A. Mikel my warran ty orrepre ,entatio n, exprea sed or implied , with respec t to the accuracy, complo teness . or usefuln m ot the inform 'lon contain ed in Ults report. or that the use of any informa tion, appara tui, metbod , or proces e disclos ed in thia report .sy not In[rtng .private ly owned rights, or B. Assum es any llabillti es ilth reipiet to the uie of. or for damag es restill]n g from the m of any infer mauon, apparat wi. method , or proceas disc told in thim report.Am uied in the above. "person actiag on behalf of the Comou s,lon" Include s any employee or contrac tor of the Comm isslon, or employ ee or Buch contrac tur, to tbe extent that such employ ee or contrac tor of the Comm ission, or employe e of such co*act or prepar es, dissem inatea, or provide e access to, any informa llon pur,Ian t to his employ ment or eontrao t wlth the Comm ission, or his employ mant witb such contrac tor.Presented at the New York Academy of Sciences Conference on Leukopoiesis in Health and Disease. May 9, 1963.--*
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DISCLAIMERPortions of this document may be illegible in electronic image products. Images are produced from the best available original document.-1-The purpose of this paper is to present data which gives some insight into. the rate of cell proliferation within the lymphatic nodules of the rat's spleen.In this study the technique of labeling DNA wish the specific precursor tritiawas used.ted thymidlnel The observations were made on the Malptghtaft. zorpuscles of the spleen utilizing autoradiographic methods.The lymphatic nature of the Malphighian corpuscles was first recognized However, as will be discussed later, the apparent increase in labeling indisx descrlbed may have a r.ational basis. During the first 1•1/2 days while the grain count was diminishing, the index of labeling remaf.ned above 30 psr cent. This is of lmpol'tance. in latel' interpretation.grain countThe 'labeling indices are highly dependant upon the arbitrary threshold /for positivity. Accordingly, in Pig. 3 the labeling index for different grain counts -is plotted. During the first 24 hours, frequent sacrifices were made. Accordand ingly, in this interval data is po...