Bio analytical validation for nadolol and bendroflumethiazide material

K, Naveen V M; Veeraswami, B.; Rao, G. Srinivasa

doi:10.1016/j.matpr.2020.10.386

Cited by 2 publications

(2 citation statements)

References 4 publications

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“…For many neurological illnesses, such as the prevention of migraine attacks, attention/deficit/hyperactivity disorder (ADHD), it is effective, and it has been explored as a treatment for tremor and Parkinson's disease [20] Still, neither is well established [21]. Some bioanalytical studies are also supports the proposed approaches [22][23][24]. Its structure is shown in Fig.…”

Section: Original Research Articlementioning

confidence: 99%

Bio-Analytical Stability Studies of Nadolol Material

Veeraswami

2021

JPRI

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The best practices of Bio-analytical stability studies on drug samples are very crucial and essential for the drugs development process as it specify the acceptancy, purity, efficacy, prediction of strength and quality of the drugs. The main objective of this stability studies on Nadolol the proposed approach of chromatographic separation was administered in isocratic way by using asymmetric C18 column of 40:60 percent of acetonitrile and 0.1% OPA at a flow rate of 1 ml/min is a quantitative measure for drug analysis in biological matrix for more reliable, selective, reproducible and sensitive. This stability study constituents several methods like Bench-Top, Auto-sampler, Freeze-Thaw, Dry-extract, Wet-extract, Short-term, long-Term stability studies at various intervals gave the complete stability information about these drugs. The results of these stability studies are accepted based on ICH guidelines represents this drug has a good stability under the present experimental conditions.

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Section: Original Research Articlementioning

confidence: 99%

Bio-Analytical Stability Studies of Nadolol Material

Veeraswami

2021

JPRI

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“…Its structure shown in Fig. 1 and it was patented in 1958 & it was used for medical usage [4][5][6][7] in 1960. The mechanism of action of this drug as diuretic [8] nature it inhibit reabsorption of active chlorine increases the excretion of NaCl and H2O.…”

Section: Introductionmentioning

confidence: 99%

Bio-analytical Approach for Stability Studies of Bendroflumethiazide Materials

Veeraswami

2021

JPRI

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In this paper a comprehensive study of stability related, and evidence based best practices of Bio-analytical stability on Bendroflumethiazide drug samples are studied. The proposed approach is very significant and essential for the drugs development process address the specify the acceptancy, purity, efficacy, prediction of strength and quality of the drugs. The stability study constituents several methods like Bench-Top, Auto-sampler, Freeze-Thaw, Dry-extract, Wet-extract, Short-term, long-Term stability studies at relative intervals results the complete stability information about the drug under the proposed and validated method. There ported out comes of this methos shows this drug have good stability according to ICH guidelines.

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Bio analytical validation for nadolol and bendroflumethiazide material

Cited by 2 publications

References 4 publications

Bio-Analytical Stability Studies of Nadolol Material

Bio-Analytical Stability Studies of Nadolol Material

Bio-analytical Approach for Stability Studies of Bendroflumethiazide Materials

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