Bimodal Treatment of a Huge Hypervascular Neurofibroma on the Groin

Lü

2021

Science Progress

Neurofibroma is a rare nerve sheath tumor of neuroectodermal origin, especially the huge and isolated neurofibroma located in the inguinal region. To our knowledge, no such case has previously been reported. We report a case of 34-year-old male patient with a 4-year history of progressive enlargement of the medial root mass in his left thigh with sitting and standing disorders along with pain. The tumor was completely removed by operation, and pathological diagnosis showed neurofibroma. There was no obvious neurologic defect after surgery, and no recurrence tendency was found in the follow-up of 2 years. For a large solitary mass with slow growth and no malignant clinical manifestations for a long time, clinicians cannot rule out the hypothetical diagnosis of neurofibroma, even though its growth site is very rare, such as this case of a huge tumor located in the groin. For neurogenic tumors, early operation should be performed, and the prognosis of patients after tumor resection is excellent.

Section: Discussionmentioning

confidence: 99%

A solitary giant neurofibroma of inguinal region: A case report

Lü

2021

Science Progress

“…Among them, the solitary neuro broma is usually a small polypoid mass with its maximum size of less than 2 cm(4, 11). Most neuro bromas appear as single lesions in dermis or subcutaneous, but there are still 10% cases related to NF-1, which is an autosomal dominant genetic disease, formerly known as Von Recklinghausen disease, with clinical features of cafe-au-lait pigmentation, benign skin and subcutaneous tumor known as neuro broma, characteristic osteopathy, iris focal malformation (12,13).…”

Section: Discussionmentioning

confidence: 99%

A Solitary Giant Neurofibroma of Inguinal Region—A Case Report

Lü²

2020

Preprint

Abstract Background:Neurofibroma is a rare nerve sheath tumorofneuroectodermal origin, especially the huge and isolated neurofibroma located in the inguinal region. To our knowledge, no such case has previously been reported.Case presentation:We report a case of 34-year-old male patient with a 4-year history of progressive enlargement of the medial root mass in his left thigh with sitting and standing disorders along with pain. The tumor was completely removed by operation, and pathological diagnosisshowed neurofibroma. There was no obvious neurologic defect after surgery, and no recurrence tendency was found in the follow-up of 2years.Conclusions:For a large solitary mass with slow growth and no malignant clinical manifestations for a long time, clinicians can not rule out the hypothetical diagnosis of neurofibroma, even though its growth site is very rare, such as this case of a huge tumor located in the groin. For neurogenic tumors, early operation should be performed, and the prognosis of patients after tumor resection isexcellent.

“…Among them, the solitary neuro broma is usually a small polypoid mass with its maximum size of less than 2 cm (4,11). Most neuro bromas appear as single lesions in dermis or subcutaneous, but there are still 10% cases related to NF-1, which is an autosomal dominant genetic disease, formerly known as Von Recklinghausen disease, with clinical features of cafe-au-lait pigmentation, benign skin and subcutaneous tumor known as neuro broma, characteristic osteopathy, iris focal malformation (12,13).…”

Section: Discussionmentioning

confidence: 99%

A Solitary Giant Neurofibroma of Inguinal Region——A Case Report

Lü

2020

Preprint

BackgroundNeurofibroma is a rare nerve sheath tumor of neuroectodermal origin, especially the huge and isolated neurofibroma located in the inguinal region. To our knowledge, no such case has previously been reported.Case presentationWe report a case of 34-year-old male patient with a 4-year history of progressive enlargement of the medial root mass in his left thigh with sitting and standing disorders along with pain. The tumor was completely removed by operation, and pathological diagnosis showed neurofibroma. There was no obvious neurologic defect after surgery, and no recurrence tendency was found in the follow-up of 2 years.ConclusionsFor a large solitary mass with slow growth and no malignant clinical manifestations for a long time, clinicians can not rule out the hypothetical diagnosis of neurofibroma, even though its growth site is very rare, such as this case of a huge tumor located in the groin. For neurogenic tumors, early operation should be performed, and the prognosis of patients after tumor resection is excellent.