prediction of polyhydroxybutyrate/chitosan matrices loaded with “Arnica‐do‐Brasil”

Silva

Gobbi

et al. 2019

J of Applied Polymer Sci

View full text Add to dashboard Cite

Polyhydroxybutyrate and chitosan have been studied as materials for drug delivery systems (DDSs) due to their biodegradability and biocompatibility. The aim of this work was to produce amphiphilic polyhydroxybutyrate/chitosan matrices that form porous structures (scaffolds) after swelling in water and arnica extract. The matrices were analyzed by TGA, SEM, XDR, DSC, and FTIR. Thin plate spline interpolation method (TPSIM) was used to predict the swelling of the matrices generating three‐dimensional data fitted, showing the influence of time and concentration variables on both fluids absorption. Polyhydroxybutyrate/chitosan samples containing 60 wt % (weight percent) of chitosan formed a porous structure as they were submitted to arnica loading, and the obtained device was able to deliver arnica in physiological medium. Thus, the produced matrices have a strong potential to perform both as scaffolds and DDS © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47838.

show abstract

“…The main objective of skin tissue engineering is to replace or repair the damaged tissues and enable the cells to proliferate by providing protection and space . However, the elastic stretch ability is the major mechanical property of many tissue types therefore, the incorporation of special elastomeric biomaterials such as rubbery, soft, and flexible polymer substrate is necessary to mimic the native of extracellular matrix .…”

Section: Introductionmentioning

confidence: 99%

Nanofiber films of chloroacetated natural rubber/poly(vinyl alcohol) by electrospinning technique: Silica effects on biodegradation

Azarian

Boochathum

2018

J of Applied Polymer Sci

View full text Add to dashboard Cite

Green electrospinning technique was employed to prepare chloroacetated natural rubber (CNR)/poly(vinyl alcohol) (PVA) nanofiber films by varying the addition of PVA in the range 2.5–55 wt % followed by encapsulation of 2.5 wt % fumed silica (FS). In this study, the risk of using organic solvents was eliminated using CNR in latex. The encapsulated electrospun fiber mats showed a fairly homogenous composition with enhanced water absorption ability of 703.54% ± 33.95%. The FS improved the interfacial adhesion and contributed to enhancing the intermolecular interaction between the two polymers. The mean diameter of the nanofibers decreased from 64.0 ± 19.0 to 41.0 ± 13.0 nm and significant improvement in the hydrolytic and enzymatic degradation rate was observed implying that FS can facilitate the degradation rate. Furthermore, loading of PVA and encapsulation of FS resulted in an improved stiffness of CNR at room temperature and storage modulus increased to 2.48 and 2.12 MPa, respectively. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46432.

show abstract

Bio-based materials with novel characteristics for tissue engineering applications – A review

Cited by 187 publications

References 87 publications

Emerging Pathogens and Bioactive Materials: In Greening the 21st Century Biomedical Sciences

Emerging Pathogens and Bioactive Materials: In Greening the 21st Century Biomedical Sciences

Swelling degree prediction of polyhydroxybutyrate/chitosan matrices loaded with “Arnica‐do‐Brasil”

Nanofiber films of chloroacetated natural rubber/poly(vinyl alcohol) by electrospinning technique: Silica effects on biodegradation

Contact Info

Product

Resources

About