Binding Promises

Slawson, W. David

doi:10.1515/9781400821969

Cited by 27 publications

(3 citation statements)

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“…Both programs seek to make business agents the "eyes, ears and foot soldiers" of city inspectors. 79 Agents interview employees about hours worked, wages, job classification, official duties, and problems receiving pay, and they fill out wage-complaint forms with workers on the spot when violations are found. They do not determine violations or assess penalties but provide the raw data that city inspectors use to put together cases.…”

Section: Three Case Studies Los Angeles Unified School District and Board Of Public Work Deputization Programsmentioning

confidence: 99%

Strengthening Labor Standards Enforcement through Partnerships with Workers’ Organizations

Fine

Gordon

2010

Politics & Society

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Structures of employment in low-wage industries, a diminished wage and hour inspectorate, and an unworkable immigration regime have combined to create an environment where violations of basic workplace laws are everyday occurrences. This article identifies four “logics” of detection and enforcement, arguing that there is a mismatch between the enforcement strategies of most federal and state labor inspectorates and the industries in which noncompliance continues to be a problem. In response, the authors propose augmenting labor inspectorates by giving public interest groups like unions and worker centers a formal, ongoing role in enforcement in low-wage sectors. In three case studies, the authors present evidence of an emergent system—one that harkens back to a logic proposed by the drafters of the Fair Labor Standards Act (FLSA) but never implemented—of empowering those closest to the action to work in partnership with government.

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Section: Three Case Studies Los Angeles Unified School District and Board Of Public Work Deputization Programsmentioning

confidence: 99%

Strengthening Labor Standards Enforcement through Partnerships with Workers’ Organizations

Fine

Gordon

2010

Politics & Society

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“…88,89 Abnormal O-GlcNAcylation is correlated with various diseases including neurodegenerative disorders, diabetes, and cancers. 90 The developments of modern MS-based proteomics and novel enrichment methods have greatly facilitated our understanding of protein O-GlcNAcylation.…”

Section: O-gicnacmentioning

confidence: 99%

Recent Advances in Glycoproteomic Analysis by Mass Spectrometry

2019

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Glycosylation is one of the most common protein modifications and is essential for cells. This modification is exceptionally complex because glycans are highly diverse and can be covalently bound to several amino acid residues in proteins through various configurations. There are two major types of protein glycosylation, i.e., N-linked glycosylation in which glycans are attached to the side chain of asparagine and O-linked glycosylation referring to glycans being bound to the side chains of serine and threonine. 1,2 Glycosylation plays vital roles in cells, including determination of protein folding, trafficking and stability, and regulation of nearly every extracellular activity such as cell-cell communication and cellmatrix interactions. 3,4 Aberrant protein glycosylation is directly related to multiple diseases, including cancer, neurodegenerative disorders, pulmonary diseases, blood disorders, and genetic diseases. 5,6 Due to the importance and complexity of protein glycosylation in biological systems, there is a longstanding interest to develop innovative methods to study glycoproteins and apply them for biomedical research. Investigation of protein glycosylation has become more popular with the development of modern instrumentation and computational methods. According to a PubMed search using the keyword "glycosylation", 16 publications were listed during 1960-1970 while over 20 000 studies were reported in the past 10 years. With the growing interests in protein glycosylation, this trend is expected to continue in the next decades.Mass spectrometry (MS)-based proteomics provides an excellent opportunity to globally analyze proteins and their modifications. [7][8][9][10][11][12][13][14][15][16][17][18][19] Nonetheless, it is still extremely challenging to comprehensively analyze protein glycosylation. 20 Unlike many other modifications with a fixed structure for the modified group, such as phosphorylation, the diversity of glycans makes it more challenging to employ the commonly used database searching methods such as SEQUEST and Mascot to identify glycopeptides in bottom-up proteomics. Lowabundance glycoproteins in complex biological samples are also hindered for detection by many high-abundance nonglycoproteins. Furthermore, glycans can interfere with the fragmentation of the peptide backbone. 20,21 Innovative and effective methods are critical to overcome these hurdles and to allow for comprehensive analysis of glycoproteins using MS.

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“…), developed a different philosophy of reality. Plato's view, in contrast with Socrates, was that humans were fallible, limited in our abilities, our senses were inadequate to interpret reality, which he described as Form, or the perfect idea, existing only in the spiritual world [53]. These ontological positions are seen in safety science today as Interpretivism and Positivism respectively.…”

Section: The Ontological Dividementioning

confidence: 99%

Knowing versus understanding: adjusting the contextual lens in safety science

McCall

2020

MATEC Web Conf.

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Preparing for the unknown safety threat requires new ways of studying safety in today’s highly complex and dynamic environment. Qualitative inquiry offers advantages to expand the contextual lens in safety science by broadening understanding of the environment and conditions people negotiate in normal day-to-day operations. Through the narrative accounts of those with first-hand experience qualitative researchers seek to narrow the gap between work-as-done and work-as-imagined. It is through their individual experience, when analyzed collectively, that a greater context emerges. To aid in determining which research method is best for investigating safety phenomenon, this paper offers an overview of the philosophical underpinnings of qualitative research as well as recent examples from aviation, maritime, and mining.

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Binding Promises

Cited by 27 publications

References 0 publications

Strengthening Labor Standards Enforcement through Partnerships with Workers’ Organizations

Strengthening Labor Standards Enforcement through Partnerships with Workers’ Organizations

Recent Advances in Glycoproteomic Analysis by Mass Spectrometry

Knowing versus understanding: adjusting the contextual lens in safety science

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