Binaural processing after corrected congenital unilateral conductive hearing loss

Wilmington, Debra; Gray, Lincoln; Jahrsdoerfer, Robert A.

doi:10.1016/0378-5955(94)90179-1

Cited by 110 publications

(115 citation statements)

References 22 publications

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“…Nor do our findings of decreased activity in auditory cortex contralateral to CHL suggest an irretrievable loss of cortical function. For example, human performance on a number of auditory tasks improve after repair of congenital unilateral CHL, however, deficits in sound localization persist as do deficits in complex speech intelligibility (e.g., Wilmington et al, 1994). Given that amplitude and frequency modulation are substantial components of speech, the effect of CHL on cognitive and perceptual functions may be related to how the auditory system parcels the analysis of rapidly changing temporal stimuli, that is, a difference between AI and AAF (e.g., Linden et al, 2003).…”

Section: Perceptual Consequences Of Unilateral Chlmentioning

confidence: 99%

Consequences of unilateral hearing loss: Cortical adjustment to unilateral deprivation

Hutson¹,

Durham²,

Imig³

et al. 2008

Hearing Research

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The effect of unilateral hearing loss on 2-deoxyglucose (2-DG) uptake in the central auditory system was studied in post-natal day 21 gerbils. Three weeks following a unilateral conductive hearing loss (CHL) or cochlear ablation (CA), animals were injected with 2-DG and exposed to an alternating auditory stimulus (1 and 2 kHz tones). Uptake of 2-DG was measured in the inferior colliculus (IC), medial geniculate (MG), and auditory cortex (fields AI and AAF) of both sides of the brain in experimental animals and in anesthesia-only sham animals (SH). Significant differences in uptake, compared to SH, were found in the IC contralateral to the manipulated ear (CHL or CA) and in AAF contralateral to the CHL ear. We hypothesize that these findings may result from loss of functional inhibition in the IC contralateral to CA, but not CHL. Altered states of inhibition at the IC may affect activity in pathways ascending to auditory cortex, and ultimately activity in auditory cortex itself. Altered levels of activity in auditory cortex may explain some auditory processing deficits experienced by individuals with CHL.

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Section: Perceptual Consequences Of Unilateral Chlmentioning

confidence: 99%

Consequences of unilateral hearing loss: Cortical adjustment to unilateral deprivation

Hutson¹,

Durham²,

Imig³

et al. 2008

Hearing Research

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“…Sensitivity to ITDs decreases with ageing (Herman et al 1977;Abel et al 2000;Babkoff et al 2002), and is typically impaired in hearing loss, albeit variability across individuals and aetiologies (see Moore et al 1991, for review), with reduced sensitivity most apparent when trying to localise sources in background noise (Lorenzi et al 1999). ITD processing may also remain impaired following surgery to correct conductive hearing loss (Wilmington et al 1994), and sensitivity to ITDs is typically poor in users of hearing technologies such as bilateral cochlear implants (CIs). In terms of restoring binaural function in therapeutic interventions, there is considerable benefit to be gained from developing objective measures to assess binaural processing.…”

Section: Advantages Of Binaural Listeningmentioning

confidence: 99%

Objective Measures of Neural Processing of Interaural Time Differences

McAlpine¹,

Haywood²,

Undurraga³

et al. 2016

Advances in Experimental Medicine and Biology

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We assessed neural sensitivity to interaural time differences (ITDs) conveyed in the temporal fine structure (TFS) of low-frequency sounds and ITDs conveyed in the temporal envelope of amplitude-modulated (AM'ed) high-frequency sounds. Using electroencephalography (EEG), we recorded brain activity to sounds in which the interaural phase difference (IPD) of the TFS (or the modulated temporal envelope) was repeatedly switched between leading in one ear or the other. When the amplitude of the tones is modulated equally in the two ears at 41 Hz, the interaural phase modulation (IPM) evokes an IPM following-response (IPM-FR) in the EEG signal. For low-frequency signals, IPM-FRs were reliably obtained, and largest for an IPM rate of 6.8 Hz and when IPD switches (around 0°) were in the range 45-90°. IPDs conveyed in envelope of high-frequency tones also generated IPM-FRs; response maxima occurred for IPDs switched between 0° and 180° IPD. This is consistent with the interpretation that distinct binaural mechanisms generate the IPM-FR at low and high frequencies, and with the reported physiological responses of medial superior olive (MSO) and lateral superior olive (LSO) neurons in other mammals. Low-frequency binaural neurons in the MSO are considered maximally activated by IPDs in the range 45-90°, consistent with their reception of excitatory inputs from both ears. High-frequency neurons in the LSO receive excitatory and inhibitory input from the two ears receptively-as such maximum activity occurs when the sounds at the two ears are presented out of phase.

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“…For example, children with corrected or resolved chronic middle ear disease demonstrate atypical binaural processing as evidenced by smaller masking-level differences than normal-hearing (NH) controls (Hall and Grose 1994b;Hall et al 1995). Similarly, patients with successfully repaired unilateral congenital aural atresia show atypical performance on some binaural processing measures (Wilmington et al 1994). Children with prelingual sensorineural hearing loss appear to be more susceptible to informational masking than children with NH (Kidd et al 2002).…”

Section: Introductionmentioning

confidence: 99%

“…There is ample evidence in the literature that early atypical auditory stimulation (including hearing loss) has an impact on development of basic psychoacoustic abilities (e.g., Hall and Grose 1994b;Hall et al 1995;Wilmington et al 1994;Kidd et al 2002;Rance et al 2004;Halliday andBishop 2005, 2006). For example, children with corrected or resolved chronic middle ear disease demonstrate atypical binaural processing as evidenced by smaller masking-level differences than normal-hearing (NH) controls (Hall and Grose 1994b;Hall et al 1995).…”

Section: Introductionmentioning

confidence: 99%

Acoustic Temporal Modulation Detection in Normal-Hearing and Cochlear Implanted Listeners: Effects of Hearing Mechanism and Development

Park

Won

Horn

et al. 2015

JARO

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Temporal modulation detection ability matures over many years after birth and may be particularly sensitive to experience during this period. Profound hearing loss during early childhood might result in greater perceptual deficits than a similar loss beginning in adulthood. We tested this idea by measuring performance in temporal modulation detection in profoundly deaf children and adults fitted with cochlear implants (CIs). At least two independent variables could constrain temporal modulation detection performance in children with CIs: altered encoding of modulation information due to the CIauditory nerve interface, and atypical development of central processing of sound information provided by CIs. The effect of altered encoding was investigated by testing subjects with one of two different hearing mechanisms (normal hearing vs. CI) and the effect of atypical development was studied by testing two different age groups. All subjects were tested for their ability to detect acoustic temporal modulations of sound amplitude. A comparison of the slope, or cutoff frequency, of the temporal modulation transfer functions (TMTFs) among the four subject groups revealed that temporal resolution was mainly constrained by hearing mechanism: normal-hearing listeners could detect smaller amplitude modulations at high modulation frequencies than CI users. In contrast, a comparison of the height of the TMTFs revealed a significant interaction between hearing mechanism and age group on overall sensitivity to temporal modulation: sensitivity was significantly poorer in children with CIs, relative to the other three groups. Results suggest that there is an agespecific vulnerability of intensity discrimination or non-sensory factors, which subsequently affects sensitivity to temporal modulation in prelingually deaf children who use CIs.

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Binaural processing after corrected congenital unilateral conductive hearing loss

Cited by 110 publications

References 22 publications

Consequences of unilateral hearing loss: Cortical adjustment to unilateral deprivation

Consequences of unilateral hearing loss: Cortical adjustment to unilateral deprivation

Objective Measures of Neural Processing of Interaural Time Differences

Acoustic Temporal Modulation Detection in Normal-Hearing and Cochlear Implanted Listeners: Effects of Hearing Mechanism and Development

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